Доступ предоставлен для: Guest
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
Journal of Environmental Pathology, Toxicology and Oncology
Импакт фактор: 1.241 5-летний Импакт фактор: 1.349 SJR: 0.356 SNIP: 0.613 CiteScore™: 1.61

ISSN Печать: 0731-8898
ISSN Онлайн: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.v25.i1-2.220
pages 341-372

Fluorescence Diagnosis Using Enzyme-Related Metabolic Abnormalities of Neoplasia

Marino A. Campo
School of Pharmaceutical Sciences, University of Geneva, 30, Quai Ernest Ansermet, CH-1211 Geneva, Switzerland
Norbert Lange
School of Pharmaceutical Sciences, University of Geneva, 30, Quai Ernest Ansermet, CH-1211 Geneva, Switzerland

Краткое описание

Early cancer diagnosis is of the most crucial factors determining proper patient management and long-term survival. Thus, there is considerable interest in developing more reliable methods for cancer diagnosis. Fluorescence diagnosis using metabolic alterations of neoplasia has emerged as a powerful new biomedical tool. It is characterized by superior sensitivity and selectivity over other methods, and it offers the possibility to obtain molecular information required to determine the state of the disease. Furthermore, important advancements have been made in generating deeper three-dimensional images in vivo by exploiting tissue transparency in the near-infrared region and fluorescence-mediated tomography, which might render fluorescence diagnosis less invasive. From basic principles in optics and molecular biology to the development of medical instrumentation and the launching of clinical trials, we have comprehensively compiled the basic information required to clearly understand fundamental aspects of fluorescence-based diagnosis.

Articles with similar content:

Pediatric Rhabdomyosarcoma
Critical Reviews™ in Oncogenesis, Vol.20, 2015, issue 3-4
Jack F. Shern, Marielle E. Yohe, Javed Khan
Newer Trends in Pancreatic Cancer Treatment: Genetic Alterations and the Role of Immune Therapeutic and Targeted Therapies
Critical Reviews™ in Oncogenesis, Vol.24, 2019, issue 2
Abdul Kareem Khan, Mamoon Ur Rashid, Ishtiaq Hussain, Sarfraz Ahmad, Hasan Badar, Muhammad Muzammil, Sundas Jehanzeb, Deepika Sarvepalli, Muhammad Talha Khan, Asad ur Rahman, Waqas Ullah
Targeting of EPH Receptor Tyrosine Kinases for Anticancer Therapy
Critical Reviews™ in Oncogenesis, Vol.17, 2012, issue 2
Martin Lackmann, Eva Nievergall, Thomas Saunders
Positron Emission Tomography Imaging of Tumor Response after Photodynamic Therapy
Journal of Environmental Pathology, Toxicology and Oncology, Vol.25, 2006, issue 1-2
Johan E. van Lier, Veronique Berard, Roger Lecomte
Role of the Progesterone Receptor (PR) and the PR Isoforms in Breast Cancer
Critical Reviews™ in Oncogenesis, Vol.13, 2007, issue 4
Orla Mc Cormack, Michael J. Kerin, Amanda McCann, Michele Harrison