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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
Journal of Long-Term Effects of Medical Implants
SJR: 0.145 SNIP: 0.491 CiteScore™: 0.89

ISSN Печать: 1050-6934
ISSN Онлайн: 1940-4379

Выпуски:
Том 30, 2020 Том 29, 2019 Том 28, 2018 Том 27, 2017 Том 26, 2016 Том 25, 2015 Том 24, 2014 Том 23, 2013 Том 22, 2012 Том 21, 2011 Том 20, 2010 Том 19, 2009 Том 18, 2008 Том 17, 2007 Том 16, 2006 Том 15, 2005 Том 14, 2004 Том 13, 2003 Том 12, 2002 Том 11, 2001 Том 10, 2000

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v16.i1.50
pages 41-49

Anterior Cruciate Reconstruction with Bioactive Leeds-Keio Ligament (LKII): Preliminary Report

Atsushi Sugihara
Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan
Kyosuke Fujikawa
Knee Disease Centre, Ohtsuki Hospital for Surgery, Tokyo; Professor of Orthopaedic Surgery. Department of Orthopredic Surgery National Defense Medical College, Saitama, Japan
Hironobu Watanabe
Department of Orthopaedic Surgery, Self Defense Force Sasebo Hospital, Nagasaki, Japan
Hideaki Murakami
Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan
Toshiyuki Kikuchi
Department of Orthopaedic Surgery, National Defense Medical Collage, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan
Satoshi Tsukazaki
Department of Orthopaedic Surgery, National Defense Medical Collage, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan
Yoshihiro Aoki
Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan
Masashi Matsunaga
Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan
Koichi Nemoto
Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan

Краткое описание

The scaffold type Leeds-Keio artificial ligament (LK) for ligament reconstruction of the knee provides sufficient strength to require minimal sacrifice of autogenous tissue. This implant works not only as prosthesis but also as scaffold onto which natural tissue grows from the synovium. LK has been in clinical use for anterior cruciate ligament (ACL) reconstruction since 1982, although the operative procedure has been modified and has undergone significant development since that time. Recently, we developed radio frequency-generated glow discharge (RFGGD)-treated LK ligament (LKII, previously indicated as Bio-LK) to improve tissue induction and reported that cell proliferation and cell attachment to artificial fibers increased considerably with this hydrophilic treatment. In this study, we report the findings of reconstructed ACL using LKII, which has been in clinical use since 2003. At reconstruction, LKII was covered with the remnant of the original ACL as much as possible in order to preserve the nerve ending system. Thirteen cases with over 12 months' postoperative history were reviewed. Knee stability was regained after reconstruction without any complications such as joint effusion and chronic synovitis. In one case, postoperative arthroscopy showed that the reconstructed ACL was completely covered with newly formed tissue at 8 weeks postoperatively. Biopsy revealed abundant fibroblasts, collagenous fibers, and vessels around the artificial fibers without marked inflammatory findings. Transmission electron microscope study showed abundant thin collagen fibers, which demonstrated regular orientation to some extent. Fibroblasts were observed with extensive amount of rough endoplasmic reticulum. According to these results, we consider LKII to be superior to LK in tissue induction and maturation.


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