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Journal of Long-Term Effects of Medical Implants
Главный редактор: Subrata Saha (open in a new tab)

Выходит 4 номеров в год

ISSN Печать: 1050-6934

ISSN Онлайн: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

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Fibrin Sealant Reduces Perioperative Blood Loss in Total Hip Replacement

Том 13, Выпуск 5, 2003, 14 pages
DOI: 10.1615/JLongTermEffMedImplants.v13.i5.50
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Краткое описание

Patients (n = 81) undergoing total hip replacement (THR) were randomized to receive either standard of care plus fibrin sealant (FS) (10 mL total) or standard of care alone to evaluate the efficacy of FS for reducing blood loss in THR. Considering the 81 intent-to-treat patients, adjusted perioperative blood loss was reduced significantly in the FS group, by 197 mL [95% CI: 45 mL, 319 mL] or 23.5% [95% CI: 5.4%, 38.1%] (p = 0.014). When protocol violators were eliminated, leaving 73 patients, the adjusted FS group perioperative bleeding was reduced by 221 mL [95% CI: 63 mL, 351 mL] or 27.1% [95% CI: 7.6%, 42.5%] (p = 0.0098).

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