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ISSN Печать: 1050-6934
ISSN Онлайн: 1940-4379
Indexed in
On the Bending Properties of Porcine Mitral, Tricuspid, Aortic, and Pulmonary Valve Leaflets
Краткое описание
The atrioventricular valve leaflets (mitral and tricuspid) are different from the semilunar valve leaflets (aortic and pulmonary) in layered structure, ultrastructural constitution and organization, and leaflet thickness. These differences warrant a comparative look at the bending properties of the four types of leaflets. We found that the moment−curvature relationships in atrioventricular valves were stiffer than in semilunar valves, and the moment−curvature relationships of the left-side valve leaflets were stiffer than their morphological analog of the right side. These trends were supported by the moment−curvature curves and the flexural rigidity analysis (EI value decreased from mitral, tricuspid, aortic, to pulmonary leaflets). However, after taking away the geometric effect (moment of inertia I), the instantaneous effective bending modulus E showed a reversed trend. The overall trend of flexural rigidity (EI: mitral > tricuspid > aortic > pulmonary) might be correlated with the thickness variations among the four types of leaflets (thickness: mitral > tricuspid > aortic > pulmonary). The overall trend of the instantaneous effective bending modulus (E: mitral < tricuspid < aortic < pulmonary) might be correlated to the layered fibrous ultrastructures of the four types of leaflets, of which the fibers in mitral and tricuspid leaflets were less aligned, and the fibers in aortic and pulmonary leaflets were highly aligned. We also found that, for all types of leaflets, moment−curvature relationships are stiffer in against-curvature (AC) bending than in with-curvature bending (WC), which implies that leaflets tend to flex toward their natural curvature and comply with blood flow. Lastly, we observed that the leaflets were stiffer in circumferential bending compared with radial bending, likely reflecting the physiological motion of the leaflets, i.e., more bending moment and movement were experienced in radial direction than circumferential direction.
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Lee Chung-Hao, Laurence Devin W., Ross Colton J., Kramer Katherine E., Babu Anju R., Johnson Emily L., Hsu Ming-Chen, Aggarwal Ankush, Mir Arshid, Burkhart Harold M., Towner Rheal A., Baumwart Ryan, Wu Yi, Mechanics of the Tricuspid Valve—From Clinical Diagnosis/Treatment, In-Vivo and In-Vitro Investigations, to Patient-Specific Biomechanical Modeling, Bioengineering, 6, 2, 2019. Crossref
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Liao Jun, Sacks Michael S., On the Unique Functional Elasticity and Collagen Fiber Kinematics of Heart Valve Leaflets, in Advances in Heart Valve Biomechanics, 2018. Crossref
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Copeland Katherine M., Wang Bo, Shi Xiaodan, Simionescu Dan T., Hong Yi, Bajona Pietro, Sacks Michael S., Liao Jun, Decellularization in Heart Valve Tissue Engineering, in Advances in Heart Valve Biomechanics, 2018. Crossref
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Kodigepalli Karthik M., Thatcher Kaitlyn, West Toni, Howsmon Daniel P., Schoen Frederick J., Sacks Michael S., Breuer Christopher K., Lincoln Joy, Biology and Biomechanics of the Heart Valve Extracellular Matrix, Journal of Cardiovascular Development and Disease, 7, 4, 2020. Crossref
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Ambrosi D., Deorsola L., Turzi S., Zoppello M., Elementary Mechanics of the Mitral Valve, SIAM Journal on Applied Mathematics, 82, 1, 2022. Crossref
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Anssari-Benam Afshin, Horgan Cornelius O., New results in the theory of plane strain flexure of incompressible isotropic hyperelastic materials, Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 478, 2258, 2022. Crossref
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Deepak Thirumalai, Yamini Patina, Babu Anju R., Biomechanics of the Aortic Valve in Health and Disease, in Advances in Computational Approaches in Biomechanics, 2022. Crossref
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Pham Thuy, Sulejmani Fatiesa, Shin Erica, Wang Di, Sun Wei, Quantification and comparison of the mechanical properties of four human cardiac valves, Acta Biomaterialia, 54, 2017. Crossref