Выходит 6 номеров в год
ISSN Печать: 1040-8401
ISSN Онлайн: 2162-6472
IF:
1.3
5-Year IF:
2.6
Eigenfactor:
0.00079
JCI:
0.24
SJR:
0.429
SNIP:
0.287
CiteScore™::
2.7
H-Index:
81
Indexed in
Mechanisms of Cytotoxic Lymphocyte-Mediated Apoptosis and Relationship with the Tumor Suppressor p53
Get access
Краткое описание
Cytotoxic T lymphocytes and natural killer cells are key effector cells in the immune response against intracellular infection and transformed cells. These killer cells induce multiple programs of cell death to achieve their function of eliminating their targets. In this review, we summarize our current understanding of the signaling pathways involved in target cells apoptosis triggered by the cytotoxic effector cells. We also discuss the role of an important player in the field of apoptosis, the well-known p53 tumor suppressor, in the modulation of cytotoxic lymphocyte-mediated cell death.
-
Mukherjee Sumit, Baidoo Juliet, Sampat Samay, Mancuso Andrew, David Lovena, Cohen Leah, Zhou Shuiqin, Banerjee Probal, Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells, Molecules, 23, 1, 2018. Crossref
-
Chollat-Namy Marie, Ben Safta-Saadoun Thouraya, Haferssas Djazia, Meurice Guillaume, Chouaib Salem, Thiery Jerome, The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy, Cell Death & Disease, 10, 10, 2019. Crossref
-
Guo Xiaocan, Zhao Yang, Yan Huan, Yang Yingcheng, Shen Shuying, Dai Xiaoming, Ji Xinyan, Ji Fubo, Gong Xing-Guo, Li Li, Bai Xueli, Feng Xin-Hua, Liang Tingbo, Ji Junfang, Chen Lei, Wang Hongyang, Zhao Bin, Single tumor-initiating cells evade immune clearance by recruiting type II macrophages, Genes & Development, 31, 3, 2017. Crossref