Выходит 6 номеров в год
ISSN Печать: 1040-8401
ISSN Онлайн: 2162-6472
Indexed in
Lymphocyte Adhesion to Endothelium
Краткое описание
The different homing and recirculation behaviors of lymphocytes depend on expression of specific adhesion receptors by lymphocytes and endothelial cells. Expression of these receptors is finely regulated according to cell type, functional state, and anatomical location, and builds up a complex network of interactions that simultaneously involve several of these receptors working as "traffic signals" or "postcodes" for lymphocyte migration and homing. There are five main families of adhesion molecules: immunoglobulin superfamily, integrins, selectins, cadherins, and mucin-like molecules. Together with these "classified" receptors, other molecules, such as CD44 and CD38, have been shown to be involved in lymphocyte migration and homing. Leukocytes have evolved a intracellular system that allows them to maintain these receptors in an inactive state during transit in the bloodstream and extracellular fluids and activate them only when proper specific stimuli are delivered. This activity has been called "inside-out" signaling. Most receptor/ligand systems regulating lymphocyte migration are not selectively dedicated to this function. They are involved in lymphocyte interaction with several cell types and play a key role in both the afferent and efferent branches of immune responses by mediating lymphocyte interaction with APC and target cells. They not only "passively" anchor lymphocytes to these cells but also exert an active "outside-in" signaling function that modulates the cell response to activation stimuli. In this review, we briefly describe the major features of these molecules, survey what is known about their role in lymphocyte/endothelium interactions both in vitro and in vivo, and discuss their possible therapeutical application.
-
Oviedo-orta E., Hoy T., Evans W. H., Intercellular communication in the immune system: differential expression of connexin40 and 43, and perturbation of gap junction channel functions in peripheral blood and tonsil human lymphocyte subpopulations, Immunology, 99, 4, 2000. Crossref
-
Shirpoor Alireza, Khadem Ansari Mohammad-Hasan, Heshmatian Behnam, Ilkhanizadeh Behrouz, Noruzi Leila, Abdollahzadeh Naseh, Saboory Ehsan, Decreased blood pressure with a corresponding decrease in adhesive molecules in diabetic rats caused by vitamin E administration, Journal of Diabetes, 4, 4, 2012. Crossref
-
Parish Christopher R, Hindmarsh Elizabeth J, Bartlett Mark R, Staykova Maria A, Cowden William B, Willenborg David O, Treatment of central nervous system inflammation with inhibitors of basement membrane degradation, Immunology and Cell Biology, 76, 1, 1998. Crossref
-
SAVILAHTI E, ÖRMÄLÄ T, SAUKKONEN T, SANDINI-POHJAVUORI U, KANTELE J M, ARATO A, ILONEN J, ÅKERBLOM H K, Jejuna of patients with insulin-dependent diabetes mellitus (IDDM) show signs of immune activation, Clinical and Experimental Immunology, 116, 1, 2001. Crossref
-
Indumathi S., Harikrishnan R., Rajkumar J. S., Dhanasekaran M., Immunophenotypic comparison of heterogenous non-sorted versus sorted mononuclear cells from human umbilical cord blood: a novel cell enrichment approach, Cytotechnology, 67, 1, 2015. Crossref
-
Zhao Hong, Dong Xi, Wang Xiong, Li Xiufeng, Zhuang Fengyuan, Stoltz Jean François, Lou Jinning, Studies on Single-Cell Adhesion Probability between Lymphocytes and Endothelial Cells with Micropipette Technique, Microvascular Research, 63, 2, 2002. Crossref
-
Buonfiglio Donatella, Bragardo Manuela, Bonissoni Sara, Redoglia Valter, Cauda Roberto, Zupo Simona, Burgio Vito L., Wolff Henrik, Franssila Kaarle, Gaidano Gianluca, Carbone Antonino, Janeway Jr Charles A., Dianzani Umberto, Characterization of a novel human surface molecule selectively expressed by mature thymocytes, activated T cells and subsets of T cell lymphomas, European Journal of Immunology, 29, 9, 1999. Crossref
-
Ricard Isabelle, Payet Marcel D., Dupuis Gilles, Clustering the adhesion molecules VLA-4 (CD49d/CD29) in Jurkat T cells or VCAM-1 (CD106) in endothelial (ECV 304) cells activates the phosphoinositide pathway and triggers Ca2+ mobilization, European Journal of Immunology, 27, 6, 1997. Crossref
-
Galle Cécile, De Maertelaer Viviane, Motte Serge, Zhou Ling, Stordeur Patrick, Delville Jean-Pierre, Li Rong, Ferreira José, Goldman Michel, Capel Paul, Wautrecht Jean-Claude, Pradier Olivier, Dereume Jean-Pierre, Early inflammatory response after elective abdominal aortic aneurysm repair: A comparison between endovascular procedure and conventional surgery, Journal of Vascular Surgery, 32, 2, 2000. Crossref
-
Quarona Valeria, Zaccarello Gianluca, Chillemi Antonella, Brunetti Enrico, Singh Vijay Kumar, Ferrero Enza, Funaro Ada, Horenstein Alberto L., Malavasi Fabio, CD38 and CD157: A long journey from activation markers to multifunctional molecules, Cytometry Part B: Clinical Cytometry, 84B, 4, 2013. Crossref
-
JUNGHEIM K., USADEL K.H., CASPAR G., SCHUMM-DRAEGER P.M., Immunologic Effects of Human Peripheral and Intrathyroidal Lymphocytes on Xenotransplanted Human Thyroid Tissue in Athymic Nude Mice, Thyroid, 9, 1, 1999. Crossref
-
Alexander J. Steven, Elrod John, Park Jae, Roles of Leukocyte and Immune Cell Junctional Proteins, Microcirculation, 8, 3, 2001. Crossref
-
Jungheim K., Caspar G., Usadel K.H., Schumm-Draeger P.M., Expression of Intracellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 and Homing Factor CD44 After Engraftment of Graves' Lymphocytes in Xenotransplanted Human Thyroid Tissue in Athymic Nude Mice, Thyroid, 11, 9, 2001. Crossref
-
Jungheim K., Caspar G., Usadel K.H., Schumm-Draeger P.M., Lymphocyte Homing in Xenotransplanted Human Thyroid Tissue Can Be Inhibited by LFA-1 and ICAM-1 Antibodies, Thyroid, 14, 1, 2004. Crossref
-
Cruse Julius M., Keith John C., Bryant M. Lamar, Lewis Robert E., Immune system-neuroendocrine dysregulation in spinal cord injury, Immunologic Research, 15, 4, 1996. Crossref
-
SAKAGUCHI Ikuyo, TSUJIMURA Masae, IKEDA Norikazu, MINAMINO Miki, KATO Yoshiko, WATABE Kazuhito, YANO Ikuya, KANEDA Kenji, Granulomatous Tissue Formation of Shikon and Shikonin by Air Pouch Method., Biological and Pharmaceutical Bulletin, 24, 6, 2001. Crossref
-
Liu Zhiyuan, Cumberland William G., Hultin Lance E., Prince Harry E., Detels Roger, Giorgi Janis V., Elevated CD38 Antigen Expression on CD8+ T Cells Is a Stronger Marker for the Risk of Chronic HIV Disease Progression to AIDS and Death in the Multicenter AIDS Cohort Study Than CD4+ Cell Count, Soluble Immune Activation Markers, or Combinations of HLA-DR and CD38 Expression, Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 16, 2, 1997. Crossref
-
Galland Franck, Malergue Fabrice, Bazin Hermine, Mattei Marie Geneviève, Aurrand-Lions Michel, Theillet Charles, Naquet Philippe, Two Human Genes Related to Murine Vanin-1 Are Located on the Long Arm of Human Chromosome 6, Genomics, 53, 2, 1998. Crossref
-
Zhao Yong, Huang Zhihua, Qi Meirigeng, Lazzarini Ping, Mazzone Theodore, Immune regulation of T lymphocyte by a newly characterized human umbilical cord blood stem cell, Immunology Letters, 108, 1, 2007. Crossref
-
Deaglio Silvia, Canella Donatella, Baj Germano, Arnulfo Alberto, Waxman Samuel, Malavasi Fabio, Evidence of an immunologic mechanism behind the therapeutical effects of arsenic trioxide (As2O3) on myeloma cells, Leukemia Research, 25, 3, 2001. Crossref
-
Brayton John, Qing Zhu, Hart Michael N, VanGilder John C, Fabry Zsuzsa, Influence of adhesion molecule expression by human brain microvessel endothelium on cancer cell adhesion, Journal of Neuroimmunology, 89, 1-2, 1998. Crossref
-
Zoeller M., CD44v10 in Hematopoiesis and Stem Cell Mobilization, Leukemia & Lymphoma, 38, 5-6, 2000. Crossref
-
Oshima Tadayuki, Blaschuk Orest, Gour Barbara, Symonds Matt, Elrod John W, Sasaki Makotoh, Jackson T.Haller, Alexander J.Steven, Tight junction peptide antagonists enhance neutrophil trans-endothelial chemotaxis, Life Sciences, 73, 13, 2003. Crossref
-
Dunky Attila, Neumüller Josef, Menzel Johannes, Interactions of Lymphocytes from Patients with Psoriatic Arthritis or Healthy Controls and Cultured Endothelial Cells, Clinical Immunology and Immunopathology, 85, 3, 1997. Crossref
-
Rankin James A., Biological Mediators of Acute Inflammation, AACN Clinical Issues: Advanced Practice in Acute and Critical Care, 15, 1, 2004. Crossref
-
Shubinsky George, Schlesinger Michael, The CD38 Lymphocyte Differentiation Marker: New Insight into Its Ectoenzymatic Activity and Its Role as a Signal Transducer, Immunity, 7, 3, 1997. Crossref
-
Matsumiya Tomoh, Imaizumi Tadaatsu, Fujimoto Koji, Cui Xuefan, Shibata Takeo, Tamo Wakako, Kumagai Mika, Tanji Kunikazu, Yoshida Hidemi, Kimura Hiroto, Satoh Kei, Soluble Interleukin-6 Receptor α Inhibits the Cytokine-Induced Fractalkine/CX3CL1 Expression in Human Vascular Endothelial Cells in Culture, Experimental Cell Research, 269, 1, 2001. Crossref
-
Costacou Tina, Lopes-Virella Maria F., Zgibor Janice C., Virella Gabriel, Otvos Jim, Walsh Michael, Orchard Trevor J., Markers of endothelial dysfunction in the prediction of coronary artery disease in Type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study, Journal of Diabetes and its Complications, 19, 4, 2005. Crossref
-
Cruse J.M., Lewis R.E., Roe D.L., Dilioglou S., Blaine M.C., Wallace W.F., Chen R.S., Facilitation of Immune Function, Healing of Pressure Ulcers, and Nutritional Status in Spinal Cord Injury Patients, Experimental and Molecular Pathology, 68, 1, 2000. Crossref
-
Minelli R, Serpe L, Pettazzoni P, Minero V, Barrera G, Gigliotti CL, Mesturini R, Rosa AC, Gasco P, Vivenza N, Muntoni E, Fantozzi R, Dianzani U, Zara GP, Dianzani C, Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells, British Journal of Pharmacology, 166, 2, 2012. Crossref
-
Harcourt Brian H., Sanchez Anthony, Offermann Margaret K., Ebola Virus Inhibits Induction of Genes by Double-Stranded RNA in Endothelial Cells, Virology, 252, 1, 1998. Crossref
-
Kalnina Inta, Kirilova Elena, Klimkane Laura, Kirilov Georgii, Altered plasma albumin characteristics and lymphocyte populations in gastrointestinal cancer patients: Detection using modified fluorescence responses, Journal of Immunotoxicology, 6, 4, 2009. Crossref
-
Khan Manzoor M., Overview of the Immune Response, in Immunopharmacology, 2016. Crossref
-
Savarino Andrea, Bottarel Flavia, Malavasi Fabio, Dianzani Umberto, Role of CD38 in HIV-1 infection: an epiphenomenon of T-cell activation or an active player in virus/host interactions?, AIDS, 14, 9, 2000. Crossref
-
Mandyam Chitra, Villalpando Emmanuel, Steiner Noah, Quach Leon, Fannon McKenzie, Somkuwar Sucharita, Platelet Endothelial Cell Adhesion Molecule-1 and Oligodendrogenesis: Significance in Alcohol Use Disorders, Brain Sciences, 7, 12, 2017. Crossref
-
Suscovich Todd J, Paulose-Murphy Mini, Harlow Jason D, Chen Yidong, Thomas Seddon Y, Mellott Tiffany J, Walker Bruce D, Scadden David T, Zeichner Steven, Brander Christian, Defective Immune Function of Primary Effusion Lymphoma Cells is Associated with Distinct KSHV Gene Expression Profiles, Leukemia & Lymphoma, 45, 6, 2004. Crossref
-
Petersen Frank, Bock Lothar, Flad Hans-Dieter, Brandt Ernst, Platelet Factor 4-Induced Neutrophil-Endothelial Cell Interaction: Involvement of Mechanisms and Functional Consequences Different From Those Elicited by Interleukin-8, Blood, 94, 12, 1999. Crossref
-
Yoneda Osamu, Imai Toshio, Goda Seiji, Inoue Hiroshi, Yamauchi Akira, Okazaki Toshio, Imai Hisao, Yoshie Osamu, Bloom Eda T., Domae Naochika, Umehara Hisanori, Fractalkine-Mediated Endothelial Cell Injury by NK Cells, The Journal of Immunology, 164, 8, 2000. Crossref
-
Zannettino Andrew C.W., Bühring Hans-Jörg, Niutta Silvana, Watt Suzanne M., Benton M. Ann, Simmons Paul J., The Sialomucin CD164 (MGC-24v) Is an Adhesive Glycoprotein Expressed by Human Hematopoietic Progenitors and Bone Marrow Stromal Cells That Serves as a Potent Negative Regulator of Hematopoiesis, Blood, 92, 8, 1998. Crossref
-
Goda Seiji, Imai Toshio, Yoshie Osamu, Yoneda Osamu, Inoue Hiroshi, Nagano Yutaka, Okazaki Toshiro, Imai Hisao, Bloom Eda T., Domae Naochika, Umehara Hisanori, CX3C-Chemokine, Fractalkine-Enhanced Adhesion of THP-1 Cells to Endothelial Cells Through Integrin-Dependent and -Independent Mechanisms, The Journal of Immunology, 164, 8, 2000. Crossref
-
Avanzi Gian Carlo, Gallicchio Margherita, Bottarel Flavia, Gammaitoni Loretta, Cavalloni Giuliana, Buonfiglio Donatella, Bragardo Manuela, Bellomo Giorgio, Albano Emanuele, Fantozzi Roberto, Garbarino Giovanni, Varnum Brian, Aglietta Massimo, Saglio Giuseppe, Dianzani Umberto, Dianzani Chiara, GAS6 Inhibits Granulocyte Adhesion to Endothelial Cells, Blood, 91, 7, 1998. Crossref
-
Chillemi Antonella, Zaccarello Gianluca, Quarona Valeria, Ferracin Manuela, Ghimenti Chiara, Massaia Massimo, Horenstein Alberto L., Malavasi Fabio, Anti-CD38 Antibody Therapy: Windows of Opportunity Yielded by the Functional Characteristics of the Target Molecule, Molecular Medicine, 19, 1, 2013. Crossref
-
Khan Manzoor M., Overview of the Immune Response, in Immunopharmacology, 2008. Crossref
-
Zannettino Andrew C.W., Bühring Hans-Jörg, Niutta Silvana, Watt Suzanne M., Benton M. Ann, Simmons Paul J., The Sialomucin CD164 (MGC-24v) Is an Adhesive Glycoprotein Expressed by Human Hematopoietic Progenitors and Bone Marrow Stromal Cells That Serves as a Potent Negative Regulator of Hematopoiesis, Blood, 92, 8, 1998. Crossref
-
Botella Luisa M., Puig-Kröger Amaya, Almendro Nuria, Sánchez-Elsner Tilman, Muñoz Eduardo, Corbí Angel, Bernabéu Carmelo, Identification of a Functional NF-κB Site in the Platelet Endothelial Cell Adhesion Molecule-1 Promoter, The Journal of Immunology, 164, 3, 2000. Crossref
-
Petersen Frank, Bock Lothar, Flad Hans-Dieter, Brandt Ernst, Platelet Factor 4-Induced Neutrophil-Endothelial Cell Interaction: Involvement of Mechanisms and Functional Consequences Different From Those Elicited by Interleukin-8, Blood, 94, 12, 1999. Crossref
-
Avanzi Gian Carlo, Gallicchio Margherita, Bottarel Flavia, Gammaitoni Loretta, Cavalloni Giuliana, Buonfiglio Donatella, Bragardo Manuela, Bellomo Giorgio, Albano Emanuele, Fantozzi Roberto, Garbarino Giovanni, Varnum Brian, Aglietta Massimo, Saglio Giuseppe, Dianzani Umberto, Dianzani Chiara, GAS6 Inhibits Granulocyte Adhesion to Endothelial Cells, Blood, 91, 7, 1998. Crossref
-
Lang Stephan, Lauffer Lina, Clausen Christoph, Löhr Iren, Schmitt Bärbel, Hölzel Dieter, Wollenberg Barbara, Gires Olivier, Kastenbauer Ernst, Zeidler Reinhard, Impaired monocyte function in cancer patients: restoration with a cyclooxygenase‐2 inhibitor, The FASEB Journal, 17, 2, 2003. Crossref
-
References, in HIV and the Pathogenesis of AIDS, 2014. Crossref
-
Prakobphol Akraporn, Tangemann Kirsten, Rosen Steven D., Hoover Charles I., Leffler Hakon, Fisher Susan J., Separate Oligosaccharide Determinants Mediate Interactions of the Low-Molecular-Weight Salivary Mucin with Neutrophils and Bacteria, Biochemistry, 38, 21, 1999. Crossref
-
Deaglio Silvia, Malavasi Fabio, The CD38/CD157 mammalian gene family: An evolutionary paradigm for other leukocyte surface enzymes, Purinergic Signalling, 2, 2, 2006. Crossref
-
Amirghofran Zahra, Jalali Seyed Amir, Hosseini Seyed Vahid, Vasei Mohammad, Sabayan Behnam, Ghaderi Abbas, Evaluation of CD44 and CD44v6 in Colorectal Carcinoma Patients: Soluble Forms in Relation to Tumor Tissue Expression and Metastasis, Journal of Gastrointestinal Cancer, 39, 1-4, 2008. Crossref
-
Joher Nizar, Matignon Marie, Grimbert Philippe, HLA Desensitization in Solid Organ Transplantation: Anti-CD38 to Across the Immunological Barriers, Frontiers in Immunology, 12, 2021. Crossref
-
Lejtenyi Duncan, Osmond Dennis G., Miller Sandra C., Natural killer cells and B lymphocytes in L-selectin and Mac-1/LFA-1 knockout mice: marker-dependent, but not cell lineage-dependent changes in the spleen and bone marrow, Immunobiology, 207, 2, 2003. Crossref
-
Rösel Marc, Khaldoyanidi Sophia, Zawadzki Volker, Zöller Margot, Involvement of CD44 variant isoform v10 in progenitor cell adhesion and maturation, Experimental Hematology, 27, 4, 1999. Crossref
-
Messud-Petit Frederique, Gelfi Jacqueline, Delverdier Maxence, Amardeilh Marie-France, Py Robert, Sutter Gerd, Bertagnoli Stephane, Serp2, an Inhibitor of the Interleukin-1β-Converting Enzyme, Is Critical in the Pathobiology of Myxoma Virus, Journal of Virology, 72, 10, 1998. Crossref
-
Harcourt Brian H., Sanchez Anthony, Offermann Margaret K., Ebola Virus Selectively Inhibits Responses to Interferons, but Not to Interleukin-1β, in Endothelial Cells, Journal of Virology, 73, 4, 1999. Crossref
-
Ro Young-Tae, Patterson Jean L., Transcriptional induction of TGF-β1 and endothelial-to-mesenchymal transition cell markers in human umbilical vein endothelial cells by Ebola virus infection, Genes & Genomics, 44, 12, 2022. Crossref