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Critical Reviews™ in Immunology

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ISSN Печать: 1040-8401

ISSN Онлайн: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

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Mechanisms That Contribute to the Development of Lymphoid Malignancies: Roles for Genetic Alterations and Cytokine Production

Том 16, Выпуск 1, 1996, pp. 31-57
DOI: 10.1615/CritRevImmunol.v16.i1.30
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Краткое описание

Recent studies have defined genetic alterations commonly associated with transformed lymphocytes. This review suggests roles for these alterations in the development of lymphoid neoplasms. Damage to the genes encoding proteins that function in intracellular signaling, transcription, or regulation of the cell cycle has been identified and linked at varying degrees to the progression of certain lymphoid malignancies. An understanding of the mechanistic consequences following such genetic alterations is essential to an understanding of the development of these lymphoid neoplasms. In contrast, it is also becoming clear that the dysregulated expression of proteins that are not genetically altered can also contribute to the progression of lymphoid malignancies. One such example is the excessive expression of "normal" lymphokines or cytokines which accompanies many lymphoproliferative diseases. The dysregulated expression of cytokines during malignancy can result in the augmentation of growth of transformed lymphocytes, as well as an alteration of the anti-tumor immune response. The latter mechanism is especially important because evasion of the impending immune response is a prerequisite for the progression of lymphoproliferative diseases. Taken together, this review supports the notion that the development of lymphoid malignancies is multifactorial, involving genetic alterations as well as dysregulated cytokine expression.

Ключевые слова: lymphokines, T helper cells, anti-tumor immunity.
ЦИТИРОВАНО В
  1. Ho Joanna W. Y., Liang Raymond H. S., Srivastava Gopesh, Preferential type 1-1 cytokine gene expressions in peripheral T-cell lymphomas, Hematological Oncology, 17, 3, 1999. Crossref

  2. Martini Fernanda, Dolcetti Riccardo, Gloghini Annunziata, Iaccheri Laura, Carbone Antonino, Boiocchi Mauro, Tognon Mauro, Simian-virus-40 footprints in human lymphoproliferative disorders of HIV− and HIV+ patients, International Journal of Cancer, 78, 6, 1998. Crossref

  3. Tognon Mauro, Luppi Mario, Corallini Alfredo, Taronna Angelo, Barozzi Patrizia, Rotondo John Charles, Comar Manola, Casali Maria Vittoria, Bovenzi Massimo, D'Agostino Antonio, Vinante Fabrizio, Rigo Antonella, Ferrarini Isacco, Barbanti-Brodano Giuseppe, Martini Fernanda, Mazzoni Elisa, Immunologic evidence of a strong association between non-Hodgkin lymphoma and simian virus 40, Cancer, 121, 15, 2015. Crossref

  4. Langie Sabine A.S., Koppen Gudrun, Desaulniers Daniel, Al-Mulla Fahd, Al-Temaimi Rabeah, Amedei Amedeo, Azqueta Amaya, Bisson William H., Brown Dustin, Brunborg Gunnar, Charles Amelia K., Chen Tao, Colacci Annamaria, Darroudi Firouz, Forte Stefano, Gonzalez Laetitia, Hamid Roslida A., Knudsen Lisbeth E., Leyns Luc, Lopez de Cerain Salsamendi Adela, Memeo Lorenzo, Mondello Chiara, Mothersill Carmel, Olsen Ann-Karin, Pavanello Sofia, Raju Jayadev, Rojas Emilio, Roy Rabindra, Ryan Elizabeth, Ostrosky-Wegman Patricia, Salem Hosni K., Scovassi A.Ivana, Singh Neetu, Vaccari Monica, Van Schooten Frederik J., Valverde Mahara, Woodrick Jordan, Zhang Luoping, van Larebeke Nik, Kirsch-Volders Micheline, Collins Andrew R., Causes of genome instability: the effect of low dose chemical exposures in modern society, Carcinogenesis, 36, Suppl 1, 2015. Crossref

  5. Rousseau Raphaël F., Hirschmann-Jax Charlotte, Takahashi Satoshi, Brenner Malcolm K., CANCER VACCINES, Hematology/Oncology Clinics of North America, 15, 4, 2001. Crossref

  6. Beaty R.M., Rulli K., Bost K.L., Pantginis J., Lenz J., Levy L.S., High Levels of IL-4 and IL-10 mRNA and Low Levels of IL-2, IL-9 and IFN-γ mRNA in MuLV-Induced Lymphomas, Virology, 261, 2, 1999. Crossref

  7. Villunger Andreas, Strasser Andreas, The great escape: Is immune evasion required for tumor progression?, Nature Medicine, 5, 8, 1999. Crossref

  8. Somasundaram Rajasekharan, Zhang Tianqian, Herlyn Dorothee, Analysis of Humoral Immune Responses in Vaccine Trials, in Handbook of Cancer Vaccines, 2004. Crossref

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