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ISSN Печать: 1040-8401
ISSN Онлайн: 2162-6472
Indexed in
Expression of Inhibitory Receptors for MHC Class I Molecules on T Cells
Краткое описание
Inhibitory receptors (IRs) specific for MHC class I molecules and originally described on natural killer (NK) cells are also expressed on a fraction of peripheral T cells. The presence of these receptors on T cells is poorly understood. In this review, the different antigen specificities described to date for IR+ T cells and the expression pattern of these receptors on T cells are analyzed. This analysis indicates that the population of T cells defined by IR expression is heterogeneous and that different IRs (or families of IRs) may play different roles in T-cell biology.
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Arlettaz Lionel, Villard Jean, de Rham Casimir, Degermann Sylvie, Chapuis Bernard, Huard Bertrand, Roosnek Eddy, Activating CD94:NKG2C and inhibitory CD94:NKG2A receptors are expressed by distinct subsets of committed CD8+ TCR ?? lymphocytes, European Journal of Immunology, 34, 12, 2004. Crossref
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Iliopoulou Eleni G., Karamouzis Michalis V., Missitzis Ioannis, Ardavanis Alexandros, Sotiriadou Nectaria N., Baxevanis Constantin N., Rigatos Gerasimos, Papamichail Michael, Perez Sonia A., Increased Frequency of CD4+ Cells Expressing CD161 in Cancer Patients, Clinical Cancer Research, 12, 23, 2006. Crossref