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Critical Reviews™ in Therapeutic Drug Carrier Systems
Импакт фактор: 2.9 5-летний Импакт фактор: 3.72 SJR: 0.736 SNIP: 0.551 CiteScore™: 2.43

ISSN Печать: 0743-4863
ISSN Онлайн: 2162-660X

Выпуски:
Том 36, 2019 Том 35, 2018 Том 34, 2017 Том 33, 2016 Том 32, 2015 Том 31, 2014 Том 30, 2013 Том 29, 2012 Том 28, 2011 Том 27, 2010 Том 26, 2009 Том 25, 2008 Том 24, 2007 Том 23, 2006 Том 22, 2005 Том 21, 2004 Том 20, 2003 Том 19, 2002 Том 18, 2001 Том 17, 2000 Том 16, 1999 Том 15, 1998 Том 14, 1997 Том 13, 1996 Том 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v24.i6.20
pages 547-596

Microemulsions: Applications in Transdermal and Dermal Delivery

Abhijit A. Date
Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Santacruz (E.), Mumbai-400 098, India
Vandana B. Patravale
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai, Maharashtra, India

Краткое описание

Microemulsions have gained much interest as second-generation colloidal carrier systems for the dermal/transdermal delivery of the various hydrophilic and lipophilic drugs. The advantages associated with microemulsions include spontaneity of formation, ease of manufacturing, high solubilization capacity, and improved drug stability. This review focuses on the excipients available for the formulation of topical microemulsions and the potential mechanisms responsible for improvements in the dermal/transdermal delivery of therapeutic agents. It also describes the in vitro and in vivo investigations reported for the various classes of therapeutic agents, along with the recent developments.


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