Доступ предоставлен для: Guest
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
Critical Reviews™ in Therapeutic Drug Carrier Systems
Импакт фактор: 2.9 5-летний Импакт фактор: 3.72 SJR: 0.573 SNIP: 0.551 CiteScore™: 2.43

ISSN Печать: 0743-4863
ISSN Онлайн: 2162-660X

Выпуски:
Том 36, 2019 Том 35, 2018 Том 34, 2017 Том 33, 2016 Том 32, 2015 Том 31, 2014 Том 30, 2013 Том 29, 2012 Том 28, 2011 Том 27, 2010 Том 26, 2009 Том 25, 2008 Том 24, 2007 Том 23, 2006 Том 22, 2005 Том 21, 2004 Том 20, 2003 Том 19, 2002 Том 18, 2001 Том 17, 2000 Том 16, 1999 Том 15, 1998 Том 14, 1997 Том 13, 1996 Том 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v27.i5.10
pages 371-417

Cancer Chemotherapy With Lipid-Based Nanocarriers

Donghua Liu
School of Pharmaceutical Science, Shandong University, China
Na Zhang
School of Pharmaceutical Science, Shandong University, China

Краткое описание

Nanotechnology has a profound effect on many areas of scientific research. Having grown exponentially, the focus of nanotechnology has been on therapeutic activity, such as cancer treatment. Lipid-based nanocarriers have attracted increasing scientific and commercial attention in the last few years as alternative carriers for the delivery of anticancer drugs. Lipid-based nanocarriers have played significant roles in the formulation of anticancer drugs to improve therapeutics. Shortcomings frequently encountered with anticancer compounds, such as poor solubility, normal tissue toxicity, poor specificity and stability, as well as the high incidence rate of drug resistance, are expected to be overcome through use of lipid-based nanocarriers. In this review, the advantages and methods of using nanocarriers to improve cancer treatment efficiency will be discussed. In addition, types of lipid-based nanocarriers are presented and hotspots in research are highlighted. It is anticipated that, in the near future, lipid-based nanocarriers will be further improved to deliver cytotoxic anticancer compounds in a more efficient, specific and safe manner.


Articles with similar content:

Role of Block Copolymer Nanoconstructs in Cancer Therapy
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.26, 2009, issue 2
H. G. Agrawal, K. K. Upadhyay, C. Schatz, Sebastian Lecommandoux, J. F. Le Meins, Ambikanandan Misra, C. Upadhyay
Self-Emulsifying Drug Delivery Systems (SEDDS): Formulation Development, Characterization, and Applications
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.26, 2009, issue 5
Shantanu Bandopadhyay, Ramandeep Singh, Bhupinder Singh, Rishi Kapil, Om Parkash Katare
Overview on Therapeutic Applications of Microparticulate Drug Delivery Systems
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.33, 2016, issue 4
Swarna Bale, Mandip Singh, A. Shiva Shankar Reddy, Amit Khurana, Chandraiah Godugu
Current Trends in Self-Emulsifying Drug Delivery Systems (SEDDSs) to Enhance the Bioavailability of Poorly Water-Soluble Drugs
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.33, 2016, issue 1
Rohit Karwal, Tanmay S. Markandeywar, Goutam Rath, Tarun Garg
Lessons Learned from Gemcitabine: Impact of Therapeutic Carrier Systems and Gemcitabine’s Drug Conjugates on Cancer Therapy
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.34, 2017, issue 1
Sathish Dyawanapelly, Animesh Kumar, Manish K. Chourasia