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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
Critical Reviews™ in Therapeutic Drug Carrier Systems
Импакт фактор: 2.9 5-летний Импакт фактор: 3.72 SJR: 0.736 SNIP: 0.551 CiteScore™: 2.43

ISSN Печать: 0743-4863
ISSN Онлайн: 2162-660X

Выпуски:
Том 36, 2019 Том 35, 2018 Том 34, 2017 Том 33, 2016 Том 32, 2015 Том 31, 2014 Том 30, 2013 Том 29, 2012 Том 28, 2011 Том 27, 2010 Том 26, 2009 Том 25, 2008 Том 24, 2007 Том 23, 2006 Том 22, 2005 Том 21, 2004 Том 20, 2003 Том 19, 2002 Том 18, 2001 Том 17, 2000 Том 16, 1999 Том 15, 1998 Том 14, 1997 Том 13, 1996 Том 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.2013007914
pages 1-47

Tiny Technology Proves Big: A Challenge at Engineering, Medicine and Pharmaceutical Sciences Interface

Anjan K. Mahapatra
Department of Pharmaceutical Technology, Maharajah's College of Pharmacy, Vizianagaram, India
P. N. Murthy
Department of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, India
Supriya Samoju
Department of Pharmaceutical Technology, Maharajah's College of Pharmacy, Vizianagaram, India
Aswini K. Mohapatra
Central Institute of Plastic Engineering and Technology, Government of India, Bhubaneswar, India

Краткое описание

Nanoscale materials with a broad spectrum of applications are providing a new foundation for technological integration and innovation. In this article, we review various polymers being used, their polymeric properties, nanoparticle (NP) fabrication, and mechanisms and kinetics of drug release. Specific information is given on each polymer regarding transportation, fate, and delivery issues. Nanoparticles have been developed to deliver conventional drug molecules, peptides and proteins, vaccines, and genes or nucleotides. Nanoparticles have wide application in fields such as cancer therapeutics and targeted drug delivery, including transbarrier brain delivery, dermal and transdermal delivery, intraocular delivery, parenteral delivery, and imaging and diagnostics. In this review, we focus on the potentials of nanotechnology in medicine, and we discuss different nanoparticulate drug delivery systems, including polymeric NPs, metal and metal oxide NPs, ceramics, quantum dots, carbon nanotubes, polymeric micelles, and dendrimers along with their applications in therapeutics, imaging, and diagnostics. In addition, we identify several interesting developments that will affect the future of nanotechnology and nanomedicine.


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