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Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
Critical Reviews™ in Biomedical Engineering
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN Печать: 0278-940X
ISSN Онлайн: 1943-619X

Выпуски:
Том 47, 2019 Том 46, 2018 Том 45, 2017 Том 44, 2016 Том 43, 2015 Том 42, 2014 Том 41, 2013 Том 40, 2012 Том 39, 2011 Том 38, 2010 Том 37, 2009 Том 36, 2008 Том 35, 2007 Том 34, 2006 Том 33, 2005 Том 32, 2004 Том 31, 2003 Том 30, 2002 Том 29, 2001 Том 28, 2000 Том 27, 1999 Том 26, 1998 Том 25, 1997 Том 24, 1996 Том 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.2015014377
pages 161-181

Magnetic Resonance of Brown Adipose Tissue: A Review of Current Techniques

Houchun Harry Hu
Phoenix Children's Hospital

Краткое описание

This article reviews recent efforts in magnetic resonance imaging (MRI) and spectroscopy (MRS) of brown adipose tissues (BAT). The article does not differentiate classical BAT from more recently introduced beige/ brite adipocytes, as the unequivocal detection of these hybrid adipocytes with MRI and MRS remains an unmet need and unsolved challenge. BAT studies in both animals and humans have progressed rapidly during the past decade, spanning a broad spectrum of researchers from basic science laboratories to clinical investigators in primary care hospitals. While positron emission and computed tomography (PET/CT) is likely to remain as a reference modality in BAT imaging in the near future, approaches using MRI and MRS have emerged as viable alternatives. The specific signal contrasts that allow an MR system to assess BAT morphology and function are emphasized. Methods that measure tissue fat content, blood flow and perfusion, water diffusion, temperature, and substrate metabolism are explained and pertinent literature reports that utilize these approaches are highlighted. Finally, this article provides an outlook on research opportunities and future directions.


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