Выходит 6 номеров в год
ISSN Печать: 1045-4403
ISSN Онлайн: 2162-6502
Indexed in
Progesterone Receptor Isoform Functions in Normal Breast Development and Breast Cancer
Краткое описание
Progesterone acting through two isoforms of the progesterone receptor (PR), PRA and PRB, regulates proliferation and differentiation in the normal mammary gland in mouse, rat, and human. Progesterone and PR have also been implicated in the etiology and pathogenesis of human breast cancer. The focus of this review is recent advances in understanding the role of the PR isoformspecific functions in the normal breast and in breast cancer. Also discussed is information obtained from rodent studies and their relevance to our understanding of the role of progestins in breast cancer etiology.
-
Daniel Andrea R, Hagan Christy R, Lange Carol A, Progesterone receptor action: defining a role in breast cancer, Expert Review of Endocrinology & Metabolism, 6, 3, 2011. Crossref
-
Aupperlee Mark D, Leipprandt Jeffrey R, Bennett Jessica M, Schwartz Richard C, Haslam Sandra Z, Amphiregulin mediates progesterone-induced mammary ductal development during puberty, Breast Cancer Research, 15, 3, 2013. Crossref
-
Hiatt Robert A., Haslam Sandra Z., Osuch Janet, The Breast Cancer and the Environment Research Centers: Transdisciplinary Research on the Role of the Environment in Breast Cancer Etiology, Environmental Health Perspectives, 117, 12, 2009. Crossref
-
Goldhar Anita S., Duan Renqin, Ginsburg Erika, Vonderhaar Barbara K., Progesterone induces expression of the prolactin receptor gene through cooperative action of Sp1 and C/EBP, Molecular and Cellular Endocrinology, 335, 2, 2011. Crossref
-
Diep Caroline H, Daniel Andrea R, Mauro Laura J, Knutson Todd P, Lange Carol A, Progesterone action in breast, uterine, and ovarian cancers, Journal of Molecular Endocrinology, 54, 2, 2015. Crossref
-
Vandenberg Laura N., Nonmonotonic Responses in Endocrine Disruption, in Endocrine Disruption and Human Health, 2015. Crossref
-
Monostory Katalin, Pascussi Jean-Marc, Kóbori László, Dvorak Zdenek, Hormonal regulation of CYP1A expression, Drug Metabolism Reviews, 41, 4, 2009. Crossref
-
Rajkumar Lakshmanaswamy, Arumugam Arunkumar, Elsayed Ahmed, Schecter Scott, Kotkowski Eithan, Castillo Ruth, de la Torre Aleyah, Hernandez Cecilio, Long-term hormonal promotion overcomes genetic resistance to mammary cancer, Steroids, 76, 1-2, 2011. Crossref
-
Campo Verde Arboccó Fiorella, Sasso Corina V., Nasif Daniela L., Hapon María Belén, Jahn Graciela A., Effect of hypothyroidism on the expression of nuclear receptors and their co-regulators in mammary gland during lactation in the rat, Molecular and Cellular Endocrinology, 412, 2015. Crossref
-
McNally Sara, Martin Finian, Molecular regulators of pubertal mammary gland development, Annals of Medicine, 43, 3, 2011. Crossref
-
Peluso J.J., Liu X., Gawkowska A., Lodde V., Wu C.A., Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression, Molecular and Cellular Endocrinology, 320, 1-2, 2010. Crossref
-
Holley Aaron K., Kiningham Kelley K., Spitz Douglas R., Edwards Dean P., Jenkins Jeffrey T., Moore Michael R., Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells, The Journal of Steroid Biochemistry and Molecular Biology, 117, 1-3, 2009. Crossref
-
Camacho-Arroyo Ignacio, Hansberg-Pastor Valeria, Vázquez-Martínez Edgar Ricardo, Cerbón Marco, Mechanism of Progesterone Action in the Brain, in Hormones, Brain and Behavior, 2017. Crossref
-
Nacht A. Silvina, Beato Miguel, Vicent Guillermo P., Steroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation, Transcription, 8, 1, 2017. Crossref
-
Esber Nathalie, Cherbonnier Clément, Resche-Rigon Michèle, Hamze Abdallah, Alami Mouad, Fagart Jérôme, Loosfelt Hugues, Lombès Marc, Chabbert-Buffet Nathalie, Anti-Tumoral Effects of Anti-Progestins in a Patient-Derived Breast Cancer Xenograft Model, Hormones and Cancer, 7, 2, 2016. Crossref
-
Kim Tae Hoon, Jeong Jae-Wook, Uterus-Hormonal Regulation, in Encyclopedia of Reproduction, 2018. Crossref
-
Campo Verde Arboccó Fiorella, Persia Fabio Andres, Hapon María Belén, Jahn Graciela A., Hypothyroidism decreases JAK/STAT signaling pathway in lactating rat mammary gland, Molecular and Cellular Endocrinology, 450, 2017. Crossref
-
Guil-Luna S., Stenvang J., Brünner N., Sánchez-Céspedes R., Millán Y., Gómez-Laguna J., Mulas J. Martín de las, Progesterone Receptor Isoform Analysis by Quantitative Real-Time Polymerase Chain Reaction in Formalin-Fixed, Paraffin-Embedded Canine Mammary Dysplasias and Tumors, Veterinary Pathology, 51, 5, 2014. Crossref
-
Chaudhary Sanjib, Panda Aditya K., Mishra Dipti Ranjan, Mishra Sandip K., Toland Amanda Ewart, Association of +331G/A PgR Polymorphism with Susceptibility to Female Reproductive Cancer: Evidence from a Meta-Analysis, PLoS ONE, 8, 1, 2013. Crossref
-
Timmermans-Sprang Elpetra P. M., Gracanin Ana, Mol Jan A., Molecular Signaling of Progesterone, Growth Hormone, Wnt, and HER in Mammary Glands of Dogs, Rodents, and Humans: New Treatment Target Identification, Frontiers in Veterinary Science, 4, 2017. Crossref
-
Alvarado Antonieta, Lopes Ana C., Faustino-Rocha Ana I., Cabrita António M.S., Ferreira Rita, Oliveira Paula A., Colaço Bruno, Prognostic factors in MNU and DMBA-induced mammary tumors in female rats, Pathology - Research and Practice, 213, 5, 2017. Crossref
-
Kolla SriDurgaDevi, Morcos Mary, Martin Brian, Vandenberg Laura N., Low dose bisphenol S or ethinyl estradiol exposures during the perinatal period alter female mouse mammary gland development, Reproductive Toxicology, 78, 2018. Crossref
-
Aupperlee Mark D., Kariagina Anastasia, Zaremba Nicole, Basson Marc D., Schwartz Richard C., Haslam Sandra Z., The Proliferative Response to p27 Down-Regulation in Estrogen Plus Progestin Hormonal Therapy is Lost in Breast Tumors, Translational Oncology, 11, 2, 2018. Crossref
-
Sahores Ana, Figueroa Virginia, May María, Liguori Marcos, Rubstein Adrián, Fuentes Cynthia, Jacobsen Britta M., Elía Andrés, Rojas Paola, Sequeira Gonzalo R., Álvarez Michelle M., González Pedro, Gass Hugo, Hewitt Stephen, Molinolo Alfredo, Lanari Claudia, Lamb Caroline A., Increased High Molecular Weight FGF2 in Endocrine-Resistant Breast Cancer, Hormones and Cancer, 9, 5, 2018. Crossref
-
LaPlante Charlotte D, Bansal Ruby, Dunphy Karen A, Jerry D Joseph, Vandenberg Laura N, Oxybenzone Alters Mammary Gland Morphology in Mice Exposed During Pregnancy and Lactation, Journal of the Endocrine Society, 2, 8, 2018. Crossref
-
Dodda Balasunder R., Bondi Corry D., Hasan Mahmud, Clafshenkel William P., Gallagher Katie M., Kotlarczyk Mary P., Sethi Shalini, Buszko Ethan, Latimer Jean J., Cline J. Mark, Witt-Enderby Paula A., Davis Vicki L., Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer, Frontiers in Oncology, 9, 2019. Crossref
-
Pandit Ashish, Khare Lalit, Devarajan Padma V., Jain Ratnesh, Dandekar Prajakta, Breast Cancer Receptors and Targeting Strategies, in Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis, 39, 2019. Crossref
-
Lamb Caroline A, Fabris Victoria T, Jacobsen Britta M, Molinolo Alfredo, Lanari Claudia, Biological and clinical impact of imbalanced progesterone receptor isoform ratios in breast cancer, Endocrine-Related Cancer, 25, 12, 2018. Crossref
-
Lindet Clothilde, Révillion Françoise, Lhotellier Valérie, Hornez Louis, Peyrat Jean-Philippe, Bonneterre Jacques, Relationships between progesterone receptor isoforms and the HER/ErbB receptors and ligands network in 299 primary breast cancers, The International Journal of Biological Markers, 27, 2, 2012. Crossref
-
Recouvreux María Sol, Diaz Bessone María Inés, Taruselli Agustina, Todaro Laura, Lago Huvelle María Amparo, Sampayo Rocío G., Bissell Mina J., Simian Marina, Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population, Cells, 9, 9, 2020. Crossref
-
Albalawi Ibrahim A., Mir Rashid, Abu-Duhier Fasel M., Molecular Evaluation of PROGINS Mutation in Progesterone Receptor Gene and Determination of its Frequency, Distribution Pattern and Association with Breast Cancer Susceptibility in Saudi Arabia, Endocrine, Metabolic & Immune Disorders - Drug Targets, 20, 5, 2020. Crossref
-
Pedroza Diego A., Subramani Ramadevi, Tiula Kira, Do Anthony, Rashiraj Navya, Galvez Adriana, Chatterjee Animesh, Bencomo Alejandra, Rivera Servando, Lakshmanaswamy Rajkumar, Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation, Laboratory Investigation, 101, 6, 2021. Crossref
-
de Freitas Thiago, Zapaterini Joyce R., Moreira Cristiane M., de Aquino Ariana M., Alonso-Costa Luiz G., Bidinotto Lucas T., Kass Laura, Flaws Jodi A., Scarano Wellerson R., Barbisan Luis F., Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring, Food and Chemical Toxicology, 156, 2021. Crossref
-
Filgo Adam J., Foley Julie F., Puvanesarajah Samantha, Borde Aditi R., Midkiff Bentley R., Reed Casey E., Chappell Vesna A., Alexander Lydia B., Borde Pretish R., Troester Melissa A., Bouknight Schantel A. Hayes, Fenton Suzanne E., Mammary Gland Evaluation in Juvenile Toxicity Studies, Toxicologic Pathology, 44, 7, 2016. Crossref
-
Giulianelli Sebastian, Lamb Caroline A., Lanari Claudia, Progesterone receptors in normal breast development and breast cancer, Essays in Biochemistry, 65, 6, 2021. Crossref
-
Barker Holly E, Smyth Gordon K, Wettenhall James, Ward Teresa A, Bath Mary L, Lindeman Geoffrey J, Visvader Jane E, Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland, BMC Developmental Biology, 8, 1, 2008. Crossref
-
Lamb Caroline A., Fabris Victoria T., Lanari Claudia, Progesterone and breast, Best Practice & Research Clinical Obstetrics & Gynaecology, 69, 2020. Crossref
-
Salem Kelley, Kumar Manoj, Yan Yongjun, Jeffery Justin J., Kloepping Kyle C., Michel Ciara J., Powers Ginny L., Mahajan Aparna M., Fowler Amy M., Sensitivity and Isoform Specificity of 18F-Fluorofuranylnorprogesterone for Measuring Progesterone Receptor Protein Response to Estradiol Challenge in Breast Cancer, Journal of Nuclear Medicine, 60, 2, 2019. Crossref
-
Bonneterre Jacques, Bosq Jacques, Jamme Philippe, Valent Alexander, Gilles Erard M., Zukiwski Alexander A., Fuqua Suzanne A.W., Lange Carol A., O'Shaughnessy Joyce, Tumour and cellular distribution of activated forms of PR in breast cancers: a novel immunohistochemical analysis of a large clinical cohort, ESMO Open, 1, 4, 2016. Crossref
-
Mohammed Ghada, Mousa Noha A., Talaat Iman M., Ibrahim Haya, Saber-Ayad Maha, Breast Cancer Risk with Progestin Subdermal Implants: A Challenge in Patients Counseling, Frontiers in Endocrinology, 12, 2021. Crossref
-
Valdivia Guillermo, Alonso-Diez Ángela, Pérez-Alenza Dolores, Peña Laura, From Conventional to Precision Therapy in Canine Mammary Cancer: A Comprehensive Review, Frontiers in Veterinary Science, 8, 2021. Crossref
-
Vandenberg Laura N., Low Dose Effects and Nonmonotonic Dose Responses for Endocrine Disruptors, in Endocrine Disruption and Human Health, 2022. Crossref
-
Yuan Hongyan, Upadhyay Geeta, Lu Jin, Kopelovich Levy, Glazer Robert I., The Chemopreventive Effect of Mifepristone on Mammary Tumorigenesis Is Associated with an Anti-invasive and Anti-inflammatory Gene Signature, Cancer Prevention Research, 5, 5, 2012. Crossref
-
Daraei Abdolreza, Izadi Pantea, Khorasani Ghasemali, Nafissi Nahid, Naghizadeh Mohammad Mehdi, Younosi Nasim, Meysamie Alipasha, Mansoori Yaser, Nariman‐Saleh‐Fam Ziba, Bastami Milad, Saadatian Zahra, Zendehbad Zahra, Tavakkoly‐Bazzaz Javad, Methylation of progesterone receptor isoform A promoter in normal breast tissue: An epigenetic link between early age at menarche and risk of breast cancer?, Journal of Cellular Biochemistry, 120, 8, 2019. Crossref
-
Grant Emma, Bucklain Fatma A., Ginn Lucy, Laity Peter, Ciani Barbara, Bryant Helen E., Trackman Philip C., Progesterone receptor expression contributes to gemcitabine resistance at higher ECM stiffness in breast cancer cell lines, PLOS ONE, 17, 5, 2022. Crossref
-
Yu Jesse, Mu Qingxin, Fung Millie, Xu Xiaolin, Zhu Linxi, Ho Rodney J.Y., Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic response, Pharmacology & Therapeutics, 236, 2022. Crossref
-
Velesiotis Christos, Kanellakis Marinos, Vynios Demitrios H., Steviol glycosides affect functional properties and macromolecular expression of breast cancer cells, IUBMB Life, 74, 10, 2022. Crossref