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ISSN Печать: 1045-4403
ISSN Онлайн: 2162-6502
Indexed in
The Estrogen Receptor Activity Cycle: Dependence on Multiple Protein-Protein Interactions
Краткое описание
The estrogen steroid hormone receptor (ER) is a member of a family of related hormone-inducible transcriptional regulators. The function of these receptors is dependent on multiple protein-protein interactions with other cellular polypeptides. These contacts regulate the four steps in the receptor "life cycle": synthesis and nuclear transport, priming/storage, activation, and recycling. Each of these steps is mediated by the formation of distinct protein complexes and results in a temporal and spatial regulation of ER activity. This review focuses on the cellular proteins that interact with the ER, and the role that these interactions are believed to play in the regulation of ER.
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Jayachandran G., Fallon A.M., Evidence for expression of EcR and USP components of the 20-hydroxyecdysone receptor by a mosquito cell line, Archives of Insect Biochemistry and Physiology, 43, 2, 2000. Crossref
-
Picariello Lucia, Tonelli Francesco, Brandi Maria Luisa, Selective oestrogen receptor modulators in desmoid tumours, Expert Opinion on Investigational Drugs, 13, 11, 2004. Crossref
-
Diel Patrick, Tissue-specific estrogenic response and molecular mechanisms, Toxicology Letters, 127, 1-3, 2002. Crossref
-
Diel P, Schmidt S, Vollmer G, In vivo test systems for the quantitative and qualitative analysis of the biological activity of phytoestrogens, Journal of Chromatography B, 777, 1-2, 2002. Crossref
-
Hokanson R., Fudge R., Chowdhary R., Busbee D., Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide glyphosate, Human & Experimental Toxicology, 26, 9, 2007. Crossref
-
Mankame T, Hokanson R, Fudge R, Chowdhary R, Busbee D, Alteration of gene expression in human cells treated with the agricultural chemical diazinon: possible interaction in fetal development, Human & Experimental Toxicology, 25, 5, 2006. Crossref
-
Mankame T, Hokanson R, Chowdhary R, Busbee D, Altered gene expression in human cells induced by the agricultural chemical Enable, Toxicology and Industrial Health, 20, 6-10, 2004. Crossref
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Hokanson R, Hanneman W, Hennessey M, Donnelly K C, McDonald T, Chowdhary R, Busbee D L, DEHP, bis(2)-ethylhexyl phthalate, alters gene expression in human cells: possible correlation with initiation of fetal developmental abnormalities, Human & Experimental Toxicology, 25, 12, 2006. Crossref
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Hokanson Regina, Miller Susan, Hennessey Maxine, Flesher Mark, Hanneman William, Busbee David, Disruption of estrogen-regulated gene expression by dioxin: downregulation of a gene associated with the onset of non-insulin-dependent diabetes mellitus (type 2 diabetes), Human & Experimental Toxicology, 23, 12, 2004. Crossref
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Mankame T, Hokanson R, Fudge R, Chowdhary R, Busbee D, Altered gene expression in human cells treated with the insecticide diazinon: correlation with decreased DNA excision repair capacity, Human & Experimental Toxicology, 25, 2, 2006. Crossref
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Kampa Marilena, Pelekanou Vassiliki, Notas George, Stathopoulos Efstathios N., Castanas Elias, The estrogen receptor: two or more molecules, multiple variants, diverse localizations, signaling and functions. Are we undergoing a paradigm-shift as regards their significance in breast cancer?, Hormones, 12, 1, 2013. Crossref
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Cao Jingsong, Wood Marcie, Liu Yong, Hoffman Tim, Hyde Jim, Park-Sarge Ok-Kyong, Vore Mary, Estradiol Represses Prolactin-Induced Expression of Na+/Taurocholate Cotransporting Polypeptide in Liver Cells through Estrogen Receptor-α and Signal Transducers and Activators of Transcription 5a, Endocrinology, 145, 4, 2004. Crossref
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Hidalgo‐Lanussa Oscar, Baez‐Jurado Eliana, Echeverria Valentina, Ashraf Ghulam Md, Sahebkar Amirhossein, Garcia‐Segura Luis Miguel, Melcangi Roberto C., Barreto George E., Lipotoxicity, neuroinflammation, glial cells and oestrogenic compounds, Journal of Neuroendocrinology, 32, 1, 2020. Crossref
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Berthoud Hans-Rudolf, Synergy: A Concept in Search of a Definition, Endocrinology, 154, 11, 2013. Crossref