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Critical Reviews™ in Eukaryotic Gene Expression

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ISSN Печать: 1045-4403

ISSN Онлайн: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Nuclear Structure, Gene Expression and Development

Том 9, Выпуск 3-4, 1999, pp. 203-212
DOI: 10.1615/CritRevEukarGeneExpr.v9.i3-4.50
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Краткое описание

This article considers the extent to which features of nuclear structure are involved in the regulation of genome function. The recent renaissance in imaging technology has inspired a new determination to assign specific functions to nuclear domains or structures, many of which have been described as "factories" to express the idea that they coordinate nuclear processes in an efficient way. Visual data have been combined with genetic and biochemical information to support the idea that nuclear organization has functional significance. Particular DNA sequences or chromatin structures may nucleate domains that are permissive or restrictive of transcription, to which active or inactive loci could be recruited. Associations within the nucleus, as well as many nuclear structures, are transient and change dynamically during cell cycle progression and development. Despite this complexity, elucidation of the possible structural basis of epigenetic phenomena, such as the inheritance of a "cellular memory" of gene expression status, is an important goal for cell biology.
Topics for discussion include the regulatory effect of chromatin structure on gene expression, putative "nuclear addresses" for genes and proteins, the functional significance of nuclear bodies, and the role of the nuclear matrix in nuclear compartmentalization.

Ключевые слова: nucleus, transcription, chromatin.
ЦИТИРОВАНО В
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  7. Wang Yang, Newton Derek C., Miller Tricia L., Teichert Anouk-Martine, Phillips M. James, Davidoff Michail S., Marsden Philip A., An Alternative Promoter of the Human Neuronal Nitric Oxide Synthase Gene Is Expressed Specifically in Leydig Cells, The American Journal of Pathology, 160, 1, 2002. Crossref

  8. Maxwell Christopher A, Hendzel Michael J, The integration of tissue structure and nuclear function, Biochemistry and Cell Biology, 79, 3, 2001. Crossref

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  10. White P., Burton K A., Fowden A. L., Dauncey M. J., Developmental expression analysis of thyroid hormone receptor isoforms reveals new insights into their essential functions in cardiac and skeletal muscles, The FASEB Journal, 15, 8, 2001. Crossref

  11. Arnett-Mansfield Rebecca L., Graham J. Dinny, Hanson Adrienne R., Mote Patricia A., Gompel Anne, Scurr Lyndee L., Gava Natalie, de Fazio Anna, Clarke Christine L., Focal Subnuclear Distribution of Progesterone Receptor Is Ligand Dependent and Associated with Transcriptional Activity, Molecular Endocrinology, 21, 1, 2007. Crossref

  12. Schaufele Fred, Chang Ching-yi, Liu Weiqun, Baxter John D., Nordeen Steven K., Wan Yihong, Day Richard N., McDonnell Donald P., Temporally Distinct and Ligand-Specific Recruitment of Nuclear Receptor-Interacting Peptides and Cofactors to Subnuclear Domains Containing the Estrogen Receptor, Molecular Endocrinology, 14, 12, 2000. Crossref

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