Доступ предоставлен для: Guest
International Journal of Physiology and Pathophysiology
Главный редактор: Vadim F. Sagach (open in a new tab)

Выходит 4 номеров в год

ISSN Печать: 2155-014X

ISSN Онлайн: 2155-0158

SJR: 0.116

Association of Allelic Gene Polymorphisms of Matrix Gla-Protein System with Ischemic Atherothrombotic Stroke

Том 7, Выпуск 1, 2016, pp. 19-29
DOI: 10.1615/IntJPhysPathophys.v7.i1.30
Get accessGet access

Краткое описание

We examined 10 polymorphisms of matrix Gla-protein system (gene MGP − T-138 → C (rs1800802), G-7 → A (rs1800801), Thr83 → Ala (rs4236), gene VDR − FokI (rs2228570), BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), gene GGCX − Arg325 → Gln (rs699664), gene VKORC1 − T2255 → C (rs2359612), gene BMP-2 − Ser37 → Ala (rs2273073) in 170 patients with atherothrombotic ischemic stroke (IATS) and 124 healthy subjects (control group). It has been revealed that IATS is associated with polymorphic variants of genes MGP (G-7 → A) and VKORC1 (T2255 → C). The risk of IATS in the carriers of minor allele A/A (G-7 → A polymorphism) is 2.6 times higher than that in the carriers of the major allele (G/A + G/G), and C/C genotype (T2255 → C polymorphism) is 2.2 times higher compared to the homozygotes of a major allele. The coincidence of T/C and G/G, C/C and G/A genotypes in patients, as well as A/A genotype (G-7 → A polymorphism) with any genotype of T2255 → C polymorphism increases the risk of IATS.

ЦИТИРОВАНО В
  1. Abouzid Mohamed, Kruszyna Marlena, Burchardt Paweł, Kruszyna Łukasz, Główka Franciszek K., Karaźniewicz-Łada Marta, Vitamin D Receptor Gene Polymorphism and Vitamin D Status in Population of Patients with Cardiovascular Disease—A Preliminary Study, Nutrients, 13, 9, 2021. Crossref

660 Просмотры статей 7 Загрузка статей Метрики
660 ПРОСМОТРЫ 7 ЗАГРУЗКИ 1 Crossref ЦИТАТЫ Google
Scholar
ЦИТАТЫ

Статьи с похожим содержанием:

Analysis of Association between 11 Single-Nucleotide Polymorphisms and Endothelium-Dependent Vasodilation in Children with Type 1 Diabetes Mellitus International Journal of Physiology and Pathophysiology, Vol.8, 2017, issue 1
Olexiy O. Moibenko, Veronika L. Gurianova, Viktor E. Dosenko, V. G. Maidannik, Mykola V. Khaitovych, Nataliya B. Pranik, Sergii V. Goncharov
The Frequency of Allelic Polymorphism of Matrix Gla-Protein Gene in Patients with Acute Coronary Syndrome International Journal of Physiology and Pathophysiology, Vol.3, 2012, issue 2
Victoria Yu. Garbuzova, Veronika L. Gurianova, Viktor E. Dosenko, Oleksandr V. Ataman, Alexandr N. Parkhomenko
Matrix Gla-Protein Gene Polymorphism in Patients with Ischemic Atherothrombotic Stroke International Journal of Physiology and Pathophysiology, Vol.4, 2013, issue 2
Victoria Yu. Garbuzova, Olga I. Matlay, Yevheniy I. Dubovyk, Olga A. Obukhova, Anastasia O. Borodenko, Juriy A. Ataman, Oleksandr V. Ataman
Association between Methionine Synthase Reductase A66G Polymorphism and Male Infertility: A Meta-Analysis Critical Reviews™ in Eukaryotic Gene Expression, Vol.27, 2017, issue 1
Fan Jin, Xiangli Wu, Lin Zhang, Weihai Xu
Association Between CD14 Gene Polymorphism and Periodontitis: A Meta-Analysis Critical Reviews™ in Eukaryotic Gene Expression, Vol.23, 2013, issue 2
Yan Wen, Xiong Guo, Jingjing Zheng, Cuiyan Wu, Ling Gao, Tiezhou Hou, Pan Wang

Последний выпуск

Systemic Toxic Dental Sealant-Induced Effect on Nervous Tissue in vitro O. A. Znachkova, Irina V. Lushnikova, Galina G. Skibo, M. Y. Antonenko, Nana V. Voitenko Impact of Various Polyphenols on Disturbance of Cholesterol Metabolism under Insulin Resistance V. P. Fylymonenko, A. L. Zagayko Target Correction of Mitochondrial Dysfunction in Parkinson's Disease by Capicor Iryna M. Mankovska, Kateryna V. Rosova, Olga O. Gonchar, Valentina I. Nosar, Larisa. V. Bratus, Tetyana I. Drevitska, Ivan D. Glazyrin, Nina V. Karasevich, Iryna M. Karaban Changes in Ongoing Activity and Electrophysiological Characteristics of the Rat Retinal Ganglion Cells in Diabetes Mellitus N. Ya. Martyniuk, V. Yu. Maslov, Helen E. Purnyn, Svetlana A. Fedulova, Nikolai S. Veselovsky Sex Characteristics of Hydrogen Sulfide Effect on Ischemia-Reperfusion in Rat Myocardium Andrii V. Melnyk, Nataliia V. Zaichko, Oleksii A. Khodakovskyi, Olga V. Khodakivska Cardiohemodynamic Changes in Focal Cerebral Ischemia Roman R. Sharipov, Nataliya A. Dorofeyeva, Vadim F. Sagach Cerebral Hemodynamics and Electroencephalographic Pattern in Patients with Symptomatic Epilepsy at Combined Treatment with Transcranial Direct Current Stimulation Kateryna V. Yatsenko Physiological Endurance of Skeletal Muscle Increases under C60 Fullerene Application before Physical Load Tetyana Yu. Matvienko, Danylo Zavodovskiy, Iryna V. Mishchenko, Kateryna I. Bogutska, Yuriy I. Prylutskyy, Sofia Paradizova, Larisa Bezuh, Uwe Ritter, Peter Scharff Possible Mechanisms Underlying Association between Thyroiditis and Thyroid Papillary Carcinoma Tamara M. Myshunina, Mykola D. Tronko Index, Volume 9, 2018
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции Цены и условия подписки Begell House Контакты Language English 中文 Русский Português German French Spain