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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

Выходит 12 номеров в год

ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antitumor Effect of Combination Therapy of Proflamin with Cryosurgery of Meth-A Fibrosarcoma in BALB/c Mice

Том 7, Выпуск 4, 2005, pp. 539-546
DOI: 10.1615/IntJMedMushr.v7.i4.30
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Краткое описание

Proflamin (PRF), an antitumor agent, is orally effective against the syngeneic tumors in mice and is a new biological response modifier, which was isolated from the culture mycelium of Flammulina velutipes (W. Curt.: Fr.) Singer. Cryosurgery was used against tumors in this study in which cryoimmune effects were revealed. In this study, immunomodulation with PRF administration was evaluated in combination with cryosurgery. Cryosurgery was carried out on Meth-A fibrosarcoma 7 days after the inoculation of tumor cells into BALB/c mice. The tumor-bearing mice were found to have acquired tumor immunocompetence against the Meth-A tumors after receiving cryosurgery. This tumor immunocompetence reached nadir 2 weeks after the cryosurgery and increased gradually thereafter, reaching its maximum level at 5 weeks and remaining there for 7 weeks. Therapy in combination with cryosurgery and the immunopotentiator PRF was found to abolish the depression of tumor immunocompetence 2 weeks after cryosurgery. PRF was found to augment tumor immunity caused after cryosurgery, and thus it is coincident with modulation. The combination of cryosurgery and an immunopotentiator is suggested to be effective for maintaining the immunocompetence at a high level for a long duration and may be a useful tool in treating cancer.

ЦИТИРОВАНО В
  1. Zervakis Georgios I., Koutrotsios Georgios, Solid-State Fermentation of Plant Residues and Agro-industrial Wastes for the Production of Medicinal Mushrooms, in Medicinal Plants and Fungi: Recent Advances in Research and Development, 4, 2017. Crossref

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