Выходит 12 номеров в год
ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344
Indexed in
A Study on the Antioxidant Properties and Stability of Ergothioneine from Culinary-Medicinal Mushrooms
Краткое описание
The naturally occurring amino acid ergothioneine (EGT) has excellent free radical scavenging ability, which was not different to ascorbic acid. The IC50 values for EGT scavenging hydrogen peroxide, hydroxyl radicals, and superoxide anions were 11.65 ± 0.31, 70.31 ± 1.59, and 160.44 ± 0.32 μg/mL, respectively. The EGT concentration in different species of mushrooms was significantly different (p < 0.05), but it was not significantly related to the ability of the mushrooms to scavenge reactive oxygen species (p > 0.05). After isolating EGT from mushrooms, we demonstrated that the antioxidant ability of EGT accounts for about 25% of the total antioxidant ability of the extract. We studied the stability of EGT and found that it has excellent light, thermal, and acid-base stability. However, the presence of Cu2+ decreased the concentration of EGT. Unlike EGT, the thermal stability of the EGT extracted from Pleurotus citrinopileatus (PEGT) was not as good as EGT, while long-term high-temperature heating caused a decrease in the concentration of PEGT. The results of our study provide a basis for further investigating EGT from mushrooms for research and development.
-
Tanret C. Sur une base nouvelle retiree du seigle ergote, l-ergothioneine. C R Acad Sci. 1909;149:222-24.
-
Forster R, Spezia F, Papineau D, Sabadie C, Erdelmeier I, Moutet M, Yadan JC. Reproductive safety evaluation of L-ergothioneine. Food Chem Toxicol. 2015;80:85-91.
-
Halliwell B, Cheah IK, Drum CL. Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis. Biochem Biophys Res Commun. 2016;470(2):245-50.
-
Lee WY, Park EJ, Ahn JK. Supplementation of methionine enhanced the ergothioneine accumulation in the Ganoderma neo-japonicum mycelia. Appl Biochem Biotechnol. 2009;158(1):213-21.
-
Wasser SP. Medicinal mushroom science: history, current status, future trends, and unsolved problems. Int J Med Mushrooms. 2010;12(1):1-16.
-
Chang ST, Wasser SP. The role of culinary-medicinal mushrooms on human welfare with pyramid model for human health. Int J Med Mushrooms. 2012;14(2):95-134.
-
Wang Y, Li YH, Mo YL, Hu JJ, Zhang YX, Wang J. Analysis of antioxidant activity of ergothioneine from king oyster mushroom and the effect of environment on its stability. Food Ferm Ind. 2019;45(14):47-56. https://doi.org/10.13995/). cnki.11-1802/ts.020070.
-
Zhu BZ, Mao L, Fan RM, Zhu JG. Mechanism of protection by natural antioxidant ergothioneine against copper-induced oxidative damage to DNA and protein. Chin Sci Bull. 2011;56(27):2283-2288.
-
Akanmu D, Cecchini R, Aruoma IO, Halliwell B. The antioxidant action of ergothioneine. Arch Biochem Biophys. 1991; 288(1):10-16.
-
Herget T, Cotton M, Obert S, Klebl B. Therapeutic targets for treatment of HCV infections, methods of treating HCV infections of compounds useful thereof. US Patent US7341717-B2[P]. 2008 Nov 3.
-
Cohen N, Cohen J, Asatiani MD, Varshey VK, Yu H-T, Yang Y-C, Li Y-H, Mau J-L, Wasser SP. Chemical composition and nutritional and medicinal value of fruit bodies and submerged cultured mycelia of culinary-medicinal higher Basidiomycetes mushrooms. Int J Med Mushrooms. 2014;16(3):273-91.
-
Lin S-Y, Chen Y-K, Yu H-T, Barseghyan SG, Asatiani MD, Wasser SP, Mau J-L. Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms. Int J Med Mushrooms. 2013;15(3):315-23.
-
Chen SY, Ho KJ, Hsieh YJ, Wang LT, Mau JL. Contents of lovastatin, y-aminobutyric acid and ergothioneine in mushroom fruiting bodies and mycelia. Cienc Tecnol Aliment. 2012;47(2):274-278.
-
Zhu YF. Stability of reduced glutathione under different conditions. Mod Food Sci Technol. 2011;27(8):919-23.
-
Kim S, Lee TG. Stabilization of l-ascorbic acid in cosmetic emulsions. J Ind Eng Chem. 2018;57:193-98.
-
Chih HL, Kung JH, Ling YH, Ching HT, Shin YL, Mau J-L. Antioxidant properties of fruiting bodies, mycelia, and fermented products of the culinary-medicinal king oyster mushroom, Pleurotus eryngii (higher Basidiomycetes), with high ergothioneine content. Int J Med Mushrooms. 2013;15:267-76.
-
Yen MT, Chang YH, Huang SJ, Cheng MC, Mau JL. Extraction of ergothioneine from Pleurotus eryngii and P. citrinopileatus (Agaricomycetes) and preparation of its product. Int J Med Mushrooms. 2018:20(4):381-92.
-
Hu TX, Chen JW, Xu JY, Lu JY. Effects of coriolus and polysaccharide of gannoderm a on scavenging active oxygen species. Acta Biochim Biophys Sin. 1992;24:465-70.
-
Fu H, Xie B, Fan G, Ma S, Zhu X, Pan S. Effect of esterification with fatty acid of P-cryptoxanthin on its thermal stability and antioxidant activity by chemiluminescence method. Food Chem. 2010;122(3):602-9.
-
Lan MB, Zhang YH, Zheng Y, Yuan HH, Zhao HL, Gao F. Antioxidant and immunomodulatory activities of polysaccharides from moxa (Artemisia argyi) leaf. Food Sci Biotechnol. 2010;19(6):1463-69.
-
Chen SY, Ho KJ, Liang CH, Tsai CH, Huang LY, Mau JL. Preparation of culinary-medicinal king oyster mushroom Pleurotus eryngii-fermented products with high ergothioneine content and their taste quality. Int J Med Mushrooms. 2012;14:85-93.
-
Dubost NJ, Beelman RB, Peterson D, Daniel J, Royse DJ. Identification and quantification of ergothioneine in cultivated mushrooms by liquid chromatography-mass spectroscopy. Int J Med Mushrooms. 2006;8(3):215-22.
-
Kalaras MD, Richie JP, Calcagnotto A, Beelman RB. Mushrooms: a rich source of the antioxidants ergothioneine and glutathione. Food Chem. 2017;233:429-33.
-
Huang SJ, Lin CP, Tsai SY. Vitamin D2 content and antioxidant properties of fruit body and mycelia of edible mushrooms by UV-B irradiation. J Food Compos Anal. 2015;42:38-45.
-
Grundemann D. The ergothioneine transporter controls and indicates ergothioneine activity-a review. Prev Med. 2012;54:S71-S74.
-
Cheah Irwin K., Halliwell Barry, Could Ergothioneine Aid in the Treatment of Coronavirus Patients?, Antioxidants, 9, 7, 2020. Crossref
-
Niego Allen Grace, Rapior Sylvie, Thongklang Naritsada, Raspé Olivier, Jaidee Wuttichai, Lumyong Saisamorn, Hyde Kevin D., Macrofungi as a Nutraceutical Source: Promising Bioactive Compounds and Market Value, Journal of Fungi, 7, 5, 2021. Crossref
-
Tao Ye, Xiao Shan, Cai Jiaming, Wang Jihui, Li Lin, Effects of ergothioneine-enriched mushroom extract on oxidative stability, volatile compounds and sensory quality of emulsified sausage, Animal Bioscience, 34, 10, 2021. Crossref
-
Han Yiwen, Tang Xiuyang, Zhang Yuting, Hu Xuechao, Ren Lu-Jing, The current status of biotechnological production and the application of a novel antioxidant ergothioneine, Critical Reviews in Biotechnology, 41, 4, 2021. Crossref
-
Kitsanayanyong Lalitphan, Ohshima Toshiaki, Ergothioneine: a potential antioxidative and antimelanosis agent for food quality preservation, FEBS Letters, 596, 10, 2022. Crossref
-
Kido Shuhei, Chosa Etsuo, Tanaka Ryusuke, The effect of six dried and UV-C-irradiated mushrooms powder on lipid oxidation and vitamin D contents of fish meat, Food Chemistry, 398, 2023. Crossref
-
Liu Li, Sun Lei, Fan Sufang, Ma Junmei, Wang Yi, Li Qiang, Song Zhengyang, Sun Yong, Zhang Yan, Ponnayyan Sulochana Suresh, Determination of L-Ergothioneine in Cosmetics Based on Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry, International Journal of Analytical Chemistry, 2022, 2022. Crossref