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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

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ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Three Types of Geranylgeranyl Diphosphate Synthases from the Medicinal Caterpillar Fungus, Cordyceps militaris (Ascomycetes)

Том 16, Выпуск 2, 2014, pp. 115-124
DOI: 10.1615/IntJMedMushr.v16.i2.20
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Краткое описание

Geranylgeranyl diphosphate synthase (GGPPS) is a key enzyme in the carotenoid biosynthetic pathway, catalyzing the synthesis of its C20 precursor. In the present study, three types of ggpps genes were cloned and analyzed from the Caterpillar Medicinal Fungus Cordyceps militaris, a valued carotenoid-producing species. The sequences were named as ggpps727, ggpps191, and ggpps595. The open reading frame codes for predicted polypeptides of 464, 550, and 431 aa. Three predicted GGPPSs had a high similarity to that from Beauveria bassiana ARSEF 2860 with identity of 73%, 71%, and 56%, respectively. Homology comparison of the deduced peptide sequences of the various GGPPSs revealed highly conserved domains. Both GGPPS727 and GGPPS191 from C. militaris contained all five domains highly conserved among prenyltransferases as well as two aspartate-rich DDXX(XX)D motifs in domains II and V, which have been proven essential for prenyltransferase activity. By constructing the phylogenetic tree of fungal GGPPSs, it was found that fungi-derived GGPPSs could be divided into three clusters, suggesting there were three types of GGPPSs in fungi. Each type may be responsible for a different metabolism. Three types of GGPPSs from C. militaris belonged to the different clusters separately. Expression analysis of three ggpps genes during the fruit body cultivation of C. militaris by real-time polymerase chain reaction (PCR) suggested the ggpps 191 gene may be involved in the synthesis of carotenoids and ggpps 727 may be responsible for primary metabolism. This is the first report of the GGPPS from C. militaris, a valued edible and medicinal fungus.

ЦИТИРОВАНО В
  1. Yang Tao, Guo Mingmin, Yang Huaijun, Guo Suping, Dong Caihong, The blue-light receptor CmWC-1 mediates fruit body development and secondary metabolism in Cordyceps militaris, Applied Microbiology and Biotechnology, 100, 2, 2016. Crossref

  2. Jiang Keqing, Han Richou, Rhf1 gene is involved in the fruiting body production of Cordyceps militaris fungus, Journal of Industrial Microbiology and Biotechnology, 42, 8, 2015. Crossref

  3. Shang Changhua, Xu Xiaoli, Yuan Zhenhong, Wang Zhongming, Hu Lei, Alam Mohammad Asraful, Xie Jun, Cloning and differential expression analysis of geranylgeranyl diphosphate synthase gene from Dunaliella parva, Journal of Applied Phycology, 28, 4, 2016. Crossref

  4. Jiaojiao Zhang, Fen Wang, Kuanbo Liu, Qing Liu, Ying Yang, Caihong Dong, Heat and light stresses affect metabolite production in the fruit body of the medicinal mushroom Cordyceps militaris, Applied Microbiology and Biotechnology, 102, 10, 2018. Crossref

  5. Lou Hai-Wei, Zhao Yu, Tang Hong-Biao, Ye Zhi-Wei, Wei Tao, Lin Jun-Fang, Guo Li-Qiong, Transcriptome Analysis of Cordyceps militaris Reveals Genes Associated With Carotenoid Synthesis and Identification of the Function of the Cmtns Gene, Frontiers in Microbiology, 10, 2019. Crossref

  6. Lou Hai-Wei, Zhao Yu, Chen Bai-Xiong, Yu Ying-Hao, Tang Hong-Biao, Ye Zhi-Wei, Lin Jun-Fang, Guo Li-Qiong, Cmfhp Gene Mediates Fruiting Body Development and Carotenoid Production in Cordyceps militaris, Biomolecules, 10, 3, 2020. Crossref

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