Доступ предоставлен для: Guest
Портал Begell Электронная Бибилиотека e-Книги Журналы Справочники и Сборники статей Коллекции
International Journal of Medicinal Mushrooms
Импакт фактор: 1.211 5-летний Импакт фактор: 1.394 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344

Выпуски:
Том 21, 2019 Том 20, 2018 Том 19, 2017 Том 18, 2016 Том 17, 2015 Том 16, 2014 Том 15, 2013 Том 14, 2012 Том 13, 2011 Том 12, 2010 Том 11, 2009 Том 10, 2008 Том 9, 2007 Том 8, 2006 Том 7, 2005 Том 6, 2004 Том 5, 2003 Том 4, 2002 Том 3, 2001 Том 2, 2000 Том 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v18.i12.40
pages 1093-1104

Investigation of the Tiger Milk Medicinal Mushroom, Lignosus rhinocerotis (Agaricomycetes), as an Antiulcer Agent

Kar Lin Nyam
Department of Food Science with Nutrition, Faculty of Applied Sciences, UCSI University, Jalan Menara Gading, UCSI Heights (Taman Connaught), Cheras, Kuala Lumpur, Malaysia
Chia Yoong Chang
Department of Food Science with Nutrition, Faculty of Applied Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia
Chon Seng Tan
Ligno Biotech Sdn Bhd, Seri Kembangan, Selangor, Malaysia
Szu Ting Ng
Ligno Biotech Sdn Bhd, Seri Kembangan, Selangor, Malaysia

Краткое описание

The aim of this study was to determine the antiulcer activity of Lignosus rhinocerotis in rats. A total of 48 Sprague-Dawley rats were used in ethanol-induced, aspirin-induced, and water immersion-restraint stress-induced ulcer models. Rats were equally divided into 4 groups for each model and orally administered 5 mL/kg distilled water, 20 mg/kg omeprazole, as well as 250 and 500 mg/kg of L. rhinocerotis powder. L. rhinocerotis powder at both 250 and 500 mg/kg doses demonstrated significant (P < 0.05) protection against gastric ulceration in all the induced ulcer models. Histological studies revealed severe damage and hemorrhage of gastric mucosa in the negative control group for all ulcer-induced models. The study suggests that L. rhinocerotis powder possesses dose-dependent antiulcer activity in the gastric mucosa, as ascertained grossly and histologically, compared with the negative control groups.


Articles with similar content:

Thyroidal Effects of Di-(2-Ethylhexyl) Phthalate in Rats of Different Selenium Status
Journal of Environmental Pathology, Toxicology and Oncology, Vol.31, 2012, issue 2
Isabelle Hininger-Favier, Anne-Marie Roussel, Murat Kizilgun, Alain Favier, Belma Kocer, Filiz Hincal, Pinar Erkekoglu, Walid Rachidi
Nrf2/HO-1 Mediated Protective Activity of Genistein Against Doxorubicin-Induced Cardiac Toxicity
Journal of Environmental Pathology, Toxicology and Oncology, Vol.38, 2019, issue 2
Guangping Zhang, Yi Wu, Yukiat Lin, Miao Chen, Raghava Sriramaneni, Minyan Dang, Gopala Krishna Chinnaboina, Sushil Kumar Sah, Vijaya Paul Samuel
Amelioration of Doxorubicin-Induced Cardiac and Renal Toxicity by Oxycarotenoid Lutein and Its Mechanism of Action
Journal of Environmental Pathology, Toxicology and Oncology, Vol.35, 2016, issue 3
Thattaruparambil Raveendran Nithya, Ramadasan Kuttan, Edakkadath Raghavan Sindhu , Ponnamparambil Purushothaman Binitha
Trichosanthes dioica Fruit Extract Ameliorates Arsenic-Induced Brain Toxicity in Male Albino Rats
Journal of Environmental Pathology, Toxicology and Oncology, Vol.32, 2013, issue 2
Sanjib Bhattacharya, Pallab Kanti Haldar
Trichosanthes dioica Root Alleviates Arsenic Induced Myocardial Toxicity in Rats
Journal of Environmental Pathology, Toxicology and Oncology, Vol.32, 2013, issue 3
Sanjib Bhattacharya, Pallab Kanti Haldar