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International Journal of Medicinal Mushrooms
Главный редактор: Solomon P. Wasser (open in a new tab)

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ISSN Печать: 1521-9437

ISSN Онлайн: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antitumor Properties of Submerged Cultivated Biomass and Extracts of Medicinal Mushrooms of Genus Hypsizygus Singer (Agaricomycetideae)

Том 10, Выпуск 1, 2008, pp. 25-35
DOI: 10.1615/IntJMedMushr.v10.i1.40
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Краткое описание

The present article describes the development of media for high-yield cultivation of medicinal mushrooms Hypsizygus marmoreus and H. ulmarius and the results of in vivo investigations into the antitumor activity of the water extracts of the mycelia of both species and of the total polysaccharide fraction of H. ulmarius. The media were optimized using statistical experimental design methodologies, including full factorial design and steepest ascent. The mycelia yield of H. ulmarius amounted to 32-33 g/L of air-dried biomass on the 3rd to 4th day of cultivation. The corresponding figures for two strains of H. marmoreus, Hm-1 and Hm-2, were 26 and 17 g/L, respectively, on the 7th day of cultivation. The water content of air-dried biomass did not exceed 5%. The antitumor activity was studied in vivo on adult male hybrid mice (C57Bl/6 × DBA/2)F1 with transplantable tumor T-cell lymphoma P388. The inhibition ratio (IR) of tumor growth reached 80% for the water extract of H. ulmarius mycelium and 38% and 59%, respectively, for the two strains of H. marmoreus. The water-soluble polysaccharide fraction of H. ulmarius mycelium contained glucose, galactose, mannose, rhamnose, arabinose, and xylose in the relative amounts of 23.5, 9.5, 7, 2, 1.5, and 1, respectively; its antitumor activity was tested in 2 doses, 2 and 20 mg/kg/day. The 2 mg/ kg/day dose was more effective than either the 20 mg/kg/day dose or the mycelium water extract. The results prove H. ulmarius to be a promising source of antitumor polysaccharides.

ЦИТИРОВАНО В
  1. Qiu Chengshu, Yan Wenjuan, Deng Wangqiu, Song Bin, Li Taihui, Genetic Diversity Analysis ofHypsizygus marmoreuswith Target Region Amplification Polymorphism, The Scientific World Journal, 2014, 2014. Crossref

  2. Wu Ying-Ying, Shang Jun-Jun, Li Yan, Zhou Chen-Li, Hou Di, Li Jia-Li, Tan Qi, Bao Da-Peng, Yang Rui-Heng, The complete mitochondrial genome of the Basidiomycete edible fungus Hypsizygus marmoreus, Mitochondrial DNA Part B, 3, 2, 2018. Crossref

  3. Kuznetsova Iren, Zaitsev Boris, Krasnopolskaya Larissa, Teplykh Andrey, Semyonov Alexander, Avtonomova Anastasia, Ziangirova Mayya, Smirnov Andrey, Kolesov Vladimir, Influence of Humidity on the Acoustic Properties of Mushroom Mycelium Films Used as Sensitive Layers for Acoustic Humidity Sensors, Sensors, 20, 9, 2020. Crossref

  4. Öztürk Ceren, Atila Funda, Changes in lignocellulosic fractions of growing substrates during the cultivation of Hypsizygus ulmarius mushroom and its effects on mushroom productivity, Scientia Horticulturae, 288, 2021. Crossref

  5. Krasnopolskaya Larissa, Shuktueva Maria, Golyshkin Aleksandr, Almyasheva Nailya, Yarina Maria, Optimization of the Nutrient Medium for Flammulina velutipes Submerged Biomass Production and Micromorphology of Its Mycelium, Fermentation, 7, 3, 2021. Crossref

  6. Vetchinkina Elena, Fomin Alexander, Navolokin Nikita, Shirokov Alexander, Proteins and polysaccharides from vegetative mycelium of medicinal basidiomycete Lentinus edodes display cytotoxicity towards human and animal cancer cell lines, International Journal of Biological Macromolecules, 195, 2022. Crossref

  7. Wang Gang, Chen Lianfu, Tang Weiqi, Wang Yuanyuan, Zhang Qing, Wang Hongbo, Zhou Xuan, Wu Haofeng, Guo Lin, Dou Meijie, Liu Lei, Wang Baiyu, Lin Jingxian, Xie Baogui, Wang Zhengchao, Liu ZhongJian, Ming Ray, Zhang Jisen, Identifying a melanogenesis-related candidate gene by a high-quality genome assembly and population diversity analysis in Hypsizygus marmoreus, Journal of Genetics and Genomics, 48, 1, 2021. Crossref

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