Выходит 12 номеров в год
ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344
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Optimization of the Production of Extracellular Polysaccharide from the Shiitake Medicinal Mushroom Lentinus edodes (Agaricomycetes) Using Mutation and a Genetic Algorithm−Coupled Artificial Neural Network (GA-ANN)
Краткое описание
Exopolysaccharide (EPS) production by a strain of Lentinus edodes was studied via the effects of treatments with ultraviolet (UV) irradiation and acridine orange. Furthermore, optimization of EPS production was studied using a genetic algorithm coupled with an artificial neural network in submerged fermentation. Exposure to irradiation and acridine orange resulted in improved EPS production (2.783 and 5.548 g/L, respectively) when compared with the wild strain (1.044 g/L), whereas optimization led to improved productivity (23.21 g/L). The EPS produced by various strains also demonstrated good DPPH scavenging activities of 45.40−88.90%, and also inhibited the growth of Escherichia coli and Klebsiella pneumoniae. This study shows that multistep optimization schemes involving physical-chemical mutation and media optimization can be an attractive strategy for improving the yield of bioactives from medicinal mushrooms. To the best of our knowledge, this report presents the first reference of a multistep approach to optimizing EPS production in L. edodes.
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Adeoye Adekunle Olusegun, Lateef Agbaje, Biotechnological valorization of cashew apple juice for the production of citric acid by a local strain of Aspergillus niger LCFS 5, Journal of Genetic Engineering and Biotechnology, 19, 1, 2021. Crossref
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Lateef A., Darwesh O. M., Matter I. A., Microbial Nanobiotechnology: The Melting Pot of Microbiology, Microbial Technology and Nanotechnology, in Microbial Nanobiotechnology, 2021. Crossref
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Adeoye Adekunle Olusegun, Lateef Agbaje, Improving the Yield of Citric Acid Through Valorization of Cashew Apple Juice by Aspergillus niger: Mutation, Nanoparticles Supplementation and Taguchi Technique, Waste and Biomass Valorization, 13, 4, 2022. Crossref
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Xiang Quanju, Zhang Huijuan, Chen Xiaoqian, Hou Shiyao, Gu Yunfu, Yu Xiumei, Zhao Ke, Zhang Xiaoping, Ma Menggen, Chen Qiang, Petri Penttinen, Chen Xiaoqiong, Enhanced Effects of Iron on Mycelial Growth, Metabolism and In Vitro Antioxidant Activity of Polysaccharides from Lentinula edodes, Bioengineering, 9, 10, 2022. Crossref