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International Journal of Medicinal Mushrooms
Импакт фактор: 1.423 5-летний Импакт фактор: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Печать: 1521-9437
ISSN Онлайн: 1940-4344

Выпуски:
Том 21, 2019 Том 20, 2018 Том 19, 2017 Том 18, 2016 Том 17, 2015 Том 16, 2014 Том 15, 2013 Том 14, 2012 Том 13, 2011 Том 12, 2010 Том 11, 2009 Том 10, 2008 Том 9, 2007 Том 8, 2006 Том 7, 2005 Том 6, 2004 Том 5, 2003 Том 4, 2002 Том 3, 2001 Том 2, 2000 Том 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v1.i1.30
pages 31-62

Medicinal Properties of Substances Occurring in Higher Basidiomycetes Mushrooms: Current Perspectives (Review)

Solomon P. Wasser
N.G. Kholodny Institute of Botany, NAS of Ukraine, 2 Tereshchenkovskaya Str., Kiev 01004, Ukraine; International Center for Cryptogamic Plants and Fungi, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
Alexander L. Weis
international Myko Biologies, Inc., Texas Research Park, 14785 Omicron Dr., Suite 104, San Antonio, TX, 78245, U.S.A.

Краткое описание

This review highlights some of the recently isolated and identified substances of higher Basidiomycetes mushroom origin that express promising antitumor, immune modulating, cardiovascular and antihyper-cholesterolemia, antiviral, antibacterial, antiparasitic, hepatoprotective, and antidiabetic effects. Medicinal mushrooms have a long history of use in folk medicine. Mushrooms useful against cancers of the stomach, esophagus, lungs, etc., are known in China, Russia, Japan, and Korea, as well as the United States and Canada. There are approximately two hundred species of mushrooms that have been found to markedly inhibit the growth of different kinds of tumors. However, most of the mushroom origin antitumor substances have not been clearly defined. Several antitumor polysaccharides, such as hetero-β-glucans and their protein complexes (e.g., xyloglucans, and acidic β-glucan containing uronic acid), as well as dietary fibers, lectins, and terpenoids, have been isolated from medicinal mushrooms. In Japan, Russia, China, and the United States, several different polysaccharide antitumor agents have been developed from the fruiting body, mycelia, and culture medium of various medicinal mushrooms (Lentinus edodes, Ganoderma lucidum, Schizophyllum commune, Trametes versicolor, Inonotus obliquus, and Flammulina velutipes). Both cellular components and secondary metabolites of a large number of mushrooms have been shown to effect the immune system of the host and therefore could be used to treat a variety of disease states. The information presented in this review is helpful in exploring and understanding the rich traditions of medicinal mushrooms in Eastern and Western cultures and medicine.


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