RT Journal Article ID 1b2193ac61a4ee85 A1 Leon-Bollotte, L. A1 Lamrani, M. A1 Plenchette-Colas, S. A1 Jeannin, Jean-Francois A1 Bettaieb, Ali T1 Post-Translational Regulation of Fas/CD95 in Cell Death and Survival: Role of Nitric Oxide JF Onco Therapeutics JO OT YR 2010 FD 2010-07-01 VO 1 IS 4 SP 297 OP 305 K1 Fas/CD95 K1 phosphorylation K1 nitration K1 palmitoylation K1 glutathionylation AB Fas/CD95 or APO-1 is one of the best-characterized members of the tumor necrosis factor receptor (TNFR) superfamily. Triggering of Fas by its ligand (FasL) leads to receptor oligomerization and the formation of the death-induced signaling complex (DISC), and thereby activates the caspase cascade, which culminates in apoptotic cell death. Many post-translational modifications are recognized as critical modifications for the early events of Fas regulation and function. Here, we summarize the current knowledge on Fas post-translational modifications, including phosphorylation, nitration, palmitoylation, and glutathionylation. PB Begell House LK https://www.dl.begellhouse.com/journals/2c6306423483e001,5293dc0d3975e7ba,1b2193ac61a4ee85.html