RT Journal Article ID 30c0b5be70f8ebb7 A1 Valdes Cabrera, Diana A1 Garcia, Jesus Osvaldo Dominguez A1 Sarty, Gordon T1 Diffusion-Weighted Magnetic Resonance Imaging Attenuation Factors and Their Selection for Cancer Diagnosis and Monitoring JF Critical Reviews™ in Biomedical Engineering JO CRB YR 2015 FD 2016-03-10 VO 43 IS 2-3 SP 201 OP 212 K1 magnetic resonance imaging K1 diffusion-weighted imaging K1 oncology K1 b-values K1 staging AB Diffusion-weighted imaging (DWI) is based on the detection of water molecule movement in interstitial and intracellular space, and that motion may be restricted in ischemia and in tumors. An early diagnosis and characterization of several cancer related diseases is possible with DWI. Diffusion-weighted images are therefore important for patient management. Knowledge of the technical requirements for DWI, including a suitable selection of b-values for differentiating between perfusion and true diffusion, as well as an understanding of the advantages and limitations of different b-values selections, is necessary to obtain reliable diagnostic results. The aim of this article is to review the fundamentals of the DWI technique, the common protocols used, b-value selection, and DWI's main contribution to neoplasm detection and staging. PB Begell House LK https://www.dl.begellhouse.com/journals/4b27cbfc562e21b8,0c5c234e50d6b568,30c0b5be70f8ebb7.html