RT Journal Article ID 68e2ab091865a1fa A1 Morel, Sylvie A1 Arnould, Stéphanie A1 Vitou, Manon A1 Boudard, Frédéric A1 Guzman, Caroline A1 Poucheret, Patrick A1 Fons, Françoise A1 Rapior, Sylvie T1 Antiproliferative and Antioxidant Activities of Wild Boletales Mushrooms from France JF International Journal of Medicinal Mushrooms JO IJM YR 2018 FD 2018-03-06 VO 20 IS 1 SP 13 OP 29 K1 activity K1 antioxidant K1 antiproliferative K1 Boletales K1 Boletus K1 Caloboletus K1 colon adenocarcinoma K1 Gyroporus K1 HCT116 K1 medicinal mushrooms K1 Omphalotus K1 ORAC K1 phenolics K1 Rubroboletus K1 Suillus AB We selected edible and inedible mushrooms growing in the Mediterranean area of France to screen their biological activity: Caloboletus calopus, Rubroboletus lupinus, R. pulchrotinctus, R. satanas, Gyroporus castaneus, Suillus luteus, and Omphalotus olearius. Mushrooms were sequentially extracted using cyclohexane, chloroform, ethanol, and water. The antiproliferative activity against the HCT116 colon adenocarcinoma cell line and the antioxidant properties (DPPH radical scavenging assay, Folin-Ciocalteu assay, and oxygen radical absorbance capacity) of the Boletales extracts were evaluated and compared. Among the 28 mushroom extracts evaluated, 11 presented antiproliferative activity against HCT116 cells. These activities were not linked to antioxidant capacity. Among the antioxidant extracts, most were aqueous extracts in the oxygen radical absorbance capacity assay, whereas the highest values on the Folin-Ciocalteu and DPPH assays were noted for chloroform, ethanol, or aqueous extracts, depending on the mushroom species. Further studies are necessary to identify bioactive compounds and to valorize the mushrooms−for edible species, directly as health foods, or, for inedible mushrooms, as ingredients in the pharmaceutical and food industries. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,058bdb3d1a5aef61,68e2ab091865a1fa.html