RT Journal Article
ID 68e2ab091865a1fa
A1 Morel, Sylvie
A1 Arnould, Stéphanie
A1 Vitou, Manon
A1 Boudard, Frédéric
A1 Guzman, Caroline
A1 Poucheret, Patrick
A1 Fons, Françoise
A1 Rapior, Sylvie
T1 Antiproliferative and Antioxidant Activities of Wild Boletales Mushrooms from France
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2018
FD 2018-03-06
VO 20
IS 1
SP 13
OP 29
K1 activity
K1 antioxidant
K1 antiproliferative
K1 Boletales
K1 Boletus
K1 Caloboletus
K1 colon adenocarcinoma
K1 Gyroporus
K1 HCT116
K1 medicinal mushrooms
K1 Omphalotus
K1 ORAC
K1 phenolics
K1 Rubroboletus
K1 Suillus
AB We selected edible and inedible mushrooms growing in the Mediterranean area of France to screen their biological activity: Caloboletus calopus, Rubroboletus lupinus, R. pulchrotinctus, R. satanas, Gyroporus castaneus, Suillus luteus, and Omphalotus olearius. Mushrooms were sequentially extracted using cyclohexane, chloroform, ethanol, and water. The antiproliferative activity against the HCT116 colon adenocarcinoma cell line and the antioxidant properties (DPPH radical scavenging assay, Folin-Ciocalteu assay, and oxygen radical absorbance capacity) of the Boletales extracts were evaluated and compared. Among the 28 mushroom extracts evaluated, 11 presented antiproliferative activity against HCT116 cells. These activities were not linked to antioxidant capacity. Among the antioxidant extracts, most were aqueous extracts in the oxygen radical absorbance capacity assay, whereas the highest values on the Folin-Ciocalteu and DPPH assays were noted for chloroform, ethanol, or aqueous extracts, depending on the mushroom species. Further studies are necessary to identify bioactive compounds and to valorize the mushrooms−for edible species, directly as health foods, or, for inedible mushrooms, as ingredients in the pharmaceutical and food industries.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,058bdb3d1a5aef61,68e2ab091865a1fa.html