每年出版 4 期
ISSN 打印: 1050-6934
ISSN 在线: 1940-4379
Indexed in
Cost-Effectiveness and Economic Impact of the KineSpring® Knee Implant System in the Treatment of Knee Osteoarthritis in the United Kingdom
摘要
Background: Knee osteoarthritis (OA) is a condition affecting 8.5 million individuals in the United Kingdom (UK). Although many treatment options are available, there is a need for a less-invasive treatment for individuals with mild to moderate knee OA. The purpose of the present study was to determine whether the KineSpring System is a more effective treatment for knee OA when compared to other standard treatments, taking into consideration cost-utility ratios.
Methods: Data was collected for the UK population breakdown. A literature search provided data on conservative and surgical treatment costs and functional outcome scores. The KineSpring System outcome scores were obtained from two trials. Quality-adjusted life years (QALYs) gained and cost-utility ratios were calculated for each treatment option, assuming a lifetime durability as well as 10-year durability.
Results: Assuming lifetime durability, the cost-utility ratios of surgical treatment, total knee arthroplasty (TKA), the KineSpring System, and conservative treatments, compared to no treatment are £1,303±22/QALY, £821±175/QALY, £796±73/QALY and £11,096±1188/QALY, respectively. Assuming a treatment durability of 10 years, the cost-utility ratio of surgical treatment, TKA, the KineSpring System, and conservative treatments, compared to no treatment are £4,153±95 per QALY, £2,698±768 per QALY, £2,848±345 per QALY, and £10,624±1528 per QALY, respectively.
Conclusion: This study demonstrates that the KineSpring System is a cost-effective treatment for knee OA and is comparable to current standard-of-care treatments. Further research is needed to assess the long-term outcomes associated with the KineSpring System.
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Wolff Matthias, Haasper Carl, Zahar Akos, Gauck Christian, Gehrke Thorsten, Citak Mustafa, Severe metallosis and elevated chromium in serum following implantation of the joint unloading implant system, Archives of Orthopaedic and Trauma Surgery, 137, 12, 2017. Crossref
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Kamaraj Achi, To Kendrick, Seah KT Matthew, Khan Wasim S., Modelling the cost-effectiveness of total knee arthroplasty: A systematic review, Journal of Orthopaedics, 22, 2020. Crossref