图书馆订阅: Guest
免疫学评论综述™

每年出版 6 

ISSN 打印: 1040-8401

ISSN 在线: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Functions of IL-4 and Control of Its Expression

卷 17, 册 1, 1997, pp. 1-32
DOI: 10.1615/CritRevImmunol.v17.i1.10
Get accessGet access

摘要

IL-4 has been called the "prototypic immunoregulatory cytokine." Like many cytokines, it can affect a variety of target cells in multiple ways. IL-4 has an important role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It is produced only by a subset of activated hematopoietic cells, including T cells and FcεRl+ mast cells and basophils. Based on the different tissue distribution and access to distinct target cells, IL-4 derived from T and FcεRl+ cells may have quite different effects on these immunological processes. In view of this, as well as the clear correlation of aberrant expression with disease, it is of interest to understand the signals that regulate IL-4 expression in a cell-specific manner. Recently, progress has been made in defining the T-cell- and FcεRl-receptor-mediated signals that stimulate IL-4 gene expression. These studies have demonstrated that there are common and cell-specific signaling pathways that regulate production of this cytokine. In this review, we summarize the activities of IL-4 defined both in vitro and in vivo and compare the signals leading to IL-4 expression in cells of both T- and mast-cell lineage.

对本文的引用
  1. Mire-Sluis Anthony R., Interleukin-4, in Cytokines, 1998. Crossref

  2. Gonzales J. R., Gröger Sabine, Boedeker Rolf-Hasso, Meyle Jörg, Expression and secretion levels of Th1 and Th2 cytokines in patients with aggressive periodontitis, Clinical Oral Investigations, 16, 5, 2012. Crossref

  3. Cheng An-Sheng, Cheng Yu-Hsiang, Chang Tsu-Liang, Scopoletin attenuates allergy by inhibiting Th2 cytokines production in EL-4 T cells, Food & Function, 3, 8, 2012. Crossref

  4. Hulshof Sandra, Montagne Lisette, De Groot Corline J.A., Van Der Valk Paul, Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions, Glia, 38, 1, 2002. Crossref

  5. Moldoveanu Andrei I., Shephard Roy J., Shek Pang N., The Cytokine Response to Physical Activity and Training, Sports Medicine, 31, 2, 2001. Crossref

  6. Gao P.-S., Mao X.-Q., Hopkin J. M., Adra C. N., Yang X., Shirakawa T., Functional significance of polymorphisms of the interleukin-4 and interleukin-13 receptors in allergic disease, Clinical & Experimental Allergy, 30, 12, 2000. Crossref

  7. TANAKA Hiroyuki, Functional Molecules in Allergic Bronchial Asthma, YAKUGAKU ZASSHI, 122, 9, 2002. Crossref

  8. Smith Justine R, Hart Prue H, Williams Keryn A, Basic pathogenic mechanisms operating in experimental models of acute anterior uveitis, Immunology and Cell Biology, 76, 6, 1998. Crossref

  9. Massey H. Davis, McPherson Richard A., Mediators of Inflammation, in Henry's Clinical Diagnosis and Management by Laboratory Methods, 2011. Crossref

  10. Grandhi Sumalatha, Donnelly Louise E, Rogers Duncan F, Phytoceuticals: the new ‘physic garden’ for asthma and chronic obstructive pulmonary disease, Expert Review of Respiratory Medicine, 1, 2, 2007. Crossref

  11. Jun Tae-Youn, Lee Kyoung-Uk, Pae Chi-Un, Chae Jeong-Ho, Bahk Won-Myong, Kim Kwang-Soo, Han Hoon, Polymorphisms of interleukin-4 promoter and receptor gene for schizophrenia in the Korean population, Psychiatry and Clinical Neurosciences, 57, 3, 2003. Crossref

  12. Li-Weber Min, Giaisi Marco, Chlichlia Katerina, Khazaie Khashayarsha, Krammer Peter H., Human T cell leukemia virus type I Tax enhances IL-4 gene expression in T cells, European Journal of Immunology, 31, 9, 2001. Crossref

  13. Chow Louis W.C., Loo Wings T.Y., Sham Jonathan S.T., Cheung Mary N.B., Radix Bupleuri Containing Compound (KY88 Liver-Livo) Induces Apoptosis and Production of Interleukin-4 and Tumor Necrosis Factor-α in Liver Cancer Cellsin Vitro, The American Journal of Chinese Medicine, 32, 02, 2004. Crossref

  14. Shekari Mohammad, Kordi-Tamandani Dor Mohammad, MalekZadeh Kianoosh, Sobti Ranbir Chander, Karimi Samieh, Suri Vanita, Effect of Anti-inflammatory (IL-4, IL-10) Cytokine Genes in Relation to Risk of Cervical Carcinoma, American Journal of Clinical Oncology, 35, 6, 2012. Crossref

  15. Park Jin, Kim Seung H., Cho Daeho, Kim Tae S., Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity, Immunology, 116, 1, 2005. Crossref

  16. Uzonna Jude E., Bretscher Peter A., Anti-IL-4 antibody therapy causes regression of chronic lesions caused by medium-doseLeishmania major infection in BALB/c mice, European Journal of Immunology, 31, 11, 2001. Crossref

  17. Jeong Hyun-Ja, Chung Hwan-Suck, An Hyo-Jin, Seo Sang-Wan, Kim Tae-gyun, Won Jin-Hee, Shin Jo-Young, Ahn Kyoo-Seok, Kim Hyung-Min, The Immune-Enhancing Effect of the Herbal Combination Bouum-Myunyuk-Dan, Biological and Pharmaceutical Bulletin, 27, 1, 2004. Crossref

  18. Keen Judith C., Cianferoni Antonella, Florio Giovanni, Guo Jia, Chen Rongbing, Roman Jessica, Wills-Karp Marsha, Casolaro Vincenzo, Georas Steve N., Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells, Immunology, 117, 1, 2006. Crossref

  19. Bretscher Peter A, Hamilton Duane, Ogunremi Oladele, What information is needed to design effective vaccination against intracellular pathogens causing chronic disease?, Expert Review of Vaccines, 1, 2, 2002. Crossref

  20. Barry Claire E., Nolan Yvonne, Clarke Rachael M., Lynch Aileen, Lynch Marina A., Activation of c-Jun-N-terminal kinase is critical in mediating lipopolysaccharide-induced changes in the rat hippocampus, Journal of Neurochemistry, 93, 1, 2005. Crossref

  21. Bonney Elizabeth A., Maternal tolerance is not critically dependent on interleukin-4, Immunology, 103, 3, 2001. Crossref

  22. Böttcher M. F., Häggström P., Björkstén B., Jenmalm M. C., Total and allergen-specific immunoglobulin A levels in saliva in relation to the development of allergy in infants up to 2 years of age, Clinical & Experimental Allergy, 32, 9, 2002. Crossref

  23. Li-Weber Min, Giaisi Marco, Treiber Monika?K., Krammer Peter?H., The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T cells, European Journal of Immunology, 32, 12, 2002. Crossref

  24. Shen Siou-Ru, Hsu Wei-Hsuan, Lee Chia-Chen, Chang Wen-Chang, Wu She-Ching, Buckwheat extracts (Fagopyrum tataricum) and rutin attenuate Th2 cytokines production and cellular allergic effects in vitro and in vivo, Journal of Functional Foods, 4, 4, 2012. Crossref

  25. Sherman Melanie A., Secor Virginia H., Lee Susan K., Lopez Richard D., Brown Melissa A., STAT6-independent production of IL-4 by mast cells, European Journal of Immunology, 29, 4, 1999. Crossref

  26. Lin Yue-Zhi, Cao Xue-Zhi, Li Liang, Li Li, Jiang Cheng-Gang, Wang Xue-Feng, Ma Jian, Zhou Jian-Hua, The pathogenic and vaccine strains of equine infectious anemia virus differentially induce cytokine and chemokine expression and apoptosis in macrophages, Virus Research, 160, 1-2, 2011. Crossref

  27. Haas Christian S., Amin M. Asif, Allen Brittany B., Ruth Jeffrey H., Haines G. Kenneth, Woods James M., Koch Alisa E., Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis, Arthritis & Rheumatism, 54, 8, 2006. Crossref

  28. Fuschiotti Patrizia, Role of IL-13 in systemic sclerosis, Cytokine, 56, 3, 2011. Crossref

  29. Ruiz C., Pérez E., García-Martínez O., Díaz-Rodríguez L., Arroyo-Morales M., Reyes-Botella C., Expression of cytokines IL-4, IL-12, IL-15, IL-18, and IFNγ and modulation by different growth factors in cultured human osteoblast-like cells, Journal of Bone and Mineral Metabolism, 25, 5, 2007. Crossref

  30. Lee Hansongyi, Lee In Seok, Choue Ryowon, Obesity, Inflammation and Diet, Pediatric Gastroenterology, Hepatology & Nutrition, 16, 3, 2013. Crossref

  31. Sun L.-Z., Elsayed S., Bronstad A. M., Van Do T., Irgens Å., Aardal N. P., Aasen T. B., Airway Inflammation and Bronchial Remodelling in Toluene Diisocyanate-exposed BALB/c Mouse Model, Scandinavian Journal of Immunology, 65, 2, 2007. Crossref

  32. Wilankar Chandan, Sharma Deepak, Checker Rahul, Khan Nazir M., Patwardhan Raghavendra, Patil Anand, Sandur Santosh Kumar, Devasagayam T.P.A., Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols, Free Radical Biology and Medicine, 51, 1, 2011. Crossref

  33. Li , Masucci , Levitsky , Effect of Interleukin-7 on the In Vitro Development and Maturation of Monocyte Derived Human Dendritic Cells, Scandinavian Journal of Immunology, 51, 4, 2000. Crossref

  34. Komiyama Hidenori, Miyake Koichi, Asai Kuniya, Mizuno Kyoichi, Shimada Takashi, Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells, Cell Biochemistry and Function, 32, 1, 2014. Crossref

  35. Lee Dae Hwan, Ahn Ji Hyeon, Park Joon Ha, Yan Bing Chun, Cho Jeong-Hwi, Kim In Hye, Lee Jae-Chul, Jang Sang-Hun, Lee Myoung Hyo, Hwang In Koo, Moon Seung Myung, Lee Bonghee, Cho Jun Hwi, Shin Hyung-Cheul, Kim Jin Sang, Won Moo-Ho, Comparison of Expression of Inflammatory Cytokines in the Spinal Cord Between Young Adult and Aged Beagle Dogs, Cellular and Molecular Neurobiology, 33, 5, 2013. Crossref

  36. Loria-Cervera Elsy Nalleli, Sosa-Bibiano Erika Ivett, Villanueva-Lizama Liliana Estefania, Van Wynsberghe Nicole Raymonde, Schountz Tony, Andrade-Narvaez Fernando Jose, Cloning and sequence analysis of Peromyscus yucatanicus (Rodentia) Th1 (IL-12p35, IFN-γ and TNF) and Th2 (IL-4, IL-10 and TGF-β) cytokines, Cytokine, 65, 1, 2014. Crossref

  37. Di Nuzzo Sergio, Sylva-Steenland Regien M. R., Koomen Cornelis W., Nakagawa Satoshi, van Breemen Marielle, de Rie Menno A., Das Pranab K., Bos Jan D., Teunissen Marcel B. M., UVB Irradiation of Normal Human Skin Favors the Development of Type-2 T-cells In Vivo and in Primary Dermal Cell Cultures¶, Photochemistry and Photobiology, 76, 3, 2002. Crossref

  38. Selmi Carlo, Mao Tin K., Keen Carl L., Schmitz Harold H., Eric Gershwin M., The Anti-inflammatory Properties of Cocoa Flavanols, Journal of Cardiovascular Pharmacology, 47, Supplement 2, 2006. Crossref

  39. Lovatel Gisele Agustini, Elsner Viviane Rostirola, Bertoldi Karine, Vanzella Cláudia, Moysés Felipe dos Santos, Vizuete Adriana, Spindler Christiano, Cechinel Laura Reck, Netto Carlos Alexandre, Muotri Alysson Renato, Siqueira Ionara Rodrigues, Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus, Neurobiology of Learning and Memory, 101, 2013. Crossref

  40. Wu Zonglin, Pearson Alex, Oliveira David, Characterization ofcis-regulatory elements conferring mercury-induced interleukin-4 gene expression in rat mast cells: a role for signal transducer and activator of transcription 6 and TATA box binding sites, Immunology, 127, 4, 2009. Crossref

  41. Fan Jiang Ping, Choi Kyoung Min, Han Gi Dong, Inhibitory effects of water extracts of fermented rice bran on allergic response, Food Science and Biotechnology, 19, 6, 2010. Crossref

  42. Gao Jian-Xin, Zhang Jian, Awaraji Christian, Bhatia Mickie, Jevnikar Anthony, Singh Bhagirath, Bell David, Delovitch Terry L., Preferential Proliferation and Differentiation of Double-Positive Thymocytes into CD8+ Single-Positive Thymocytes in a Novel Cell Culture Medium, Cellular Immunology, 202, 1, 2000. Crossref

  43. Yang Xiao Yi, Wang Li Hua, Farrar William L., A Role for PPARγin the Regulation of Cytokines in Immune Cells and Cancer, PPAR Research, 2008, 2008. Crossref

  44. Gourley Tania, Roys Stacey, Lukacs Nicholas W, Kunkel Steven L, Flavell Richard A, Chang Cheong-Hee, A Novel Role for the Major Histocompatibility Complex Class II Transactivator CIITA in the Repression of IL-4 Production, Immunity, 10, 3, 1999. Crossref

  45. Dhanda Sandeep Kumar, Gupta Sudheer, Vir Pooja, Raghava G. P. S., Prediction of IL4 Inducing Peptides, Clinical and Developmental Immunology, 2013, 2013. Crossref

  46. Leng Jianhang, Yao Hangping, Shen Junya, Wang Keyi, Zhuo Guangchao, Wang Ziwei, Co-expression of IL-18 binding protein and IL-4 regulates Th1/Th2 cytokine response in murine collagen-induced arthritis, Acta Biochimica et Biophysica Sinica, 40, 2, 2008. Crossref

  47. MAO T.K., VAN DE WATER J., GERSHWIN M.E., Effect of Spirulina on the Secretion of Cytokines from Peripheral Blood Mononuclear Cells, Journal of Medicinal Food, 3, 3, 2000. Crossref

  48. Yu Yizhi, Cao Xuetao, Zhang Minghui, Lei Hong, Tao Qun, The humoral antitumor responses induced by IL-4 gene-modified tumor vaccine, Chinese Journal of Cancer Research, 9, 4, 1997. Crossref

  49. Mcdonald Christine, Reich Nancy C., Cooperation of the Transcriptional Coactivators CBP and p300 with Stat6, Journal of Interferon & Cytokine Research, 19, 7, 1999. Crossref

  50. Mao T. K., Powell J. J., van de Water J., Keen C. L., Schmitz H. H., Gershwin M. E., Effect of Cocoa Procyanidins on the Secretion of Interleukin-4 in Peripheral Blood Mononuclear Cells, Journal of Medicinal Food, 3, 2, 2000. Crossref

  51. Burke Thomas F., Casolaro Vincenzo, Georas Steve N., Characterization of P5, a Novel NFAT/AP-1 Site in the Human IL-4 Promoter, Biochemical and Biophysical Research Communications, 270, 3, 2000. Crossref

  52. Nuzzo Sergio, Sylva-Steenland Regien M. R., Koomen Cornelis W., Nakagawa Satoshi, Breemen Marielle, Rie Menno A., Das Pranab K., Bos Jan D., Teunissen Marcel B. M., UVB Irradiation of Normal Human Skin Favors the Development of Type-2 T-cells In Vivo and in Primary Dermal Cell Cultures¶, Photochemistry and Photobiology, 76, 3, 2002. Crossref

  53. McDonald Christine, Vanscoy Sarah, Hearing Patrick, Reich Nancy C., Induction of Genes Involved in Cell Cycle Progression by Interleukin-4, Journal of Interferon & Cytokine Research, 24, 12, 2004. Crossref

  54. Kondoh Masatoshi, Hayashi Atsushi, Okamori Mariko, Motonaga Chie, Enomoto Tadao, Cheng Lei, Shimada Takashi, Effects of Enterococcus sp. isolated from deep seawater on inhibition of allergic responses in mice, British Journal of Nutrition, 102, 1, 2008. Crossref

  55. Kim TaeHo, Park KiMoon, Jung Hye Sun, Kong Won-Sik, Jeon DaeHoon, Lee Seung Ho, Evaluation of Anti-atopic Dermatitis Activity ofHypsizigus marmoreusExtract, Phytotherapy Research, 28, 10, 2014. Crossref

  56. Lidström C., Matthiesen L., Berg G., Sharma S., Ernerudh J., Ekerfelt C., Cytokine Secretion Patterns of NK Cells and Macrophages in Early Human Pregnancy Decidua and Blood: Implications for Suppressor Macrophages in Decidua, American Journal of Reproductive Immunology, 50, 6, 2003. Crossref

  57. PAFFEN E., MEDINA P., DE VISSER M. C. H., VAN WIJNGAARDEN A., ZORIO E., ESTELLÉS A., ROSENDAAL F. R., ESPAÑA F., BERTINA R. M., DOGGEN C. J. M., The −589C>T polymorphism in the interleukin-4 gene (IL-4) is associated with a reduced risk of myocardial infarction in young individuals, Journal of Thrombosis and Haemostasis, 6, 10, 2008. Crossref

  58. Sivangala R., Ponnana M., Thada S., Joshi L., Ansari S., Hussain H., Valluri V., Gaddam S., Association of Cytokine Gene Polymorphisms in Patients with Tuberculosis and Their Household Contacts, Scandinavian Journal of Immunology, 79, 3, 2014. Crossref

  59. Hauser Russ, Rice Timothy M, Krishna Murthy G G, Wand Matt P, Lewis Daniel, Bledsoe Toni, Paulauskis Joseph, The upper airway response to pollen is enhanced by exposure to combustion particulates: a pilot human experimental challenge study., Environmental Health Perspectives, 111, 4, 2003. Crossref

  60. Nagai Hiroichi, Ueda Yoshifumi, Ochi Takashi, Hirano Yosuke, Tanaka Hiroyuki, Inagaki Naoki, Kawada Kenji, Different role of IL-4 in the onset of hapten-induced contact hypersensitivity in BALB/c and C57BL/6 mice, British Journal of Pharmacology, 129, 2, 2000. Crossref

  61. Deshmane Satish L., Kremlev Sergey, Amini Shohreh, Sawaya Bassel E., Monocyte Chemoattractant Protein-1 (MCP-1): An Overview, Journal of Interferon & Cytokine Research, 29, 6, 2009. Crossref

  62. Huang DeRen, Wang Jintang, Kivisakk Pia, Rollins Barrett J., Ransohoff Richard M., Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis, Journal of Experimental Medicine, 193, 6, 2001. Crossref

  63. Chomarat Pascale, Banchereau Jacques, Interleukin-4 and lnterleukin-13: Their Similarities and Discrepancies, International Reviews of Immunology, 17, 1-4, 1998. Crossref

  64. Lieberson Rebecca, Mowen Kerri A., McBride Kathryn D., Leautaud Veronica, Zhang Xiankui, Suh Woong-Kyung, Wu Lin, Glimcher Laurie H., Tumor Necrosis Factor Receptor–Associated Factor (Traf)2 Represses the T Helper Cell Type 2 Response through Interaction with Nfat-Interacting Protein (Nip45), Journal of Experimental Medicine, 194, 1, 2001. Crossref

  65. Webber Steven A., Bentlejewski Carol, Boyle Gerard J., Miller Susan A., Law Yuk, Murali Srinivas, Pham Si, Park Andrew, Griffith Bartley P., Duquesnoy Renee, Zeevi Adriana, Propagation of activated T lymphocytes from endomyocardial biopsy samples of cardiac allografts: Influence of the addition of recombinant interleukin-4 to the culture environment, Pediatric Transplantation, 6, 2, 2002. Crossref

  66. Pacor Sabrina, Gagliardi Renato, Spessotto Paola, Zabucchi Giuliano, Sava Gianni, Paracrine effects of IL- 4 transfection on TS/A adenocarcinoma cells mediate reducedin Vivo growth, Pathology & Oncology Research, 5, 2, 1999. Crossref

  67. Yin Shutong, Zhang Yuanyuan, Gao Rui, Cheng Baojing, Shan Anshan, The immunomodulatory effects induced by dietary Zearalenone in pregnant rats, Immunopharmacology and Immunotoxicology, 36, 3, 2014. Crossref

  68. Agarwal Suneet, Rao Anjana, Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation, Immunity, 9, 6, 1998. Crossref

  69. Gabriel Gülsah, Nordmann Alexandra, Stein David A., Iversen Patrick L., Klenk Hans-Dieter, Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus, Journal of General Virology , 89, 4, 2008. Crossref

  70. Di Filippo C., Rossi C., Ferraro B., Maisto R., De Angelis A., Ferraraccio F., Rotondo A., D’Amico M., Involvement of Proteasome and Macrophages M2 in the Protection Afforded by Telmisartan against the Acute Myocardial Infarction in Zucker Diabetic Fatty Rats with Metabolic Syndrome, Mediators of Inflammation, 2014, 2014. Crossref

  71. Walczak-Drzewiecka Aurelia, Wyczólkowska Janina, Dastych Jaroslaw, Environmentally relevant metal and transition metal ions enhance Fc epsilon RI-mediated mast cell activation., Environmental Health Perspectives, 111, 5, 2003. Crossref

  72. Zhang Hangjun, Fang Wendi, Wang Dandan, Gao Nana, Ding Ying, Chen Chao, The role of interleukin family in perfluorooctanoic acid (PFOA)-induced immunotoxicity, Journal of Hazardous Materials, 280, 2014. Crossref

  73. Slavish Danica C., Graham-Engeland Jennifer E., Smyth Joshua M., Engeland Christopher G., Salivary markers of inflammation in response to acute stress, Brain, Behavior, and Immunity, 44, 2015. Crossref

  74. Reilly C.A., Neurogenic Inflammation: TRP Ion Channels in the Lung, in Comprehensive Toxicology, 2010. Crossref

  75. Rogan David F., Cousins David J., Staynov Dontcho Z., Intergenic Transcription Occurs throughout the Human IL-4/IL-13 Gene Cluster, Biochemical and Biophysical Research Communications, 255, 3, 1999. Crossref

  76. Moon Sunhee, Shin Seulmee, Kim Seulah, Oh Hee-Eun, Han Shinha, Lee Seungjeong, Kim Kyungjae, Role ofSalvia miltiorrhizafor Modulation of Th2-derived Cytokines in the Resolution of Inflammation, Immune Network, 11, 5, 2011. Crossref

  77. Solymar Deborah C., Agarwal Suneet, Bassing Craig H., Alt Frederick W., Rao Anjana, A 3′ Enhancer in the IL-4 Gene Regulates Cytokine Production by Th2 Cells and Mast Cells, Immunity, 17, 1, 2002. Crossref

  78. Dahl A. Maria, Klein Christoph, Andres Pietro G., London Cheryl A., Lodge Michael P., Mulligan Richard C., Abbas Abul K., Expression of Bcl-XL Restores Cell Survival, but Not Proliferation and Effector Differentiation, in Cd28-Deficient T Lymphocytes, Journal of Experimental Medicine, 191, 12, 2000. Crossref

  79. Mohrs Katja, Wakil Adil E., Killeen Nigel, Locksley Richard M., Mohrs Markus, A Two-Step Process for Cytokine Production Revealed by IL-4 Dual-Reporter Mice, Immunity, 23, 4, 2005. Crossref

  80. Song Sooyeon, Oh Sejong, Lim Kye-Taek, The glycoprotein (18 kDa) isolated from Lactobacillus plantarum L67 suppressed ß-hexosaminidase, histamine, and the expression of TNF-α and IL-4 in the BPA-stimulated RBL-2H3 cells, Process Biochemistry, 51, 1, 2016. Crossref

  81. Gabriel Gülsah, Klingel Karin, Planz Oliver, Bier Katja, Herwig Astrid, Sauter Martina, Klenk Hans-Dieter, Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus, The American Journal of Pathology, 175, 3, 2009. Crossref

  82. Agarwal Suneet, Avni Orly, Rao Anjana, Cell-Type-Restricted Binding of the Transcription Factor NFAT to a Distal IL-4 Enhancer In Vivo, Immunity, 12, 6, 2000. Crossref

  83. Yadav Amita, Saini Vandana, Arora Sarika, MCP-1: Chemoattractant with a role beyond immunity: A review, Clinica Chimica Acta, 411, 21-22, 2010. Crossref

  84. Gu Y. Stephanie, Kong James, Cheema Gurtej S., Keen Carl L., Wick Georg, Gershwin M. Eric, The Immunobiology of Systemic Sclerosis, Seminars in Arthritis and Rheumatism, 38, 2, 2008. Crossref

  85. Valapour Maryam, Guo Jia, Schroeder John T., Keen Judith, Cianferoni Antonella, Casolaro Vincenzo, Georas Steve N., Histone deacetylation inhibits IL4 gene expression in T cells, Journal of Allergy and Clinical Immunology, 109, 2, 2002. Crossref

  86. Griffin D.E., Cytokines and Chemokines, in Encyclopedia of Virology, 2008. Crossref

  87. Rumalla Vishnu K., Borah Gregory L., Cytokines, Growth Factors, and Plastic Surgery, Plastic and Reconstructive Surgery, 108, 3, 2001. Crossref

  88. Bandeira-Melo Christianne, Hall John C., Penrose John F., Weller Peter F., Cysteinyl leukotrienes induce IL-4 release from cord blood–derived human eosinophils, Journal of Allergy and Clinical Immunology, 109, 6, 2002. Crossref

  89. Lee Jin, Oh Phil-Sun, Lim Kye-Taek, Allergy-related cytokines (IL-4 and TNF-α) are induced by Di(2-ethylhexyl) phthalate and attenuated by plant-originated glycoprotein (75 kDa) in HMC-1 cells, Environmental Toxicology, 26, 4, 2011. Crossref

  90. Heller Frank, Fuss Ivan J, Nieuwenhuis Edward E, Blumberg Richard S, Strober Warren, Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells, Immunity, 17, 5, 2002. Crossref

  91. Arpa Luis, Valledor Annabel F., Lloberas Jorge, Celada Antonio, IL-4 blocks M-CSF-dependent macrophage proliferation by inducing p21Waf1 in a STAT6-dependent way, European Journal of Immunology, 39, 2, 2009. Crossref

  92. Bonder Claudine S., Davies Kate V.L., Liu Xiang, Hertzog Paul J., Woodcock Joanna M., Finlay-Jones John J., Hart Prue H., ENDOGENOUS INTERFERON-α PRODUCTION BY DIFFERENTIATING HUMAN MONOCYTES REGULATES EXPRESSION AND FUNCTION OF THE IL-2/IL-4 RECEPTOR γ CHAIN, Cytokine, 17, 4, 2002. Crossref

  93. Kumar Shantha, Skeen Marianne J., Adiri Yaffa, Yoon Hyseuk, Vezys Vaiva D., Lukacher Aron E., Evavold Brian D., Ziegler H. Kirk, Boss Jeremy M., A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets, Cellular Immunology, 237, 2, 2005. Crossref

  94. Seah G.T, Rook G.A.W, A sensitive, non-radioactive quantitative method for measuring IL-4 and IL-4δ2 mRNA in unstimulated cells from multiple clinical samples, using nested RT-PCR, Journal of Immunological Methods, 228, 1-2, 1999. Crossref

  95. Gupta Sanjay, Jiang Man, Anthony Alissa, Pernis Alessandra B., Lineage-Specific Modulation of Interleukin 4 Signaling by Interferon Regulatory Factor 4, Journal of Experimental Medicine, 190, 12, 1999. Crossref

  96. Razeghifard M.Reza, On-column refolding of recombinant human interleukin-4 from inclusion bodies, Protein Expression and Purification, 37, 1, 2004. Crossref

  97. Ansari A. Wahid, Heiken Hans, Moenkemeyer Maren, Schmidt Reinhold E., Dichotomous effects of C–C chemokines in HIV-1 pathogenesis, Immunology Letters, 110, 1, 2007. Crossref

  98. Tallman Paula Skye, Kuzawa Christopher, Adair Linda, Borja Judith B., McDade Thomas W., Microbial exposures in infancy predict levels of the immunoregulatory cytokine interleukin-4 in filipino young adults, American Journal of Human Biology, 24, 4, 2012. Crossref

  99. Sheu Shwu-Jiuan, Ger Luo-Ping, Kuo Ni-Wen, Liu Ni-Chun, Wu Tsung-Tien, Lin Muh-Chiou, Association of IL-4 gene polymorphism and age-related macular degeneration in Taiwanese adults, Taiwan Journal of Ophthalmology, 2, 2, 2012. Crossref

  100. Keelan Jeffrey A., Sato Timothy A., Mitchell Murray D., Comparative Studies on the Effects of Interleukin-4 and Interleukin-13 on Cytokine and Prostaglandin E2 Production by Amnion-derived WISH Cells, American Journal of Reproductive Immunology, 40, 5, 1998. Crossref

  101. Poynter Matthew E., Mu Hong-Hua, Chen Xiao-Ping, Daynes Raymond A., Activation of NK1.1+T Cellsin Vitroand Their Possible Role in Age-Associated Changes in Inducible IL-4 Production, Cellular Immunology, 179, 1, 1997. Crossref

  102. Cross M.L., Stevenson L.M., Gill H.S., Anti-allergy properties of fermented foods: an important immunoregulatory mechanism of lactic acid bacteria?, International Immunopharmacology, 1, 5, 2001. Crossref

  103. Takahashi Masato, The endothelium in Kawasaki disease: The next frontier, The Journal of Pediatrics, 133, 2, 1998. Crossref

  104. Hodi F. Stephen, Soiffer Robert J., Interleukins, in Encyclopedia of Cancer, 2002. Crossref

  105. Dohan David M., Choukroun Joseph, Diss Antoine, Dohan Steve L., Dohan Anthony J.J., Mouhyi Jaafar, Gogly Bruno, Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part III: Leucocyte activation: A new feature for platelet concentrates?, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 101, 3, 2006. Crossref

  106. Hong Seung-Heon, Jeong Hyun-Ja, Chung Hwan-Suck, Kim Hyung-Ryong, Chae Han-Jung, Shin Taekyun, Seo Youngwan, Kim Hyung-Min, An herbal formula, Herbkines, enhances cytokines production from immune cells, Journal of Ethnopharmacology, 98, 1-2, 2005. Crossref

  107. Goodwin V.J., Sato T.A., Mitchell M.D., Keelan J.A., Anti-inflammatory Effects of Interleukin-4, Interleukin-10, and Transforming Growth Factor-β on Human Placental Cells In Vitro, American Journal of Reproductive Immunology, 40, 5, 1998. Crossref

  108. Rengarajan Jyothi, Szabo Susanne J, Glimcher Laurie H, Transcriptional regulation of Th1/Th2 polarization, Immunology Today, 21, 10, 2000. Crossref

  109. Gould Hannah J., Beavil Rebecca L., IgE, in Encyclopedia of Immunology, 1998. Crossref

  110. Ahirwar Dinesh, Kesarwani Pravin, Manchanda Parmeet Kaur, Mandhani Anil, Mittal Rama Devi, Anti- and proinflammatory cytokine gene polymorphism and genetic predisposition: association with smoking, tumor stage and grade, and bacillus Calmette-Guérin immunotherapy in bladder cancer, Cancer Genetics and Cytogenetics, 184, 1, 2008. Crossref

  111. Park Jin, Kim Seung Hyun, Li Qian, Chang Young-Tae, Kim Tae Sung, Inhibition of interleukin-4 production in activated T cells via the downregulation of AP-1/NF-AT activation by N-lauroyl-d-erythro-sphingosine and N-lauroyl-d-erythro-C20-sphingosine, Biochemical Pharmacology, 71, 8, 2006. Crossref

  112. Holloway A.F., Rao S., Shannon M.F., Regulation of cytokine gene transcription in the immune system, Molecular Immunology, 38, 8, 2002. Crossref

  113. Lee Sung Ho, Cho Young-Chang, Jeong Hyung Min, Kim Kyung Hee, Choi Hyun Jin, Lee Kwang Youl, Kang Bok Yun, Yin-Yang 1 and Yin-Yang 2 exert opposing effects on the promoter activity of interleukin 4, Archives of Pharmacal Research, 39, 4, 2016. Crossref

  114. Jiang H, Liu C, Xu J, Sun B, Pan S, Qiao H, Luo L, Sun X, Gene transfer of interleukin-4 delays acute rejection of splenic allografts in rats, Transplantation Proceedings, 36, 5, 2004. Crossref

  115. Griffin Diane E., CYTOKINES AND CHEMOKINES, in Encyclopedia of Virology, 1999. Crossref

  116. Kryworuchko Marko, Gee Katrina, Diaz-Mitoma Francisco, Kumar Ashok, Regulation of CD44–Hyaluronan Interactions in Burkitt's Lymphoma and Epstein–Barr Virus-Transformed Lymphoblastoid B Cells by PMA and Interleukin-4, Cellular Immunology, 194, 1, 1999. Crossref

  117. Hayashi M., Higashi K., Kato H., Kaneko H., Assessment of Preferential Th1 or Th2 Induction by Low-Molecular-Weight Compounds Using a Reverse Transcription–Polymerase Chain Reaction Method: Comparison of Two Mouse Strains, C57BL/6 and Balb/c, Toxicology and Applied Pharmacology, 177, 1, 2001. Crossref

  118. Londhe Priya, Guttridge Denis C., Inflammation induced loss of skeletal muscle, Bone, 80, 2015. Crossref

  119. Mena Angelo, Ioannou Xenia P., Van Kessel Andrew, Van Drunen Little-Van Den Hurk Sylvia, Popowych Yurij, Babiuk Lorne A., Godson Dale L., Th1/Th2 biasing effects of vaccination in cattle as determined by real-time PCR, Journal of Immunological Methods, 263, 1-2, 2002. Crossref

  120. Hantoushzadeh Sedigheh, Javadian Pouya, Salmanian Bahram, Ghazanfari Tooba, Kermani Arezou, Abbasalizadeh Fatemeh, Zandevakil Farahnaz, Khazardoost Soghra, Betamethasone effects on the endocervical inflammatory cytokines in preterm labor: A randomized clinical trial, International Immunopharmacology, 11, 8, 2011. Crossref

  121. Megyeri Klára, Mándi Yvette, Degré Miklos, Rosztóczy István, INDUCTION OF CYTOKINE PRODUCTION BY DIFFERENT STAPHYLOCOCCAL STRAINS, Cytokine, 19, 4, 2002. Crossref

  122. Nohara Keiko, Fujimaki Hidekazu, Tsukumo Shin-ichi, Inouye Kaoru, Sone Hideko, Tohyama Chiharu, Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on T cell-derived cytokine production in ovalbumin (OVA)-immunized C57Bl/6 mice, Toxicology, 172, 1, 2002. Crossref

  123. Lin Mark T., Hinton David R., Parra Beatriz, Stohlman Stephen A., van der Veen Roel C., The Role of IL-10 in Mouse Hepatitis Virus-Induced Demyelinating Encephalomyelitis, Virology, 245, 2, 1998. Crossref

  124. Huang DeRen, Xia ShiQin, Zhou YiHua, Pirskanen Ritva, Liu Li, Lefvert Ann Kari, No evidence for interleukin-4 gene conferring susceptibility to myasthenia gravis, Journal of Neuroimmunology, 92, 1-2, 1998. Crossref

  125. Lev Bar-Or Ruth, Feedback mechanisms between T helper cells and macrophages in the determination of the immune response, Mathematical Biosciences, 163, 1, 2000. Crossref

  126. Walter Wolfgang, Loos Michael, Maeurer Markus J, Differential expression of alternative H2-M isoforms in B cells, dendritic cells and macrophages by proinflammatory cytokines, Molecular Immunology, 36, 11-12, 1999. Crossref

  127. Toben Daniel, Schroeder Ireen, El Khassawna Thaqif, Mehta Manav, Hoffmann Jan-Erik, Frisch Jan-Tilmann, Schell Hanna, Lienau Jasmin, Serra Alessandro, Radbruch Andreas, Duda Georg N, Fracture healing is accelerated in the absence of the adaptive immune system, Journal of Bone and Mineral Research, 26, 1, 2011. Crossref

  128. Lee Gap Ryol, Fields Patrick E., Flavell Richard A., Regulation of IL-4 Gene Expression by Distal Regulatory Elements and GATA-3 at the Chromatin Level, Immunity, 14, 4, 2001. Crossref

  129. Jeong Hyun-Ja, Chung Hwan-Suck, An Hyo-Jin, Kim Joon-Bae, Lee Eun-Mi, Park Eun-Jeong, Jang Chul-Ho, Hong Seung-Heon, Kim Hyung-Min, Immune-enhancement effect of the herbal combination Allergina, Clinica Chimica Acta, 337, 1-2, 2003. Crossref

  130. Alzolibani Abdullateef A., Al Robaee Ahmad A., Al Shobaili Hani A., Saif Ghada Bin, Al-Saif Fahad, Ali Ahmed, Settin Ahmad, Interleukin-4 −590 T>C and interleukin-4 receptor Q551R A>G gene polymorphisms in Saudi cases with alopecia areata, Journal of the Egyptian Public Health Association, 90, 1, 2015. Crossref

  131. Marino Mariapaola, Scuderi Flavia, Mazzarelli Paola, Mannella Francesca, Provenzano Carlo, Bartoccioni Emanuela, Constitutive and cytokine-induced expression of MHC and intercellular adhesion molecule-1 (ICAM-1) on human myoblasts, Journal of Neuroimmunology, 116, 1, 2001. Crossref

  132. Song Xiaoyu, Zhou Biao, Cui Lingyu, Lei Di, Zhang Pingping, Yao Guodong, Xia Mingyu, Hayashi Toshihiko, Hattori Shunji, Ushiki-Kaku Yuko, Tashiro Shin-ichi, Onodera Satoshi, Ikejima Takashi, Silibinin ameliorates Aβ25-35-induced memory deficits in rats by modulating autophagy and attenuating neuroinflammation as well as oxidative stress, Neurochemical Research, 42, 4, 2017. Crossref

  133. Wolkow Alexander, Ferguson Sally A., Vincent Grace E., Larsen Brianna, Aisbett Brad, Main Luana C., Lutter Rene, The Impact of Sleep Restriction and Simulated Physical Firefighting Work on Acute Inflammatory Stress Responses, PLOS ONE, 10, 9, 2015. Crossref

  134. Jeong Hyun‐Ja, Kang Sei‐Young, Kim Sang‐Yong, Lee Sang‐Gwan, Lee Sung‐Geun, Sung Kang‐Keyng, Kim Hyung‐Min, The Effect of Jeo Dang‐Tang on Cytokines Production in the Patients with Cerebral Infarction, Immunopharmacology and Immunotoxicology, 25, 4, 2003. Crossref

  135. Nursal Ayse Feyda, Tekcan Akin, Kaya Suheyla Uzun, Sezer Ozlem, Yigit Serbulent, Interleukin-1Ra rs2234663 and Interleukin-4 rs79071878 Polymorphisms in Familial Mediterranean Fever, Gene, 582, 2, 2016. Crossref

  136. Bandeira-Melo Christianne, Woods Lesley J., Phoofolo Mojabeng, Weller Peter F., Intracrine Cysteinyl Leukotriene Receptor–mediated Signaling of Eosinophil Vesicular Transport–mediated Interleukin-4 Secretion, Journal of Experimental Medicine, 196, 6, 2002. Crossref

  137. Tsujimura Yusuke, Yasutomi Yasuhiro, Allergy Vaccines Using a Mycobacterium-Secreted Antigen, Ag85B, and an IL-4 Antagonist, in Vaccine Design, 1403, 2016. Crossref

  138. Rubio-Perez Jose Miguel, Morillas-Ruiz Juana Maria, A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines, The Scientific World Journal, 2012, 2012. Crossref

  139. Okada Annabelle A., Sakai Jun-ichi, Usui Masahiko, Mizuguchi J. Junichiro, Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats, Ocular Immunology and Inflammation, 6, 2, 1998. Crossref

  140. Cuvelier Susan L. , Patel Kamala D. , Shear-dependent Eosinophil Transmigration on Interleukin 4–stimulated Endothelial Cells , Journal of Experimental Medicine, 194, 12, 2001. Crossref

  141. Jamalidoust Marzieh, Ravanshad Mehrdad, Namayandeh Mandana, Zare Maryam, Asaei Sadaf, Ziyaeyan Mazyar, Construction of AAV-rat-IL4 and Evaluation of its Modulating Effect on Aβ (1-42)-Induced Proinflammatory Cytokines in Primary Microglia and the B92 Cell Line by Quantitative PCR Assay, Jundishapur Journal of Microbiology, 9, 3, 2016. Crossref

  142. Alam Rasha T., Zeid Ehsan H. Abu, Imam Tamer S., Protective role of quercetin against hematotoxic and immunotoxic effects of furan in rats, Environmental Science and Pollution Research, 24, 4, 2017. Crossref

  143. Opal Steven M., DePalo Vera A., Anti-Inflammatory Cytokines, Chest, 117, 4, 2000. Crossref

  144. Farrar William L., Interleukin-4, in Encyclopedia of Cancer, 2011. Crossref

  145. Xu L-Y, Huang Y-M, Yang J-S, Van Der Meide P H, Levi M, Wahren B, Link H, Xiao B-G, Dendritic cell-derived nitric oxide is involved in IL-4-induced suppression of experimental allergic encephalomyelitis (EAE) in Lewis rats, Clinical and Experimental Immunology, 118, 1, 2001. Crossref

  146. Do Hyun Ju, Oh Tae Woo, Yang Ju Hye, Park Kwang Il, Ma Jin Yeul, Davallia mariesiiMoore Improves FcεRI-Mediated Allergic Responses in the Rat Basophilic Leukemia Mast Cell Line RBL-2H3 and Passive Cutaneous Anaphylaxis in Mice, Mediators of Inflammation, 2017, 2017. Crossref

  147. Vos Quirijn, Snapper Clifford M., Mond James J., Th1 versus Th2 cytokine profile determines the modulation of in vitro T cell-independent type 2 responses by IL-4, International Immunology, 12, 9, 2000. Crossref

  148. Shao Xueting, Qian Yun, Xu Chenhuai, Hong Bo, Xu Wanhong, Shen Ling, Jin Changzhong, Wu Zhigang, Tong Xiangmin, Yao Hangping, Ryffel Bernhard, The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on ConA-Induced Hepatitis in Mice, PLoS ONE, 8, 3, 2013. Crossref

  149. Beach T M, Whalen M M, Effects of organochlorine pesticides on interleukin secretion from lymphocytes, Human & Experimental Toxicology, 25, 11, 2006. Crossref

  150. Elias Dana, Tikochinski Yaron, Frankel Gad, Cohen Irun R., Regulation of NOD mouse autoimmune diabetes by T cells that recognize a TCR CDR3 peptide, International Immunology, 11, 6, 1999. Crossref

  151. Farrar William L., Interleukin-4, in Encyclopedia of Cancer, 2017. Crossref

  152. Blalock Emily L., Chien Hsin, Dix Richard D., Systemic Reduction of Interleukin-4 or Interleukin-10 Fails to Reduce the Frequency or Severity of Experimental Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression, Ophthalmology and Eye Diseases, 4, 2012. Crossref

  153. Al Robaee Ahmad A., AlZolibani Abdullateef, Al Shobaili Hani, Settin Ahmad, Association of interleukin 4 (-590 T/C) and interleukin 4 receptor (Q551R A/G) gene polymorphisms with acne vulgaris, Annals of Saudi Medicine, 32, 4, 2012. Crossref

  154. Wu Zhonglin, Turner David R., Oliveira David B. G., IL-4 gene expression up-regulated by mercury in rat mast cells: a role of oxidant stress in IL-4 transcription, International Immunology, 13, 3, 2001. Crossref

  155. Fu Meng, Fu Shulian, Ni Saihong, Zou Liyuan, Liu Yumei, Hong Tie, Anti-inflammatory effect of epigallocatechin gallate in a mouse model of ovalbumin-induced allergic rhinitis, International Immunopharmacology, 49, 2017. Crossref

  156. Deering-Rice C.E., Reilly C.A., Neurogenic Inflammation: TRP Ion Channels in the Lung, in Comprehensive Toxicology, 2018. Crossref

  157. Yea Sung Su, Yang Young-Il, Park Seong Kook, Jang Won Hee, Lee Sang Seop, Seog Dae-Hyun, Park Yeong-Hong, Chun Jin Ho, Interleukin-4 C-590T Polymorphism is associated with Protection against Nasal Polyps in a Korean Population, American Journal of Rhinology, 20, 5, 2006. Crossref

  158. Mosmann Tim, Complexity or coherence? Cytokine secretion by B cells, Nature Immunology, 1, 6, 2000. Crossref

  159. Mao T.K., Water J. Van de, Gershwin M.E., Effects of a Spirulina-Based Dietary Supplement on Cytokine Production from Allergic Rhinitis Patients, Journal of Medicinal Food, 8, 1, 2005. Crossref

  160. Srivastava Rajnish, Chaudhary Deepa, Nagar Hemant, Chandel Harinarayan Singh, WITHDRAWN: Anti-allergic activity of ethanol extractives of Quisqualis Indica Linn. by in-vitro compound 48/80 induced mast cell degranulation and in-vivo passive cutaneous anaphylaxis (PCA) model, Toxicology Reports, 2018. Crossref

  161. Mackay Fabienne, Browning Jeffrey L., BAFF: A fundamental survival factor for B cells, Nature Reviews Immunology, 2, 7, 2002. Crossref

  162. Mao Tin, Van de Water Judy, Keen Carl L., Schmitz Harold H., Gershwin M. Eric, Cocoa Procyanidins and Human Cytokine Transcription and Secretion, The Journal of Nutrition, 130, 8, 2000. Crossref

  163. Wang Kexin, Song Feng, Fernandez-Escobar Alejandro, Luo Gang, Wang Jun-Hui, Sun Yu, The Properties of Cytokines in Multiple Sclerosis: Pros and Cons, The American Journal of the Medical Sciences, 356, 6, 2018. Crossref

  164. Guo Rui Hong, Park Jung Up, Jo Se Jin, Ahn Jae Hun, Park Jong Hwan, Yang Ji Yoon, Lee Sung Suk, Park Mi Jin, Kim Young Ran, Anti-allergic Inflammatory Effects of the Essential Oil From Fruits of Zanthoxylum coreanum Nakai, Frontiers in Pharmacology, 9, 2018. Crossref

  165. Melo Ashanty M, Zhang Lei, Dockry Éilis F, Petrasca Andreea, Ghnewa Yasmeen G, Breen Eamon P, Morrissey Maria E, O’Reilly Ciara, Bruen Robyn, O’Meara Andrew, Lysaght Joanne, Zhu Xiangming, Doherty Derek G, Novel thioglycoside analogs of α-galactosylceramide stimulate cytotoxicity and preferential Th1 cytokine production by human invariant natural killer T cells, Glycobiology, 28, 7, 2018. Crossref

  166. Sangil Anna, Arranz María J., Güerri-Fernández Roberto, Pérez Maite, Monzón Helena, Payeras Antoni, Andrés Marta, Torviso Jorge, Ibañez Laura, Garau Javier, Calbo Esther, Genetic susceptibility to invasive pneumococcal disease, Infection, Genetics and Evolution, 59, 2018. Crossref

  167. Kiyota Tomomi, Okuyama Satoshi, Swan Russell J., Jacobsen Michael T., Gendelman Howard E., Ikezu Tsuneya, CNS expression of anti‐inflammatory cytokine interleukin‐4 attenuates Alzheimer's disease‐like pathogenesis in APP+PS1 bigenic mice, The FASEB Journal, 24, 8, 2010. Crossref

  168. Cakouros Dimitrios, Cockerill Peter N., Bert Andrew G., Mital Renu, Roberts Donna C., Shannon M. Frances, A NF-κB/Sp1 Region Is Essential for Chromatin Remodeling and Correct Transcription of a Human Granulocyte- Macrophage Colony-Stimulating Factor Transgene, The Journal of Immunology, 167, 1, 2001. Crossref

  169. Grodzinsky Ewa, Sund Levander Märta, Physiological and Immunological Activity, in Understanding Fever and Body Temperature, 2020. Crossref

  170. Sciacca F. L., Grimaldi L. M. E., Cytokine Genes in Multiple Sclerosis, in From Basic Immunology to Immune-Mediated Demyelination, 1999. Crossref

  171. MacNeil Adam J., Yang Yong Jun, Lin Tong-Jun, MAPK Kinase 3 Specifically Regulates FcεRI-Mediated IL-4 Production by Mast Cells, The Journal of Immunology, 187, 6, 2011. Crossref

  172. Meena Anbalagan A., Murugesan Amudhan, Sopnajothi Surliappan, Yong Yean K., Ganesh P. Sankar, Vimali Irudhayaraj J., Vignesh Ramachandran, Elanchezhiyan Manickan, Kannan Meganathan, Dash Aditya P., Shankar Esaki M., Increase of Plasma TNF-α Is Associated with Decreased Levels of Blood Platelets in Clinical Dengue Infection, Viral Immunology, 33, 1, 2020. Crossref

  173. Buzás Krisztina, Megyeri Klára, Miczák A., Fekete Andrea, Degré M., Mándi Yvette, Rosztóczy I., Different Staphylococcal Strains Elicit Different Levels of Production of t-helper 1-inducing Cytokines, Acta Microbiologica et Immunologica Hungarica, 51, 3, 2004. Crossref

  174. Sherman Melanie A., Brown Melissa A., Regulation of IL-4 Expression in Mast Cells, in Signal Transduction in Mast Cells and Basophils, 1999. Crossref

  175. Keisari Yona, Robin Guy, Nissimov Liat, Wang Hongbin, Mesika Adi, Dimri Rachel, Ofek Itzhak, Role of Cytokines in the Maturation and Function of Macrophages, in The Biology and Pathology of Innate Immunity Mechanisms, 479, 2002. Crossref

  176. Wang Li Hua, Kirken Robert A., Yang Xiao Yi, Erwin Rebecca A., DaSilva Luis, Yu Cheng-Rong, Farrar William L., Selective disruption of interleukin 4 autocrine-regulated loop by a tyrosine kinase inhibitor restricts activity of T-helper 2 cells, Blood, 95, 12, 2000. Crossref

  177. Teunissen Marcel B. M., Piskin Gamze, Nuzzo Sergio di, Sylva-Steenland Regien M. R., de Rie Menno A., Bos Jan D., Ultraviolet B Radiation Induces a Transient Appearance of IL-4+ Neutrophils, Which Support the Development of Th2 Responses, The Journal of Immunology, 168, 8, 2002. Crossref

  178. Sawaguchi Minoru, Tanaka Shinya, Nakatani Yuriko, Harada Yasuyo, Mukai Kaori, Matsunaga Yuko, Ishiwata Kenji, Oboki Keisuke, Kambayashi Taku, Watanabe Naohiro, Karasuyama Hajime, Nakae Susumu, Inoue Hiromasa, Kubo Masato, Role of Mast Cells and Basophils in IgE Responses and in Allergic Airway Hyperresponsiveness, The Journal of Immunology, 188, 4, 2012. Crossref

  179. References, in Immunotoxicology and Risk Assessment, 2002. Crossref

  180. Farrar William L., Interleukin-4, in Encyclopedia of Cancer, 2015. Crossref

  181. Calandra T., Heumann D., Inhibitory Cytokines, in Immune Response in the Critically Ill, 2002. Crossref

  182. Butler Noah S., Monick Martha M., Yarovinsky Timur O., Powers Linda S., Hunninghake Gary W., Altered IL-4 mRNA Stability Correlates with Th1 and Th2 Bias and Susceptibility to Hypersensitivity Pneumonitis in Two Inbred Strains of Mice, The Journal of Immunology, 169, 7, 2002. Crossref

  183. Brown Melissa A., IL-4 Production by T Cells: You Need a Little to Get a Lot, The Journal of Immunology, 181, 5, 2008. Crossref

  184. Cianferoni Antonella, Schroeder John T., Kim Jean, Schmidt John W., Lichtenstein Lawrence M., Georas Steve N., Casolaro Vincenzo, Selective inhibition of interleukin-4 gene expression in human T cells by aspirin, Blood, 97, 6, 2001. Crossref

  185. Chung Su Wol, Kang Bok Yun, Kim Tae Sung, Inhibition of Interleukin-4 Production in CD4+ T Cells by Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) Ligands: Involvement of Physical Association between PPAR-γ and the Nuclear Factor of Activated T Cells Transcription Factor, Molecular Pharmacology, 64, 5, 2003. Crossref

  186. Simbirtsev Andrey S., Kozlov Ivan G., Cytokine System, in Mechanical Stretch and Cytokines, 2012. Crossref

  187. Xu Qiming, Xu Wei, Cheng Hao, Yuan Hong, Tan Xiangshi, Efficacy and mechanism of cGAMP to suppress Alzheimer’s disease by elevating TREM2, Brain, Behavior, and Immunity, 81, 2019. Crossref

  188. Woods James M., Katschke Kenneth J., Volin Michael V., Ruth Jeffrey H., Woodruff Drew C., Amin M. Asif, Connors Matthew A., Kurata Hirokazu, Arai Ken-Ichi, Haines G. Kenneth, Kumar Pawan, Koch Alisa E., IL-4 Adenoviral Gene Therapy Reduces Inflammation, Proinflammatory Cytokines, Vascularization, and Bony Destruction in Rat Adjuvant-Induced Arthritis, The Journal of Immunology, 166, 2, 2001. Crossref

  189. Cortes‐Selva Diana, Ready Andrew, Gibbs Lisa, Rajwa Bartek, Fairfax Keke C., IL‐4 promotes stromal cell expansion and is critical for development of a type‐2, but not a type 1 immune response, European Journal of Immunology, 49, 3, 2019. Crossref

  190. Brzoska T., Luger T. A., Murine Models of Atopic Dermatitis, in Animal Models of T Cell-Mediated Skin Diseases, 50, 2005. Crossref

  191. Do Hyun Ju, Hwang Yeo Jin, Yang Hye Jin, Park Kwang Il, Effect of Rhus verniciflua Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice, Evidence-Based Complementary and Alternative Medicine, 2019, 2019. Crossref

  192. Gessner André, Mohrs Katja, Mohrs Markus, Mast Cells, Basophils, and Eosinophils Acquire Constitutive IL-4 and IL-13 Transcripts during Lineage Differentiation That Are Sufficient for Rapid Cytokine Production, The Journal of Immunology, 174, 2, 2005. Crossref

  193. Wang Li Hua, Kirken Robert A., Yang Xiao Yi, Erwin Rebecca A., DaSilva Luis, Yu Cheng-Rong, Farrar William L., Selective disruption of interleukin 4 autocrine-regulated loop by a tyrosine kinase inhibitor restricts activity of T-helper 2 cells, Blood, 95, 12, 2000. Crossref

  194. Rothenberg Ellen V., Gene Regulation in T-Cell Lineage Commitment, in Molecular Biology of B-Cell and T-Cell Development, 1998. Crossref

  195. Chen Rongbing, Burke Thomas F., Cumberland John E., Brummet Mary, Beck Lisa A., Casolaro Vincenzo, Georas Steve N., Glucocorticoids Inhibit Calcium- and Calcineurin-Dependent Activation of the Human IL-4 Promoter, The Journal of Immunology, 164, 2, 2000. Crossref

  196. Grogan Jane L., Wang Zhi-En, Stanley Sarah, Harmon Brian, Loots Gaby G., Rubin Edward M., Locksley Richard M., Basal Chromatin Modification at the IL-4 Gene in Helper T Cells, The Journal of Immunology, 171, 12, 2003. Crossref

  197. Bandeira-Melo Christianne, Sugiyama Kumiya, Woods Lesley J., Phoofolo Mojabeng, Center David M., Cruikshank William W., Weller Peter F., IL-16 Promotes Leukotriene C4and IL-4 Release from Human Eosinophils via CD4- and Autocrine CCR3-Chemokine-Mediated Signaling, The Journal of Immunology, 168, 9, 2002. Crossref

  198. Ertl Hildegund C. J., Cytokines and Immunomodulatory Ligands as Genetic Adjuvants, in DNA Vaccines, 2003. Crossref

  199. Hural John A., Kwan Millie, Henkel Greg, Hock M. Benjamin, Brown Melissa A., An Intron Transcriptional Enhancer Element Regulates IL-4 Gene Locus Accessibility in Mast Cells, The Journal of Immunology, 165, 6, 2000. Crossref

  200. Arakawa Tomohiro, Okubo Haruki, Mae Midori, Okuno Tomofumi, Ogino Hirofumi, Ueno Hitoshi, Seleno-L-Methionine Suppresses Immunoglobulin E-Mediated Allergic Response in RBL-2H3 Cells, Biological and Pharmaceutical Bulletin, 42, 7, 2019. Crossref

  201. Bandeira-Melo Christianne, Sugiyama Kumiya, Woods Lesley J., Weller Peter F., Cutting Edge: Eotaxin Elicits Rapid Vesicular Transport-Mediated Release of Preformed IL-4 from Human Eosinophils, The Journal of Immunology, 166, 8, 2001. Crossref

  202. Takemoto Naofumi, Kamogawa Yumiko, Jun Lee Hyun, Kurata Hirokazu, Arai Ken-ichi, O’Garra Anne, Arai Naoko, Miyatake Shoichiro, Cutting Edge: Chromatin Remodeling at the IL-4/IL-13 Intergenic Regulatory Region for Th2-Specific Cytokine Gene Cluster, The Journal of Immunology, 165, 12, 2000. Crossref

  203. Poynter Matthew E., Daynes Raymond A., Restoration of Immunocompetence in Aging and Other Inflammatory Disease States by Dehydroepiandrosterone-3ß-Sulfate, an Activator of the Peroxisome Proliferator-Activated Receptor Alpha (PPARα), in Dehydroepiandrosterone (DHEA), 2000. Crossref

  204. Bı́ró Tamás, Maurer Marcus, Modarres Shayan, Lewin Nancy E., Brodie Chaya, Ács Géza, Ács Péter, Paus Ralf, Blumberg Peter M., Characterization of Functional Vanilloid Receptors Expressed by Mast Cells, Blood, 91, 4, 1998. Crossref

  205. Förtsch Daniela, Röllinghoff Martin, Stenger Steffen, IL-10 Converts Human Dendritic Cells into Macrophage-Like Cells with Increased Antibacterial Activity Against VirulentMycobacterium tuberculosis, The Journal of Immunology, 165, 2, 2000. Crossref

  206. Rumalla Vishnu, Lowry Stephen F., Counterregulation of Severe Inflammation: When More is Too Much and Less is Inadequate, in Multiple Organ Failure, 2000. Crossref

  207. Radeke Heinfried H., Resch Klaus, Molekulare Aspekte der chronischen Entzündung, in Immunsystem und Infektiologie, 1999. Crossref

  208. Mtshali Andile, Ngcapu Sinaye, Osman Farzana, Garrett Nigel, Singh Ravesh, Rompalo Anne, Mindel Adrian, Liebenberg Lenine J P, Genital HSV-1 DNA detection is associated with a low inflammatory profile in HIV-uninfected South African women, Sexually Transmitted Infections, 97, 1, 2021. Crossref

  209. Wu Xianzhu, Thylur Ramesh P., Dayanand Kiran K., Punnath Kishore, Norbury Christopher C., Gowda D. Channe, IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells, The Journal of Immunology, 206, 1, 2021. Crossref

  210. Peng Sandy, Lin Jin-Yuarn, Lin Meei-Yn, Antiallergic Effect of Milk Fermented with Lactic Acid Bacteria in a Murine Animal Model, Journal of Agricultural and Food Chemistry, 55, 13, 2007. Crossref

  211. Lohoff Michael, Giaisi Marco, Köhler Rebecca, Casper Bärbel, Krammer Peter H., Li-Weber Min, Early Growth Response Protein-1 (Egr-1) Is Preferentially Expressed in T Helper Type 2 (Th2) Cells and Is Involved in Acute Transcription of the Th2 Cytokine Interleukin-4, Journal of Biological Chemistry, 285, 3, 2010. Crossref

  212. te Pas Marinus F. W., Park Woncheoul, Srikanth Krishnamoorthy, Kemp Steve, Kim Jun-Mo, Lim Dajeong, Park Jong-Eun, Transcriptomic profiles of muscle, heart, and spleen in reaction to circadian heat stress in Ethiopian highland and lowland male chicken, Cell Stress and Chaperones, 24, 1, 2019. Crossref

  213. Chaudhary Deepa, Srivastava Rajnish, Nagar Hemant, Anti-allergic Assessment of Ethanol Extractives of Quisqualis Indica Linn, Current Bioactive Compounds, 17, 7, 2021. Crossref

  214. Glimcher Laurie H., Murphy Kenneth M., Lineage commitment in the immune system: the T helper lymphocyte grows up, Genes & Development, 14, 14, 2000. Crossref

  215. Ha Dong Jin, Kim Jonggun, Kim Saehun, Go Gwang-Woong, Whang Kwang-Youn, Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after Antigen Exposure, Foods, 10, 1, 2021. Crossref

  216. Chakrabarty Paramita, Tianbai Li, Herring Amanda, Ceballos-Diaz Carolina, Das Pritam, Golde Todd E, Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition, Molecular Neurodegeneration, 7, 1, 2012. Crossref

  217. Zhang Qihong, Mo Guodong, Xie Tingting, Zhang Zihao, Fu Huali, Wei Ping, Zhang Xiquan, Chen Shuai, Phylogenetic Analysis of ALV-J Associated with Immune Responses in Yellow Chicken Flocks in South China, Mediators of Inflammation, 2021, 2021. Crossref

  218. Hsu Wei-Hsuan, Lee Bao-Hong, Hsu Ya-Wen, Pan Tzu-Ming, Inhibition of Th2 Cytokine Production in T Cells by Monascin via PPAR-γ Activation, Journal of Agricultural and Food Chemistry, 61, 34, 2013. Crossref

  219. Srivastava RN, Verma NS, Immunological Response to Post-trauma Bone Remodeling, Journal of Postgraduate Medicine, Education and Research, 46, 3, 2012. Crossref

  220. Nolan Yvonne, Maher Frank O., Martin Darren S., Clarke Rachael M., Brady Miriam T., Bolton Anthony E, Mills Kingston H.G., Lynch Marina A., Role of Interleukin-4 in Regulation of Age-related Inflammatory Changes in the Hippocampus, Journal of Biological Chemistry, 280, 10, 2005. Crossref

  221. Davoodi Akram, Lotfi Ramin, Mortazavi Seyed Hamidreza, Gorgin Karaji Ali, Rezaiemanesh Alireza, Salari Farhad, Retinoic Acid Correlates with Reduced Serum IL-10 And TGF-β in Allergic Rhinitis, Reports of Biochemistry and Molecular Biology, 9, 4, 2021. Crossref

  222. YUN L W P, DECARLO A A, COLLYER C, HUNTER N, Enhancement of Th2 pathways and direct activation of B cells by the gingipains of Porphyromonas gingivalis , Clinical and Experimental Immunology, 134, 2, 2003. Crossref

  223. Kaech Chloé, Bochud Pierre-Yves, Calandra Thierry, Donnenberg Michael S., Cytokines and Escherichia coli Sepsis , EcoSal Plus, 2, 1, 2006. Crossref

  224. Yang Wenbin, Gao Yujing, Wang Xiaojuan, Diffusion modeling of tumor-CD4$ ^+ $-cytokine interactions with treatments: asymptotic behavior and stationary patterns, Discrete & Continuous Dynamical Systems - B, 27, 3, 2022. Crossref

  225. Reece W. H. H., Plebanski M., Akinwunmi P., Gothard P., Flanagan K. L., Lee E. A. M., Cortina-Borja M., Hill A. V. S., Pinder M., Naturally Exposed Populations Differ in Their T1 and T2 Responses to the Circumsporozoite Protein of Plasmodium falciparum , Infection and Immunity, 70, 3, 2002. Crossref

  226. Nordback P.H., Miettinen S., Kääriäinen M., Pelto-Huikko M., Kuokkanen H., Suuronen R., Amniotic membrane reduces wound size in early stages of the healing process, Journal of Wound Care, 21, 4, 2012. Crossref

  227. Hellenthal Femke A. M. V. I., Buurman Willem A., Wodzig Will K. W. H., Schurink Geert Willem H., Biomarkers of abdominal aortic aneurysm progression. Part 2: inflammation, Nature Reviews Cardiology, 6, 8, 2009. Crossref

  228. Yagi Ryouji, Tanaka Shinya, Motomura Yasutaka, Kubo Masato, Regulation of the Il4 Gene Is Independently Controlled by Proximal and Distal 3′ Enhancers in Mast Cells and Basophils , Molecular and Cellular Biology, 27, 23, 2007. Crossref

  229. Higa Shinji, Hirano Toru, Kotani Mayumi, Matsumoto Motonobu, Fujita Akihito, Suemura Masaki, Kawase Ichiro, Tanaka Toshio, Fisetin, a flavonol, inhibits TH2-type cytokine production by activated human basophils, Journal of Allergy and Clinical Immunology, 111, 6, 2003. Crossref

  230. Arinobu Yojiro, Atamas Sergei P., Otsuka Takeshi, Niiro Hiroaki, Yamaoka Kunihiro, Mitsuyasu Hiromichi, Niho Yoshiyuki, Hamasaki Naotaka, White Barbara, Izuhara Kenji, Antagonistic Effects of an Alternative Splice Variant of Human IL-4, IL-4δ2, on IL-4 Activities in Human Monocytes and B Cells, Cellular Immunology, 191, 2, 1999. Crossref

  231. Brandt E, Colombel J-F, Ectors N, Gambiez L, Emilie D, Geboes K, Capron M, Desreumaux P, Enhanced production of IL-8 in chronic but not in early ileal lesions of Crohn's disease (CD), Clinical and Experimental Immunology, 122, 2, 2008. Crossref

  232. Anam Khoirul, Endharti Agustina Tri, Poeranto Sri, Sujuti Hidayat, Hidayati Dwi Yuni Nur, Prawiro Sumarno Reto, Shigella flexneri vaccine development: Oral administration of peptides derived from the 49.8 kDa pili protein subunit activates the intestinal immune response in mice, Veterinary World, 2022. Crossref

  233. Liu Shuyu, Deng Zhenhan, Chen Kang, Jian Shengsheng, Zhou Feifei, Yang Yuan, Fu Zicai, Xie Huanyu, Xiong Jianyi, Zhu Weimin, Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments (Review), Molecular Medicine Reports, 25, 3, 2022. Crossref

  234. Bae Sang Jae, Shimizu Kazuhiro, Yozaki Mariko, Yamaoka Toshifumi, Akiyama Yuichiro, Yoshizaki Ayumi, Muroi Eiji, Hara Toshihide, Ogawa Fumihide, Sato Shinichi, Involvement of L-Selectin in Contact Hypersensitivity Responses Augmented by Auditory Stress, The American Journal of Pathology, 176, 1, 2010. Crossref

  235. MIZRACHI-NEBENZAHL Y, LIFSHITZ S, TEITELBAUM R, NOVICK S, LEVI A, BENHARROCH D, LING E, DAGAN R, Differential activation of the immune system by virulent Streptococcus pneumoniae strains determines recovery or death of the host, Clinical and Experimental Immunology, 134, 1, 2003. Crossref

  236. Nishikubo K, Murata Y, Tamaki S, Sugama K, Imanaka-Yoshida K, Yuda N, Kai M, Takamura S, Sebald W, Adachi Y, Yasutomi Y, A single administration of interleukin-4 antagonistic mutant DNA inhibits allergic airway inflammation in a mouse model of asthma, Gene Therapy, 10, 26, 2003. Crossref

  237. Shanafelt Armen B., Forte Carla P., Kasper James J., Sanchez-Pescador Lisa, Wetzel Monte, Gundel Robert, Greve Jeffrey M., An immune cell-selective interleukin 4 agonist, Proceedings of the National Academy of Sciences, 95, 16, 1998. Crossref

  238. Guo Jia, Casolaro Vincenzo, Seto Edward, Yang Wen-Ming, Chang Cindy, Seminario Maria-Cristina, Keen Judith, Georas Steve N., Yin-Yang 1 Activates Interleukin-4 Gene Expression in T Cells, Journal of Biological Chemistry, 276, 52, 2001. Crossref

  239. Efron Philip A., Moldawer Lyle L., Cytokines and Wound Healing: The Role of Cytokine and Anticytokine Therapy in the Repair Response, The Journal of Burn Care & Rehabilitation, 25, 2, 2004. Crossref

  240. Atitey Komlan, Anchang Benedict, Mathematical Modeling of Proliferative Immune Response Initiated by Interactions Between Classical Antigen-Presenting Cells Under Joint Antagonistic IL-2 and IL-4 Signaling, Frontiers in Molecular Biosciences, 9, 2022. Crossref

  241. Kotru Sharda, Klimuntowski Martin, Ridha Hashim, Uddin Zakir, Askhar Ali A., Singh Gurmit, Howlader Matiar M.R., Electrochemical sensing: A prognostic tool in the fight against COVID-19, TrAC Trends in Analytical Chemistry, 136, 2021. Crossref

  242. Yang Xiao Yi, Wang Li Hua, Mihalic Kelly, Xiao Weihua, Chen Taosheng, Li Peng, Wahl Larry M., Farrar William L., Interleukin (IL)-4 Indirectly Suppresses IL-2 Production by Human T Lymphocytes via Peroxisome Proliferator-activated Receptor γ Activated by Macrophage-derived 12/15-Lipoxygenase Ligands, Journal of Biological Chemistry, 277, 6, 2002. Crossref

  243. Davis Gerald S., Pfeiffer Linda M., Hemenway David R., Expansion of Interferon- γ –Producing Lung Lymphocytes in Mouse Silicosis, American Journal of Respiratory Cell and Molecular Biology, 20, 4, 1999. Crossref

  244. Li Fei, Liu Xiang-ping, Li Ji-an, Han Zhen-liang, Liu Pei-pei, Wang Yuan-yuan, Song Long, Chen Zong-bo, Correlation of an interleukin-4 gene polymorphism with susceptibility to severe enterovirus 71 infection in Chinese children, Archives of Virology, 160, 4, 2015. Crossref

  245. Kotepui Kwuntida Uthaisar, Thirarattanasunthon Phiman, Rattaprasert Pongruj, Kotepui Manas, A systematic review and meta-analysis of blood interleukin-4 levels concerning malaria infection and severity, Malaria Journal, 21, 1, 2022. Crossref

  246. Brandt Eric, Woerly Gaëtane, Younes Amena Ben, Loiseau Sylvie, Capron Monique, IL‐4 production by human polymorphonuclear neutrophils, Journal of Leukocyte Biology, 68, 1, 2000. Crossref

  247. Cheng Lianying, Chen Jie, Rong Xiaofeng, Hu Weicheng, Mechanism of Emodin in the Treatment of Rheumatoid Arthritis, Evidence-Based Complementary and Alternative Medicine, 2022, 2022. Crossref

  248. Shinkai Akeo, Yoshisue Hajime, Koike Masamichi, Shoji Emi, Nakagawa Satoshi, Saito Akiko, Takeda Tsuyoshi, Imabeppu Susumu, Kato Yuzuru, Hanai Nobuo, Anazawa Hideharu, Kuga Tetsuro, Nishi Tatsunari, A Novel Human CC Chemokine, Eotaxin-3, Which Is Expressed in IL-4-Stimulated Vascular Endothelial Cells, Exhibits Potent Activity Toward Eosinophils, The Journal of Immunology, 163, 3, 1999. Crossref

  249. Bastien Yolande, Toledano Baruch J., Mehio Noha, Cameron Lisa, Lamoukhaid Bouchaib, Renzi Poalo, Hamid Qutayba, Mazer Bruce D., Detection of Functional Platelet-Activating Factor Receptors on Human Tonsillar B Lymphocytes, The Journal of Immunology, 162, 9, 1999. Crossref

将发表的论文

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain