图书馆订阅: Guest
免疫学评论综述™

每年出版 6 

ISSN 打印: 1040-8401

ISSN 在线: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Functions of Granulocyte-Macrophage Colony-Stimulating Factor

卷 25, 册 5, 2005, pp. 405-428
DOI: 10.1615/CritRevImmunol.v25.i5.50
Get accessGet access

摘要

GM-CSF was originally defined by its ability to generate in vitro granulocyte and macrophage colonies from bone marrow precursor cells. Apart from its physiological role in the control of alveolar macrophage development, it now appears more likely that its major role lies in its ability to govern the properties of the more mature myeloid cells of the granulocyte and macrophage lineages, particularly during host defence and inflammatory reactions. Recent evidence is summarized below for a key role for GM-CSF in inflammatory and autoimmune diseases, making it therefore worthy of consideration for targeting. Such evidence includes disease exacerbation following its administration and amelioration of disease in animal models by GM-CSF gene targeting or by anti-GM-CSF antibody blockade. This review summarizes the evidence supporting a major role for GM-CSF in inflammation and autoimmunity and its functions as major regulator governing granulocyte and macrophage lineage populations at all stages of maturation.

对本文的引用
  1. Hemachandra Reddy P., Manczak Maria, Zhao Wei, Nakamura Kazuhiro, Bebbington Christopher, Yarranton Geoffrey, Mao Peizhong, Granulocyte-macrophage colony-stimulating factor antibody suppresses microglial activity: implications for anti-inflammatory effects in Alzheimer’s Disease and multiple sclerosis, Journal of Neurochemistry, 111, 6, 2009. Crossref

  2. Conti Lucia, Cardone Marco, Varano Barbara, Puddu Patrizia, Belardelli Filippo, Gessani Sandra, Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes, European Journal of Immunology, 38, 3, 2008. Crossref

  3. Fu Jun, Sha Beverly E, Thomas Larry L, HIV-1–Infected Peripheral Blood Mononuclear Cells Enhance Neutrophil Survival and HLA-DR Expression Via Increased Production of GM-CSF: Implications for HIV-1 Infection, JAIDS Journal of Acquired Immune Deficiency Syndromes, 56, 1, 2011. Crossref

  4. Martinez-Moczygemba Margarita, Huston David P., Immune Dysregulation in the Pathogenesis of Pulmonary Alveolar Proteinosis, Current Allergy and Asthma Reports, 10, 5, 2010. Crossref

  5. Jinushi Masahisa, Nakazaki Yukoh, Dougan Michael, Carrasco Daniel R., Mihm Martin, Dranoff Glenn, MFG-E8–mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF, Journal of Clinical Investigation, 117, 7, 2007. Crossref

  6. Hamilton John A., Colony-stimulating factors in inflammation and autoimmunity, Nature Reviews Immunology, 8, 7, 2008. Crossref

  7. Nguyen Minh C., Tu Guang Huan, Koprivnikar Kathryn E., Gonzalez-Edick Melissa, Jooss Karin U., Harding Thomas C., Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy, Cancer Immunology, Immunotherapy, 59, 9, 2010. Crossref

  8. Lanfranconi S., Locatelli F., Corti S., Candelise L., Comi G. P., Baron P. L., Strazzer S., Bresolin N., Bersano A., Growth factors in ischemic stroke, Journal of Cellular and Molecular Medicine, 15, 8, 2011. Crossref

  9. Trapnell Bruce C, Carey Brenna C, Uchida Kanji, Suzuki Takuji, Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages, Current Opinion in Immunology, 21, 5, 2009. Crossref

  10. Dittel Bonnie N., CD4 T cells: Balancing the coming and going of autoimmune-mediated inflammation in the CNS, Brain, Behavior, and Immunity, 22, 4, 2008. Crossref

  11. Szeliga Jacek, Daniel D. Sundarsingh, Yang Ching-Hui, Sever-Chroneos Zvjezdana, Jagannath Chinnaswamy, Chroneos Zissis C., Granulocyte–macrophage colony stimulating factor-mediated innate responses in tuberculosis, Tuberculosis, 88, 1, 2008. Crossref

  12. Coomes Stephanie M., Hubbard Leah L. N., Moore Bethany B., Impaired pulmonary immunity post-bone marrow transplant, Immunologic Research, 50, 1, 2011. Crossref

  13. Amiri Sara, Ghazanfari Tooba, Yaraee Roya, Salimi Hassan, Ebtekar Massoumeh, Shams Jalaleddin, Ghasemi Hassan, Pourfarzam Shahryar, Moin Athar, Sharifnia Zarin, Soroush Mohammad R., Faghihzadeh Soghrat, Hassan Zuhair M., Serum levels of GM-CSF 20years after sulfur mustard exposure: Sardasht-Iran Cohort Study, International Immunopharmacology, 9, 13-14, 2009. Crossref

  14. Egea Laia, Hirata Yoshihiro, Kagnoff Martin F, GM-CSF: a role in immune and inflammatory reactions in the intestine, Expert Review of Gastroenterology & Hepatology, 4, 6, 2010. Crossref

  15. Cook Andrew D., Turner Amanda L., Braine Emma L., Pobjoy Jarrad, Lenzo Jason C., Hamilton John A., Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis, Arthritis & Rheumatism, 63, 8, 2011. Crossref

  16. Hercus Timothy R., Thomas Daniel, Guthridge Mark A., Ekert Paul G., King-Scott Jack, Parker Michael W., Lopez Angel F., The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease, Blood, 114, 7, 2009. Crossref

  17. Lederle Wiltrud, Depner Sofia, Schnur Sabine, Obermueller Eva, Catone Nicola, Just Alexandra, Fusenig Norbert E., Mueller Margareta M., IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines, International Journal of Cancer, 128, 12, 2011. Crossref

  18. Brochériou Isabelle, Maouche Seraya, Durand Hervé, Braunersreuther Vincent, Le Naour Gilles, Gratchev Alexei, Koskas Fabien, Mach François, Kzhyshkowska Julia, Ninio Ewa, Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: Implication in atherosclerosis, Atherosclerosis, 214, 2, 2011. Crossref

  19. Shi Xiaojun, Zhang Xinji, Li Jinlong, Guo Fangfang, Hu Zhiming, Jing Yuming, Bai Li, Chen Sansan, Wan Pei, Wang Fei, Gao Jimin, Tan Wanlong, Sequential administration of GM-CSF and IL-2 surface-modified MB49 cells vaccines against the metastatic bladder cancer, Urologic Oncology: Seminars and Original Investigations, 31, 6, 2013. Crossref

  20. Li H.X., Sze S.C.W., Tong Y., Ng T.B., Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes, Journal of Ethnopharmacology, 123, 2, 2009. Crossref

  21. Jeong Hyun-Ja, Shin Seung-Youp, Oh Hyun-A, Kim Min-Ho, Cho Joong-Saeng, Kim Hyung-Min, IL-32 up-regulation is associated with inflammatory cytokine production in allergic rhinitis, The Journal of Pathology, 224, 4, 2011. Crossref

  22. Puljic Ruzica, Benediktus Ewald, Plater-Zyberk Christine, Baeuerle Patrick A., Szelenyi Stefan, Brune Kay, Pahl Andreas, Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF, European Journal of Pharmacology, 557, 2-3, 2007. Crossref

  23. Conti Lucia, Gessani Sandra, GM-CSF in the generation of dendritic cells from human blood monocyte precursors: Recent advances, Immunobiology, 213, 9-10, 2008. Crossref

  24. Starnes Linda Marie, Sorrentino Antonio, Pelosi Elvira, Ballarino Monica, Morsilli Ornella, Biffoni Mauro, Santoro Simona, Felli Nadia, Castelli Germana, De Marchis Maria Laura, Mastroberardino Gianfranco, Gabbianelli Marco, Fatica Alessandro, Bozzoni Irene, Nervi Clara, Peschle Cesare, NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls β-globin and G-CSF receptor expression, Blood, 114, 9, 2009. Crossref

  25. Hansen Guido, Hercus Timothy R., McClure Barbara J., Stomski Frank C., Dottore Mara, Powell Jason, Ramshaw Hayley, Woodcock Joanna M., Xu Yibin, Guthridge Mark, McKinstry William J., Lopez Angel F., Parker Michael W., The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor Activation, Cell, 134, 3, 2008. Crossref

  26. Sheikh Nadeem A., Petrylak Daniel, Kantoff Philip W., dela Rosa Corazon, Stewart Frances P., Kuan Ling-Yu, Whitmore James B., Trager James B., Poehlein Christian H., Frohlich Mark W., Urdal David L., Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer, Cancer Immunology, Immunotherapy, 62, 1, 2013. Crossref

  27. Michelini Flavia M., Zorrilla Pilar, Robello Carlos, Alché Laura E., Immunomodulatory activity of an anti-HSV-1 synthetic stigmastane analog, Bioorganic & Medicinal Chemistry, 21, 2, 2013. Crossref

  28. Paquet Joseph, Goebel Jean-Christophe, Delaunay Camille, Pinzano Astrid, Grossin Laurent, Cournil-Henrionnet Christel, Gillet Pierre, Netter Patrick, Jouzeau Jean-Yves, Moulin David, Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?, Arthritis Research & Therapy, 14, 2, 2012. Crossref

  29. Hayashi Kozaburo, Hooper Laura C., Okuno Toshiomi, Takada Yuichiro, Hooks John J., Inhibition of HSV-1 by chemoattracted neutrophils: supernatants of corneal epithelial cells (HCE) and macrophages (THP-1) treated with virus components chemoattract neutrophils (PMN), and supernatants of PMN treated with these conditioned media inhibit viral growth, Archives of Virology, 157, 7, 2012. Crossref

  30. Broughton Sophie E., Dhagat Urmi, Hercus Timothy R., Nero Tracy L., Grimbaldeston Michele A., Bonder Claudine S., Lopez Angel F., Parker Michael W., The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling, Immunological Reviews, 250, 1, 2012. Crossref

  31. Mentor-Marcel Roycelynn A., Bobe Gerd, Sardo Christine, Wang Li-Shu, Kuo Chieh-Ti, Stoner Gary, Colburn Nancy H., Plasma Cytokines as Potential Response Indicators to Dietary Freeze-Dried Black Raspberries in Colorectal Cancer Patients, Nutrition and Cancer, 64, 6, 2012. Crossref

  32. Hercus Timothy R., Broughton Sophie E., Ekert Paul G., Ramshaw Hayley S., Perugini Michelle, Grimbaldeston Michele, Woodcock Joanna M., Thomas Daniel, Pitson Stuart, Hughes Timothy, D'Andrea Richard J., Parker Michael W., Lopez Angel F., The GM-CSF receptor family: Mechanism of activation and implications for disease, Growth Factors, 30, 2, 2012. Crossref

  33. Hayashi Kozaburo, Hooper Laura C., Shimomura Yoshikazu, Who Pays the Toll for Solving the Enigma of Corneal Herpes?, Cornea, 32, Supplement 1, 2013. Crossref

  34. Jain Preeti, Singh Rani, Saxena V.K., Singh K.B., Ahmed K.A., Tiwari A.K., Saxena M., Sundaresan N.R., In vitro rapid clearance of infectious bursal disease virus in peripheral blood mononuclear cells of chicken lines divergent for antibody response might be related to the enhanced expression of proinflammatory cytokines, Research in Veterinary Science, 95, 3, 2013. Crossref

  35. Rostami Abdolmohamad, Ciric Bogoljub, Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination, Journal of the Neurological Sciences, 333, 1-2, 2013. Crossref

  36. Zhang Hong-Liang, Zheng Xiang-Yu, Zhu Jie, Th1/Th2/Th17/Treg cytokines in Guillain–Barré syndrome and experimental autoimmune neuritis, Cytokine & Growth Factor Reviews, 24, 5, 2013. Crossref

  37. Bedoya Simone Kennedy, Lam Brandon, Lau Kenneth, Larkin Joseph, Th17 Cells in Immunity and Autoimmunity, Clinical and Developmental Immunology, 2013, 2013. Crossref

  38. Hercus Timothy R., Dhagat Urmi, Kan Winnie L.T., Broughton Sophie E., Nero Tracy L., Perugini Michelle, Sandow Jarrod J., D’Andrea Richard J., Ekert Paul G., Hughes Timothy, Parker Michael W., Lopez Angel F., Signalling by the βc family of cytokines, Cytokine & Growth Factor Reviews, 24, 3, 2013. Crossref

  39. van Nieuwenhuijze Annemarie, Koenders Marije, Roeleveld Debbie, Sleeman Matthew A., van den Berg Wim, Wicks Ian P., GM-CSF as a therapeutic target in inflammatory diseases, Molecular Immunology, 56, 4, 2013. Crossref

  40. Bilgici Birsen, Ecemis Gulcin C., Tuncel Ozgur K., Bayrak Ilkay K., Kan Elif K., Atmaca Aysegul, VEGF and GM-CSF levels in nodular thyroid diseases, Endocrine, 45, 1, 2014. Crossref

  41. Brennan Frank R., MAbs Targeting Soluble Mediators in Phase 1 and 2 Clinical Studies Immunological Disorders, in Handbook of Therapeutic Antibodies, 2014. Crossref

  42. Chalouhi Nohra, Theofanis Thana, Starke Robert M., Zanaty Mario, Jabbour Pascal, Dooley Sarah A., Hasan David, Potential Role of Granulocyte–Monocyte Colony-Stimulating Factor in the Progression of Intracranial Aneurysms, DNA and Cell Biology, 34, 1, 2015. Crossref

  43. Zhu Yong-tong, Zhao Zhen, Fu Xin-yang, Luo Yang, Lei Cheng-yong, Chen Wei, Li Fei, Pang Shi-yu, Chen San-san, Tan Wan-long, The granulocyte macrophage–colony stimulating factor surface modified MB49 bladder cancer stem cells vaccine against metastatic bladder cancer, Stem Cell Research, 13, 1, 2014. Crossref

  44. Aliper Alexander M., Frieden‐Korovkina Victoria P., Buzdin Anton, Roumiantsev Sergey A., Zhavoronkov Alex, A role for G‐CSF and GM‐CSF in nonmyeloid cancers, Cancer Medicine, 3, 4, 2014. Crossref

  45. NAKAGAKI Kazuhide, NUNOMURA Yuka, UCHIDA Kanji, NAKATA Koh, TAZAWA Ryushi, Up-Regulation of Cluster of Differentiation (CD) 11b Expression on the Surface of Canine Granulocytes with Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Journal of Veterinary Medical Science, 76, 8, 2014. Crossref

  46. Ashhurst Thomas Myles, Vreden Caryn van, Niewold Paula, King Nicholas Jonathan Cole, The plasticity of inflammatory monocyte responses to the inflamed central nervous system, Cellular Immunology, 291, 1-2, 2014. Crossref

  47. Colin Sophie, Chinetti-Gbaguidi Giulia, Staels Bart, Macrophage phenotypes in atherosclerosis, Immunological Reviews, 262, 1, 2014. Crossref

  48. Kumar Prabhakaran, Subramaniyam Ganesan, Molecular underpinnings of Th17 immune-regulation and their implications in autoimmune diabetes, Cytokine, 71, 2, 2015. Crossref

  49. Aumailley Lucie, Dubois Marie Julie, Garand Chantal, Marette André, Lebel Michel, Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase, Experimental Gerontology, 72, 2015. Crossref

  50. Avci A. Berkant, Feist Eugen, Burmester Gerd-R., A Promising Target in Rheumatoid Arthritis Treatment: Granulocyte-Macrophage Colony-Stimulating Factor, Current Treatment Options in Rheumatology, 1, 4, 2015. Crossref

  51. Dorovini-Zis Katerina, Easton Alexander, Inflammatory Mediators and the Blood-Brain Barrier, in The Blood-Brain Barrier in Health and Disease, Volume One, 2015. Crossref

  52. Bhattacharya Palash, Budnick Isadore, Singh Medha, Thiruppathi Muthusamy, Alharshawi Khaled, Elshabrawy Hatem, Holterman Mark J., Prabhakar Bellur S., Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy, Journal of Interferon & Cytokine Research, 35, 8, 2015. Crossref

  53. Shiomi Aoi, Usui Takashi, Pivotal Roles of GM-CSF in Autoimmunity and Inflammation, Mediators of Inflammation, 2015, 2015. Crossref

  54. Mathias Brittany, Szpila Benjamin E., Moore Frederick A., Efron Philip A., Moldawer Lyle L., A Review of GM-CSF Therapy in Sepsis, Medicine, 94, 50, 2015. Crossref

  55. Ciric Bogoljub, Rasouli Javad, Rostami Abdolmohamad, Granulocyte-Macrophage Colony-Stimulating Factor in Central Nervous System Autoimmunity, in Multiple Sclerosis, 2016. Crossref

  56. Hamilton John A, GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential, Expert Review of Clinical Immunology, 11, 4, 2015. Crossref

  57. Maksaereekul Saipiroon, Dubie Robert A., Shen Xiaoying, Kieu Hung, Dean Gregg A., Sparger Ellen E., Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-α plasmids preserves global CD4 T lymphocyte function after challenge with FIV, Vaccine, 27, 28, 2009. Crossref

  58. Spengler Mark, Adler Michael, Niemeyer Christof M., Highly sensitive ligand-binding assays in pre-clinical and clinical applications: immuno-PCR and other emerging techniques, The Analyst, 140, 18, 2015. Crossref

  59. Ramaglia Luca, Di Spigna Gaetano, Capece Gabriele, Sbordone Carolina, Salzano Salvatore, Postiglione Loredana, Differentiation, apoptosis, and GM-CSF receptor expression of human gingival fibroblasts on a titanium surface treated by a dual acid-etched procedure, Clinical Oral Investigations, 19, 9, 2015. Crossref

  60. Kostic Milos, Stojanovic Ivana, Marjanovic Goran, Zivkovic Nikola, Cvetanovic Ana, Deleterious versus protective autoimmunity in multiple sclerosis, Cellular Immunology, 296, 2, 2015. Crossref

  61. Scaldaferri Franco, Vetrano Stefania, Mesenchymal Stem Cells in IBD: unMaSCing Their Therapeutic Mechanisms, Digestive Diseases and Sciences, 60, 7, 2015. Crossref

  62. Vogel Daphne Y. S., Kooij Gijs, Heijnen Priscilla D. A. M., Breur Marjolein, Peferoen Laura A. N., van der Valk Paul, de Vries Helga E., Amor Sandra, Dijkstra Christine D., GM-CSF promotes migration of human monocytes across the blood brain barrier, European Journal of Immunology, 45, 6, 2015. Crossref

  63. Na Yi Rang, Gu Gyo Jung, Jung Daun, Kim Young Won, Na Juri, Woo Jin Sun, Cho Joo Youn, Youn Hyewon, Seok Seung Hyeok, GM-CSF Induces Inflammatory Macrophages by Regulating Glycolysis and Lipid Metabolism, The Journal of Immunology, 197, 10, 2016. Crossref

  64. Chen Gwo-Hsiao, Teitz-Tennenbaum Seagal, Neal Lori M., Murdock Benjamin J., Malachowski Antoni N., Dils Anthony J., Olszewski Michal A., Osterholzer John J., Local GM-CSF–Dependent Differentiation and Activation of Pulmonary Dendritic Cells and Macrophages Protect against Progressive Cryptococcal Lung Infection in Mice, The Journal of Immunology, 196, 4, 2016. Crossref

  65. Rajagopalan Govindarajan, Mangalam Ashutosh K., Sen Moon M., Cheng Shen, Kudva Yogish C., David Chella S., Autoimmunity in HLA-DQ8 transgenic mice expressing granulocyte/macrophage-colony stimulating factor in the beta cells of islets of langerhans, Autoimmunity, 40, 3, 2007. Crossref

  66. Sadeghi Kambis, Wisgrill Lukas, Wessely Isabelle, Diesner Susanne C., Schüller Simone, Dürr Celia, Heinle Armando, Sachet Monika, Pollak Arnold, Förster-Waldl Elisabeth, Spittler Andreas, Zamboni Dario S., GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes, PLOS ONE, 11, 10, 2016. Crossref

  67. Bonomo Adriana, Monteiro Ana Carolina, Gonçalves-Silva Triciana, Cordeiro-Spinetti Eric, Galvani Rômulo Gonçalves, Balduino Alex, A T Cell View of the Bone Marrow, Frontiers in Immunology, 7, 2016. Crossref

  68. Papp Stefanie, Moderzynski Kristin, Rauch Jessica, Heine Liza, Kuehl Svenja, Richardt Ulricke, Mueller Heidelinde, Fleischer Bernhard, Osterloh Anke, Makepeace Benjamin L, Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells, PLOS Neglected Tropical Diseases, 10, 8, 2016. Crossref

  69. Kasahara Shinji, Jhingran Anupam, Dhingra Sourabh, Salem Anand, Cramer Robert A., Hohl Tobias M., Role of Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Regulating Neutrophil Antifungal Activity and the Oxidative Burst During Respiratory Fungal Challenge, Journal of Infectious Diseases, 213, 8, 2016. Crossref

  70. Katz Sándor, Zsiros Viktória, Dóczi Nikolett, Szabó Arnold, Biczó Ádám, Kiss Anna L., GM-CSF and GM-CSF receptor have regulatory role in transforming rat mesenteric mesothelial cells into macrophage-like cells, Inflammation Research, 65, 10, 2016. Crossref

  71. Li Zhanzhan, Mao Ruoyu, Teng Da, Hao Ya, Chen Huixian, Wang Xiumin, Wang Xiao, Yang Na, Wang Jianhua, Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus, Scientific Reports, 7, 1, 2017. Crossref

  72. Gieryng Anna, Pszczolkowska Dominika, Walentynowicz Kacper A, Rajan Wenson D, Kaminska Bozena, Immune microenvironment of gliomas, Laboratory Investigation, 97, 5, 2017. Crossref

  73. Dey Raja, Ji Kunmei, Liu Zhigang, Chen Lin, Xu Wenqing, A Cytokine–Cytokine Interaction in the Assembly of Higher-Order Structure and Activation of the Interleukine-3:Receptor Complex, PLoS ONE, 4, 4, 2009. Crossref

  74. Ifergan Igal, Davidson Todd S., Kebir Hania, Xu Dan, Palacios-Macapagal Daphne, Cann Jennifer, Rodgers Jane M., Hunter Zoe N., Pittet Camille L., Beddow Sara, Jones Clare A., Prat Alexandre, Sleeman Matthew A., Miller Stephen D., Targeting the GM-CSF receptor for the treatment of CNS autoimmunity, Journal of Autoimmunity, 84, 2017. Crossref

  75. Chen Yaqiong, Zhao Zhi, Chen Yu, Lv Zhonglin, Ding Xin, Wang Renxi, Xiao He, Hou Chunmei, Shen Beifen, Feng Jiannan, Guo Renfeng, Li Yan, Peng Hui, Han Gencheng, Chen Guojiang, An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer, Scientific Reports, 7, 1, 2017. Crossref

  76. Kiku Yoshio, Ozawa Tomomi, Takahashi Hideyuki, Kushibiki Shiro, Inumaru Shigeki, Shingu Hiroyuki, Nagasawa Yuya, Watanabe Atsushi, Hata Eiji, Hayashi Tomohito, Effect of intramammary infusion of recombinant bovine GM-CSF and IL-8 on CMT score, somatic cell count, and milk mononuclear cell populations in Holstein cows with Staphylococcus aureus subclinical mastitis, Veterinary Research Communications, 41, 3, 2017. Crossref

  77. Noack Mélissa, Miossec Pierre, Selected cytokine pathways in rheumatoid arthritis, Seminars in Immunopathology, 39, 4, 2017. Crossref

  78. Burkhardt Jana, Kirsten Holger, Wolfram Grit, Quente Elfi, Ahnert Peter, Differential allelic expression of IL13 and CSF2 genes associated with asthma, Genetics and Molecular Biology, 35, 3, 2012. Crossref

  79. Cheung Tommy Tsang, McInnes Iain B., Future therapeutic targets in rheumatoid arthritis?, Seminars in Immunopathology, 39, 4, 2017. Crossref

  80. Ballinger Megan N., Hubbard Leah L. N., McMillan Tracy R., Toews Galen B., Peters-Golden Marc, Paine Robert, Moore Bethany B., Paradoxical role of alveolar macrophage-derived granulocyte-macrophage colony-stimulating factor in pulmonary host defense post-bone marrow transplantation, American Journal of Physiology-Lung Cellular and Molecular Physiology, 295, 1, 2008. Crossref

  81. Prell R.A., Tarrant J.M., Cytokines: Role in Homeostasis and Disease States, in Comprehensive Toxicology, 2018. Crossref

  82. Tahmasebinia Foozhan, Pourgholaminejad Arash, The role of Th17 cells in auto-inflammatory neurological disorders, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 79, 2017. Crossref

  83. Thatcher Thomas H., Benson Randi P., Phipps Richard P., Sime Patricia J., High-dose but not low-dose mainstream cigarette smoke suppresses allergic airway inflammation by inhibiting T cell function, American Journal of Physiology-Lung Cellular and Molecular Physiology, 295, 3, 2008. Crossref

  84. Sharma Mahima, Dash Pujarini, Sahoo Pramod K., Dixit Aparna, Th2-biased immune response and agglutinating antibodies generation by a chimeric protein comprising OmpC epitope (323–336) of Aeromonas hydrophila and LTB, Immunologic Research, 66, 1, 2018. Crossref

  85. Na Yi Rang, Hong Ji Hye, Lee Min Yong, Jung Jae Hun, Jung Daun, Kim Young Won, Son Dain, Choi Murim, Kim Kwang Pyo, Seok Seung Hyeok, Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF) Grown Macrophages Derived from Murine Bone Marrow Cells*, Molecular & Cellular Proteomics, 14, 10, 2015. Crossref

  86. Armani Chiara, Catalani Elisabetta, Balbarini Alberto, Bagnoli Paola, Cervia Davide, Expression, pharmacology, and functional role of somatostatin receptor subtypes 1 and 2 in human macrophages, Journal of Leukocyte Biology, 81, 3, 2007. Crossref

  87. Huizinga T. W. J., Batalov A., Stoilov R., Lloyd E., Wagner T., Saurigny D., Souberbielle B., Esfandiari E., Phase 1b randomized, double-blind study of namilumab, an anti-granulocyte macrophage colony-stimulating factor monoclonal antibody, in mild-to-moderate rheumatoid arthritis, Arthritis Research & Therapy, 19, 1, 2017. Crossref

  88. Meshkibaf Shahab, William Gower Mark, Dekaban Gregory A., Ouk Kim Sung, G-CSF preferentially supports the generation of gut-homing Gr-1highmacrophages in M-CSF-treated bone marrow cells, Journal of Leukocyte Biology, 96, 4, 2014. Crossref

  89. Nicol Louise S.C., Thornton Peter, Hatcher Jon P., Glover Colin P., Webster Carl I., Burrell Matthew, Hammett Kessia, Jones Clare A., Sleeman Matthew A., Billinton Andrew, Chessell Iain, Central inhibition of granulocyte-macrophage colony-stimulating factor is analgesic in experimental neuropathic pain, Pain, 159, 3, 2018. Crossref

  90. Yu Shuangjiang, He Chaoliang, Chen Xuesi, Injectable Hydrogels as Unique Platforms for Local Chemotherapeutics-Based Combination Antitumor Therapy, Macromolecular Bioscience, 18, 12, 2018. Crossref

  91. Fleetwood Andrew J., Dinh Hang, Cook Andrew D., Hertzog Paul J, Hamilton John A., GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling, Journal of Leukocyte Biology, 86, 2, 2009. Crossref

  92. Chakrabarti Subhadeep, Chan Carmen K., Jiang Yanyan, Davidge Sandra T., Neuronal nitric oxide synthase regulates endothelial inflammation, Journal of Leukocyte Biology, 91, 6, 2012. Crossref

  93. Furuya Makiko Yashiro, Asano Tomoyuki, Sumichika Yuya, Sato Shuzo, Kobayashi Hiroko, Watanabe Hiroshi, Suzuki Eiji, Kozuru Hideko, Yatsuhashi Hiroshi, Koga Tomohiro, Ohira Hiromasa, Sekine Hideharu, Kawakami Atsushi, Migita Kiyoshi, Tofacitinib inhibits granulocyte–macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils, Arthritis Research & Therapy, 20, 1, 2018. Crossref

  94. Dhagat Urmi, Hercus Timothy R., Broughton Sophie E., Nero Tracy L., Cheung Tung Shing Karen S., Barry Emma F., Thomson Christy A., Bryson Steve, Pai Emil F., McClure Barbara J., Schrader John W., Lopez Angel F., Parker Michael W., The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities, mAbs, 2018. Crossref

  95. Burmester Gerd R., McInnes Iain B., Kremer Joel M., Miranda Pedro, Vencovský Jiří, Godwood Alex, Albulescu Marius, Michaels M. Alex, Guo Xiang, Close David, Weinblatt Michael, Mavrilimumab, a Fully Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Monoclonal Antibody, Arthritis & Rheumatology, 70, 5, 2018. Crossref

  96. Halstead E. Scott, Umstead Todd M., Davies Michael L., Kawasawa Yuka Imamura, Silveyra Patricia, Howyrlak Judie, Yang Linlin, Guo Weichao, Hu Sanmei, Hewage Eranda Kurundu, Chroneos Zissis C., GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization, Respiratory Research, 19, 1, 2018. Crossref

  97. Wu Un-In, Olivier Kenneth N, Kuhns Douglas B, Fink Danielle L, Sampaio Elizabeth P, Zelazny Adrian M, Shallom Shamira J, Marciano Beatriz E, Lionakis Michail S, Holland Steven M, Patients with Idiopathic Pulmonary Nontuberculous Mycobacterial Disease Have Normal Th1/Th2 Cytokine Responses but Diminished Th17 Cytokine and Enhanced Granulocyte-Macrophage Colony-Stimulating Factor Production, Open Forum Infectious Diseases, 6, 12, 2019. Crossref

  98. Lacey Derek C., Achuthan Adrian, Fleetwood Andrew J., Dinh Hang, Roiniotis John, Scholz Glen M., Chang Melody W., Beckman Sandra K., Cook Andrew D., Hamilton John A., Defining GM-CSF– and Macrophage-CSF–Dependent Macrophage Responses by In Vitro Models, The Journal of Immunology, 188, 11, 2012. Crossref

  99. Nagaratnam Nages, Nagaratnam Kujan, Cheuk Gary, Blood Disorders in the Elderly, in Diseases in the Elderly, 2016. Crossref

  100. Pazdrak Konrad, Young Travis W., Straub Christof, Stafford Susan, Kurosky Alexander, Priming of Eosinophils by GM-CSF Is Mediated by Protein Kinase CβII-Phosphorylated L-Plastin, The Journal of Immunology, 186, 11, 2011. Crossref

  101. Ponomarev Eugene D., Shriver Leah P., Maresz Katarzyna, Pedras-Vasconcelos Joao, Verthelyi Daniela, Dittel Bonnie N., GM-CSF Production by Autoreactive T Cells Is Required for the Activation of Microglial Cells and the Onset of Experimental Autoimmune Encephalomyelitis, The Journal of Immunology, 178, 1, 2007. Crossref

  102. Young Andrew, Linehan Eimear, Hams Emily, O’Hara Hall Aisling C., McClurg Angela, Johnston James A., Hunter Christopher A., Fallon Padraic G., Fitzgerald Denise C., Cutting Edge: Suppression of GM-CSF Expression in Murine and Human T Cells by IL-27, The Journal of Immunology, 189, 5, 2012. Crossref

  103. Hamilton John A., GM-CSF in inflammation, Journal of Experimental Medicine, 217, 1, 2020. Crossref

  104. Conigliaro Paola, Triggianese Paola, De Martino Erica, Fonti Giulia Lavinia, Chimenti Maria Sole, Sunzini Flavia, Viola Alessandra, Canofari Claudia, Perricone Roberto, Challenges in the treatment of Rheumatoid Arthritis, Autoimmunity Reviews, 18, 7, 2019. Crossref

  105. Fleetwood Andrew J., Lawrence Toby, Hamilton John A., Cook Andrew D., Granulocyte-Macrophage Colony-Stimulating Factor (CSF) and Macrophage CSF-Dependent Macrophage Phenotypes Display Differences in Cytokine Profiles and Transcription Factor Activities: Implications for CSF Blockade in Inflammation, The Journal of Immunology, 178, 8, 2007. Crossref

  106. Starosta Vitaliy, Pazdrak Konrad, Boldogh Istvan, Svider Tetyana, Kurosky Alexander, Lipoxin A4Counterregulates GM-CSF Signaling in Eosinophilic Granulocytes, The Journal of Immunology, 181, 12, 2008. Crossref

  107. Egea Laia, McAllister Christopher S., Lakhdari Omar, Minev Ivelina, Shenouda Steve, Kagnoff Martin F., GM-CSF Produced by Nonhematopoietic Cells Is Required for Early Epithelial Cell Proliferation and Repair of Injured Colonic Mucosa, The Journal of Immunology, 190, 4, 2013. Crossref

  108. Tekkesin Nilgun, Tetik Sermin, Therapeutic vaccines for pancreatic cancer, in Theranostic Approach for Pancreatic Cancer, 2019. Crossref

  109. Li Zhi, Lu Gen, Meng Guangxun, Pathogenic Fungal Infection in the Lung, Frontiers in Immunology, 10, 2019. Crossref

  110. Taylor Peter C., Saurigny Didier, Vencovsky Jiri, Takeuchi Tsutomu, Nakamura Tadashi, Matsievskaia Galina, Hunt Barbara, Wagner Thomas, Souberbielle Bernard, Efficacy and safety of namilumab, a human monoclonal antibody against granulocyte-macrophage colony-stimulating factor (GM-CSF) ligand in patients with rheumatoid arthritis (RA) with either an inadequate response to background methotrexate therapy or an inadequate response or intolerance to an anti-TNF (tumour necrosis factor) biologic therapy: a randomized, controlled trial, Arthritis Research & Therapy, 21, 1, 2019. Crossref

  111. Crotti Chiara, Agape Elena, Becciolini Andrea, Biggioggero Martina, Favalli Ennio Giulio, Targeting Granulocyte-Monocyte Colony-Stimulating Factor Signaling in Rheumatoid Arthritis: Future Prospects, Drugs, 79, 16, 2019. Crossref

  112. A. Hamilton John, Colony stimulating factors and macrophage heterogeneity, Inflammation and Regeneration, 31, 3, 2011. Crossref

  113. Layhadi Janice A., Fountain Samuel J., ATP-Evoked Intracellular Ca2+ Responses in M-CSF Differentiated Human Monocyte-Derived Macrophage are Mediated by P2X4 and P2Y11 Receptor Activation, International Journal of Molecular Sciences, 20, 20, 2019. Crossref

  114. El-Behi Mohamed, Ciric Bogoljub, Rostami Abdolmohamad, GM-CSF in Autoimmune Inflammation of the Central Nervous System, in Multiple Sclerosis Immunology, 2013. Crossref

  115. Sereno María, Gutiérrez-Gutiérrez Gerardo, Sandoval Carmen, Falagan Sandra, Jimenez-Gordo Ana María, Merino María, López-Menchaca Ramiro, Martínez-Martin Patricia, Roa Silvia, Casado Enrique, A favorable outcome of pneumonia COVID 19 in an advanced lung cancer patient with severe neutropenia: Is immunosuppression a risk factor for SARS-COV2 infection?, Lung Cancer, 145, 2020. Crossref

  116. Lee Kevin M.-C., Jarnicki Andrew, Achuthan Adrian, Fleetwood Andrew J., Anderson Gary P., Ellson Christian, Feeney Maria, Modis Louise K., Smith Julia E., Hamilton John A., Cook Andrew, CCL17 in Inflammation and Pain, The Journal of Immunology, 205, 1, 2020. Crossref

  117. Chaurasiya Shyambabu, Fong Yuman, Warner Susanne G., Optimizing Oncolytic Viral Design to Enhance Antitumor Efficacy: Progress and Challenges, Cancers, 12, 6, 2020. Crossref

  118. Li Xiaofeng, Wang Jiapo, Wu Weimin, Gao Hao, Liu Na, Zhan Guangxi, Li Li, Han Lingfei, Guo Xiaoqing, Myeloid‐derived suppressor cells promote epithelial ovarian cancer cell stemness by inducing the CSF2/p‐STAT3 signalling pathway, The FEBS Journal, 287, 23, 2020. Crossref

  119. Ifergan Igal, Miller Stephen D., Potential for Targeting Myeloid Cells in Controlling CNS Inflammation, Frontiers in Immunology, 11, 2020. Crossref

  120. Shang Lu, Li Jiawei, Song Chunsheng, Nina Zaytseva, Li Qiuke, Chou Shuli, Wang Zhihua, Shan Anshan, Hybrid Antimicrobial Peptide Targeting Staphylococcus aureus and Displaying Anti-infective Activity in a Murine Model, Frontiers in Microbiology, 11, 2020. Crossref

  121. Hollen McKenzie K., Efron Philip A., Mohr Alicia M., Is there a role for granulocyte-macrophage colony-stimulating factor and/or erythropoietin in critical illness?, in Evidence-Based Practice of Critical Care, 2020. Crossref

  122. Menzel Alain, Samouda Hanen, Dohet Francois, Loap Suva, Ellulu Mohammed S., Bohn Torsten, Common and Novel Markers for Measuring Inflammation and Oxidative Stress Ex Vivo in Research and Clinical Practice—Which to Use Regarding Disease Outcomes?, Antioxidants, 10, 3, 2021. Crossref

  123. Barbeck Mike, Schröder Marie-Luise, Alkildani Said, Jung Ole, Unger Ronald E., Exploring the Biomaterial-Induced Secretome: Physical Bone Substitute Characteristics Influence the Cytokine Expression of Macrophages, International Journal of Molecular Sciences, 22, 9, 2021. Crossref

  124. Pykhtina Mariya, Miroshnichenko Svetlana, Romanov Vladimir, Grazhdantseva Antonina, Kochneva Galina, Beklemishev Anatoly, Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity, Pharmaceuticals, 14, 5, 2021. Crossref

  125. Clayton Nicholas P., Khan-Malek Richard C., Dangler Charles A., Zhang Donghui, Ascah Alexis, Gains Malcolm, Gardner Brent, Mockbee Colleen, Keutzer Joan M., McManus John, Authier Simon, Sargramostim (rhu GM-CSF) Improves Survival of Non-Human Primates with Severe Bone Marrow Suppression after Acute, High-Dose, Whole-Body Irradiation, Radiation Research, 195, 2, 2020. Crossref

  126. Zhu Yong-tong, Pang Shi-yu, Lei Cheng-yong, Luo Yang, Chu Qing-jun, Tan Wan-long, Development of a therapy against metastatic bladder cancer using an interleukin-2 surface-modified MB49 bladder cancer stem cells vaccine, Stem Cell Research & Therapy, 6, 1, 2015. Crossref

  127. Wang Huan, Jin Ping, Sabatino Marianna, Ren Jiaqiang, Civini Sara, Bogin Vladimir, Ichim Thomas E, Stroncek David F, Comparison of endometrial regenerative cells and bone marrow stromal cells, Journal of Translational Medicine, 10, 1, 2012. Crossref

  128. Li Yankun, Gerbod-Giannone Marie-Christine, Seitz Heather, Cui Dongying, Thorp Edward, Tall Alan R., Matsushima Glenn K., Tabas Ira, Cholesterol-induced Apoptotic Macrophages Elicit an Inflammatory Response in Phagocytes, Which Is Partially Attenuated by the Mer Receptor, Journal of Biological Chemistry, 281, 10, 2006. Crossref

  129. Achuthan Adrian A., Lee Kevin M.C., Hamilton John A., Targeting GM-CSF in inflammatory and autoimmune disorders, Seminars in Immunology, 54, 2021. Crossref

  130. Luque‐Martin Rosario, Mander Palwinder K., Leenen Pieter J. M., Winther Menno P. J., Classic and new mediators for in vitro modelling of human macrophages , Journal of Leukocyte Biology, 109, 3, 2021. Crossref

  131. Chu Sherman, McCormick Thomas S., Lazarus Hillard M., Leal Luis O., Ghannoum Mahmoud A., Invasive fungal disease and the immunocompromised host including allogeneic hematopoietic cell transplant recipients: Improved understanding and new strategic approach with sargramostim, Clinical Immunology, 228, 2021. Crossref

  132. Hammami Ines, Chen Jingkui, Murschel Frederic, Bronte Vincenzo, De Crescenzo Gregory, Jolicoeur Mario, Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models, BMC Cell Biology, 13, 1, 2012. Crossref

  133. Lazarus Hillard M., Ragsdale Carolyn E., Gale Robert Peter, Lyman Gary H., Sargramostim (rhu GM-CSF) as Cancer Therapy (Systematic Review) and An Immunomodulator. A Drug Before Its Time?, Frontiers in Immunology, 12, 2021. Crossref

  134. Malengier-Devlies Bert, Metzemaekers Mieke, Wouters Carine, Proost Paul, Matthys Patrick, Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of Systemic Juvenile Idiopathic Arthritis, Frontiers in Immunology, 12, 2021. Crossref

  135. Simmons Andrew D., Li Betty, Gonzalez-Edick Melissa, Lin Carol, Moskalenko Marina, Du Thomas, Creson Jennifer, VanRoey Melinda J., Jooss Karin, GM-CSF-secreting cancer immunotherapies: preclinical analysis of the mechanism of action, Cancer Immunology, Immunotherapy, 56, 10, 2007. Crossref

  136. Sorrentino Antonio, Ferracin Manuela, Castelli Germana, Biffoni Mauro, Tomaselli Giada, Baiocchi Marta, Fatica Alessandro, Negrini Massimo, Peschle Cesare, Valtieri Mauro, Isolation and characterization of CD146+ multipotent mesenchymal stromal cells, Experimental Hematology, 36, 8, 2008. Crossref

  137. Reyes Leticia, Reinhard Mary, O'Donell L. J., Stevens Janet, Brown Mary B., Rat Strains Differ in Susceptibility to Ureaplasma parvum -Induced Urinary Tract Infection and Struvite Stone Formation , Infection and Immunity, 74, 12, 2006. Crossref

  138. Engels Eric A., Wu Xifeng, Gu Jian, Dong Qiong, Liu Jun, Spitz Margaret R., Systematic Evaluation of Genetic Variants in the Inflammation Pathway and Risk of Lung Cancer, Cancer Research, 67, 13, 2007. Crossref

  139. Jolly Amber Leah, Rau Sameeha, Chadha Anmol K., Abdulraheem Ekhlas Ahmed, Dean Deborah, Nacy Carol A., Stromal Fibroblasts Drive Host Inflammatory Responses That Are Dependent on Chlamydia trachomatis Strain Type and Likely Influence Disease Outcomes, mBio, 10, 2, 2019. Crossref

  140. Karagiannidis Ioannis, Salataj Eralda, Said Abu Egal Erika, Beswick Ellen J., G-CSF in tumors: Aggressiveness, tumor microenvironment and immune cell regulation, Cytokine, 142, 2021. Crossref

  141. Aghaalikhani Nazi, Rashtchizadeh Nadereh, Shadpour Pejman, Allameh Abdolamir, Mahmoodi Marzieh, Cancer stem cells as a therapeutic target in bladder cancer, Journal of Cellular Physiology, 234, 4, 2019. Crossref

  142. Moeller Maria, Kershaw Michael H., Cameron Rachel, Westwood Jennifer A., Trapani Joseph A., Smyth Mark J., Darcy Phillip K., Sustained Antigen-Specific Antitumor Recall Response Mediated by Gene-Modified CD4+ T Helper-1 and CD8+ T Cells, Cancer Research, 67, 23, 2007. Crossref

  143. Yin Zhi-Qiang, Han Hua, Yan Xianchun, Zheng Qi-Jun, Research Progress on the Pathogenesis of Aortic Dissection, Current Problems in Cardiology, 2022. Crossref

  144. Vico Tania, Youssif Catrin, Zare Fathema, Comalada Mònica, Sebastian Carlos, Lloberas Jorge, Celada Antonio, GM-CSF Protects Macrophages from DNA Damage by Inducing Differentiation, Cells, 11, 6, 2022. Crossref

  145. Zarini Simona, Gijón Miguel A., Folco Giancarlo, Murphy Robert C., Effect of Arachidonic Acid Reacylation on Leukotriene Biosynthesis in Human Neutrophils Stimulated with Granulocyte-macrophage Colony-stimulating Factor and Formyl-methionyl-leucyl-phenylalanine, Journal of Biological Chemistry, 281, 15, 2006. Crossref

  146. Nicholson Andrew G., Rice Alexandra J., Interstitial lung diseases, in Spencer's Pathology of the Lung, 2013. Crossref

  147. Wang Yi, Han Gencheng, Wang Ke, Liu Guijun, Wang Renxi, Xiao He, Li Xinying, Hou Chunmei, Shen Beifen, Guo Renfeng, Li Yan, Chen Guojiang, Tumor-Derived GM-CSF Promotes Inflammatory Colon Carcinogenesis via Stimulating Epithelial Release of VEGF, Cancer Research, 74, 3, 2014. Crossref

  148. Du T, Shi G, Li Y M, Zhang J F, Tian H W, Wei Y Q, Deng H, Yu D C, Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colony-stimulating factor or anti-CTLA4 antibody for the treatment of cancers, Cancer Gene Therapy, 21, 8, 2014. Crossref

  149. Verescakova Hana, Ambrozova Gabriela, Kubala Lukas, Perecko Tomas, Koudelka Adolf, Vasicek Ondrej, Rudolph Tanja K., Klinke Anna, Woodcock Steven R., Freeman Bruce A., Pekarova Michaela, Nitro-oleic acid regulates growth factor-induced differentiation of bone marrow-derived macrophages, Free Radical Biology and Medicine, 104, 2017. Crossref

  150. McCarthy Cormac, Carey Brenna C., Trapnell Bruce C., Autoimmune Pulmonary Alveolar Proteinosis, American Journal of Respiratory and Critical Care Medicine, 205, 9, 2022. Crossref

  151. He Songbing, Wang Liang, Sun Kang, Zhang Yanyun, Li Dechun, Enhanced anti-tumor immunity ex vivo induced by GM-CSF gene transducted dendritic cell vaccine, The Chinese-German Journal of Clinical Oncology, 10, 3, 2011. Crossref

  152. Shah Pritha, Siddique Aqsa, Thakkar Ami, Gharat Sankalp, Godad Angel, Kale Pravin, Doshi Gaurav, An update on novel therapeutic intervention in Rheumatoid arthritis, International Immunopharmacology, 109, 2022. Crossref

  153. Seo Soo Hong, Han Hee Dong, Noh Kyung Hee, Kim Tae Woo, Son Sang Wook, Chitosan hydrogel containing GMCSF and a cancer drug exerts synergistic anti-tumor effects via the induction of CD8+ T cell-mediated anti-tumor immunity, Clinical & Experimental Metastasis, 26, 3, 2009. Crossref

  154. Saita Kosuke, Moriuchi Yuta, Iwagawa Toshiro, Aihara Makoto, Takai Yoshihiro, Uchida Kanji, Watanabe Sumiko, Roles of CSF2 as a modulator of inflammation during retinal degeneration, Cytokine, 158, 2022. Crossref

  155. Cheng Lianying, Chen Jie, Rong Xiaofeng, Hu Weicheng, Mechanism of Emodin in the Treatment of Rheumatoid Arthritis, Evidence-Based Complementary and Alternative Medicine, 2022, 2022. Crossref

将发表的论文

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain