每年出版 6 期
ISSN 打印: 0743-4863
ISSN 在线: 2162-660X
Indexed in
Atopic Dermatitis: Drug Delivery Approaches in Disease Management
摘要
In this review, we describe the very basic of atopic dermatitis (AD), the established management strategies, and the advances in drug delivery approaches for successful therapeutic outcomes. The multifactorial pathophysiology of AD has given rise to the clinician's paradigm of topical and systemic therapy and potential combinations. However, incomplete remission of skin disorders like AD is a major challenge to be overcome. Recurrence is thought to be due to genetic and immunological etiologies and shortcomings in drug delivery. This difficulty has sparked research in nanocarrier-based delivery approaches as well as molecular biology-inspired stratagems to deal with the immunological imbalance and to address insufficiencies of delivery propositions. In this review, we assess various novel drug delivery strategies in terms of their success and utility. We present a brief compilation and assessment of management modalities to sensitize the readers to therapeutic scenario in AD.
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Jeong Ji Heun, Back Seung Keun, An Jong Hun, Lee Nam‐Seob, Kim Do‐Kyung, Na Chun Soo, Jeong Young‐Gil, Han Seung Yun, Topical film prepared with Rhus verniciflua extract‐loaded pullulan hydrogel for atopic dermatitis treatment , Journal of Biomedical Materials Research Part B: Applied Biomaterials, 107, 7, 2019. Crossref
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