每年出版 18 期
ISSN 打印: 1064-2285
ISSN 在线: 2162-6561
Indexed in
THERMAL ANALYSIS AND EXPERIMENTS OF LASER−TISSUE INTERACTIONS: A REVIEW
摘要
Studying the interaction of ultrashort pulse lasers with biological tissues and the corresponding mathematical modeling of possible thermal damage is of fundamental importance to the understanding of laser-tissue interaction for advancing surgical application of lasers. The objective of this paper is to review the existing techniques for thermal analysis of laser-tissue interaction, focusing on temperature rise and plasma-mediated ablation. Different laser-tissue interaction mechanisms are discussed, and the existing techniques for characterization of extent of damage are presented. A novel approach of using a focused laser beam from an ultrashort pulse laser source to ablate the subcutaneous tumors with minimal thermal effects is introduced. The extent of laser-induced damage is studied by determining the space-time expression patterns of heat shock proteins.
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