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ISSN 打印: 1045-4403

ISSN 在线: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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Association between the Epithelial Cadherin − 160C/A Polymorphism and Colorectal Cancer Risk: Evidence from a Meta-Analysis

卷 27, 册 4, 2017, pp. 347-354
DOI: 10.1615/CritRevEukaryotGeneExpr.2017020525
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摘要

The aim of the present study was to assess the association between the epithelial cadherin (CDH1) –160C/A polymorphism and colorectal cancer (CRC) using a meta-analysis. A literature search of PubMed, Embase, and Web of Science databases was performed for relevant studies. Statistical analyses were carried out using Stata 12.0 to combine all of the relevant studies. Odds ratio (OR) with 95% confidence interval (CI) values were applied to evaluate the strength of the association. Eight studies with 7231 cases and 7080 controls were included. The meta-analysis results showed that the CDH1 –160C/A polymorphism was significantly associated with CRC risk (AA vs. CC: OR = 0.98, 95% CI = 0.71–1.36; CA vs. CC: OR = 0.92, 95% CI = 0.86–0.99; dominant model: OR = 1.01, 95% CI = 0.81–1.26; recessive model: OR = 0.91, 95% CI = 0.81–1.02). In the subgroup analysis based on ethnicity, significant association was found between the CDH1 –160C > A polymorphism and CRC risk in Caucasians. In conclusion, the CDH1 –160C/A polymorphism may be a susceptible predictor for the risk of CRC in Caucasians.

对本文的引用
  1. Li Wenhuan, Xiao Deshuang, Wu Huawen, Xu Lewei, The epithelial cadherin –160C/A polymorphism is associated with decreased risk of colorectal cancer: a case–control study, Clinical and Experimental Medicine, 20, 1, 2020. Crossref

  2. Winarko Winarko, Rahayu Pudji , Soeatmadji Djoko, Mintaroem Karyono , Differences in the Expression of β-Catenin Nucleus/Cytoplasm Ratio e-Cadherin and n-Cadherin and Correlation of β-Catenin Cytoplasm and Cadherin in Model of Duke D Stage Colorectal Cancer Cell Line, Open Access Macedonian Journal of Medical Sciences, 9, B, 2021. Crossref

  3. Ye Chun‐Cui, Wang Jun, E‐cadherin ( CDH1 ) gene –160C/A polymorphism and the risk of colorectal cancer: A meta‐analysis involving 17,291 subjects , The Journal of Gene Medicine, 23, 10, 2021. Crossref

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