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国际生理学与病理学期刊

每年出版 4 

ISSN 打印: 2155-014X

ISSN 在线: 2155-0158

SJR: 0.116

Effect of Streptozotocin-Induced Diabetes and Incomplete Global Cerebral Ischemia on Apoptosis in the Rat Thymus

卷 3, 册 3, 2012, pp. 243-251
DOI: 10.1615/IntJPhysPathophys.v3.i3.50
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摘要

The effect of incomplete global cerebral ischemia-reperfusion on the activity in pro-and anti-apoptotic processes in the thymocytes by the intensity of the p53 and Bcl-2 protein expression was investigated. It has been shown that in the cortical zone of the rat thymus with four-month diabetes mellitus, as well as in control rats and animals with diabetes mellitus after cerebral ischemia-reperfusion, anti-apoptotic processes dominated. In the medullary area of the gland in rats with diabetes, anti-apoptotic mechanisms either complicated or uncomplicated with cerebral ischemia-reperfusion also predominated, but to a lesser extent than in the cortical zone.

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