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The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Effects of Yellow Brain Culinary-Medicinal Mushroom, Tremella mesenterica Ritz.:Fr. (Higher Basidiomycetes), on Immune Function in Normal and Type 1 Diabetic Rats

卷 14, 册 5, 2012, pp. 447-457
DOI: 10.1615/IntJMedMushr.v14.i5.20
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摘要

Diabetes mellitus (DM) is characterized by systemic low-grade inflammation and altered immunity. The fruiting bodies (FB) of Tremella mesenterica have been demonstrated to have anti-hyperglycemic and immunomodulatory activities. It is unclear whether submerged culture yeast-like cells (CC) of T. mesenterica have the same immune effects as FB. Here, we compared the immune effects of T. mesenterica FB and CC on immunocyte function. Male Wistar rats were intravenously injected with saline (normal rats) or streptozotocin (50 mg/kg, DM rats) and orally treated with placebo, FB, or CC (1 g/kg/day) for 2 weeks. Peripheral blood leukocytes and splenocytes were collected. In normal rats, FB and CC ingestion significantly decreased T-suppressor leukocyte numbers and interferon (IFN)-γ production in leukocytes (p < 0.05). In addition, CC treatment significantly decreased mitogen-stimulated tumor necrosis factor (TNF)-α and interleukin (IL)-6 production in leukocytes as well as the numbers of total and B splenocytes. In DM rats, FB significantly alleviated the diabetes-induced decreases in plasma TNF-α levels, T-helper splenocyte numbers, and IL-6 production in T leukocytes, and CC significantly attenuated the decreases in plasma TNF-α, IFN-γ, and IL-6 levels, as well as the increase in IL-6 production in T splenocytes induced by diabetes. Moreover, CC significantly decreased the numbers of T-helper leukocytes and B splenocytes as well as the production of TNF-α by splenocytes and IL-4 by leukocytes in DM rats. In conclusion, our results suggest that T. mesenterica FB and CC may decrease peripheral cell-mediated immunity in normal rats. However, in diabetic rats, FB may increase peripheral cell-mediated immunity, and CC may decrease pro-inflammatory and Th1 cytokine production.

对本文的引用
  1. Hsu Tai-Hao, Lee Chien-Hsing, Lin Fang-Yi, Wasser Solomon P., Lo Hui-Chen, The Fruiting Bodies, Submerged Culture Biomass, and Acidic Polysaccharide Glucuronoxylomannan of Yellow Brain Mushroom Tremella mesenterica Modulate the Immunity of Peripheral Blood Leukocytes and Splenocytes in Rats with Impaired Glucose Tolerance, Journal of Traditional and Complementary Medicine, 4, 1, 2014. Crossref

  2. Chen Chung-Hwan, Kang Lin, Lo Hui-Chen, Hsu Tai-Hao, Lin Fang-Yi, Lin Yi-Shan, Wang Zai-Jie, Chen Shih-Tse, Shen Chwan-Li, Polysaccharides of Trametes versicolor Improve Bone Properties in Diabetic Rats, Journal of Agricultural and Food Chemistry, 63, 42, 2015. Crossref

  3. Panda Mrunmaya K., Paul Manish, Singdevsachan Sameer K., Tayung Kumananda, Das Swagat K., Thatoi Hrudayanath, Promising Anti-cancer Therapeutics From Mushrooms: Current Findings and Future Perceptions, Current Pharmaceutical Biotechnology, 22, 9, 2021. Crossref

  4. Radović Jelena, Leković Aleksandra, Tačić Ana, Dodevska Margarita, Stanojković Tatjana, Marinković Tijana, Jelić Čedomir, Kundakovic-Vasović Tatjana, Black Trumpet, <i>Craterellus cornucopioides</i> (L.) Pers.: Culinary Mushroom with Angiotensin Converting Enzyme Inhibitory and Cytotoxic Activity, Polish Journal of Food and Nutrition Sciences, 2022. Crossref

  5. Finimundy Tiane C., Abreu Rui M.V., Bonetto Natalia, Scariot Fernando J., Dillon Aldo J.P., Echeverrigaray Sergio, Barros Lillian, Ferreira Isabel C.F.R., Henriques João A.P., Roesch-Ely Mariana, Apoptosis induction by Pleurotus sajor-caju (Fr.) Singer extracts on colorectal cancer cell lines, Food and Chemical Toxicology, 112, 2018. Crossref

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