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The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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The Nature of Apoptosis of Human Breast Cancer Cells Induced by Three Species of Genus Ganoderma P. Karst. (Aphyllophoromycetideae) Crude Extracts

卷 10, 册 2, 2008, pp. 115-125
DOI: 10.1615/IntJMedMushr.v10.i2.20
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摘要

The cytotoxic effect of crude extracts of three Ganoderma species (G. lucidum, G. tropicum, and G. tsugae) was screened against the human estrogen-independent cell line, MDA-MB-435 using a microculture tetrazolium (MTT) assay. The crude extract obtained from the fruiting body of Ganoderma lucidum by hot water extraction procedures had IC50 values ranging from 140 to 350 μg mL−1. Acridine-orange/propidium iodine staining, electron microscopy, and transmission electron microscopy showed that the crude extract caused both apoptosis and necrosis. The G. lucidum mycelial crude extract was most effective, with an IC50 value of 148 μg mL−1.

对本文的引用
  1. Tong Chow-Chin, Choong Yew-Keong, Umar Nor-Aini-B, Noordin Mohamed-Mustapha, Mohamed Suhaila, Cytotoxic activity induced by crude extracts of Ganoderma lucidum (W. Curt.: Fr.) P. Karst. on mouse myeloma cancer cell-line, World Journal of Microbiology and Biotechnology, 25, 4, 2009. Crossref

  2. Li Ya, Li Sha, Meng Xiao, Gan Ren-You, Zhang Jiao-Jiao, Li Hua-Bin, Dietary Natural Products for Prevention and Treatment of Breast Cancer, Nutrients, 9, 7, 2017. Crossref

  3. Iqbal Javed, Abbasi Banzeer Ahsan, Batool Riffat, Mahmood Tariq, Ali Barkat, Khalil Ali Talha, Kanwal Sobia, Shah Sayed Afzal, Ahmad Riaz, Potential phytocompounds for developing breast cancer therapeutics: Nature’s healing touch, European Journal of Pharmacology, 827, 2018. Crossref

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