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ISSN 在线: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Immune-Stimulating Effects of Mycoleptodonoides aitchisonii (Agaricomycetes) Water Extract via TNF-α and IFN-γ

卷 19, 册 9, 2017, pp. 809-815
DOI: 10.1615/IntJMedMushrooms.2017024248
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摘要

Mycoleptodonoides aitchisonii has been used as culinary material in East Asia. We previously reported the antiasthmatic effect of M. aitchisonii; in this study we evaluated the mushroom's immune-stimulating effects. To analyze these effects, we conducted an in vitro study with splenocytes and an in vivo study with the Porsolt enforced swim test. In the in vitro study, the cell proliferation effect of the M. aitchisonii water extract (WT) was measured and the in vivo study depended on the dose of M. aitchisonii WT and the effect on swimming duration; several immune reaction–related factors were assessed, such as white blood cell count, differential cell count, the ratio of thymus or spleen weight to body weight, and concentrations of some cytokines in serum. Almost all measured factors that are related to immune stimulation were dose-dependently increased, such as the number of splenocytes and monocytes, the swimming duration, the relative weight of the thymus, and the expression of tumor necrosis factor (TNF)-α and interferon (IFN)-γ. Based on the results, we conclude that M. aitchisonii WT has an immune-stimulating effect via TNF-α and IFN-γ, and that M. aitchisonii WT is an immune-stimulating agent and can be produced as a functional food.

对本文的引用
  1. Wu Fang, Zhou Li-Wei, Yang Zhu-Liang, Bau Tolgor, Li Tai-Hui, Dai Yu-Cheng, Resource diversity of Chinese macrofungi: edible, medicinal and poisonous species, Fungal Diversity, 98, 1, 2019. Crossref

  2. Lee Soon-Young, Kim Min-Hee, Kim Seung-Hyun, Ahn Taeho, Kim Sung-Won, Kwak Yi-Seong, Cho Ik-Hyun, Nah Seung-Yeol, Cho Seung-Sik, Park Kyung Mok, Park Dae-Hun, Bae Chun-Sik, Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE2 pathways, Journal of Ginseng Research, 45, 4, 2021. Crossref

  3. Jiang Cuixia, Dong Quanmin, Xin Xiaoping, Degen Abraham Allan, Ding Luming, Effect of Chinese Herbs on Serum Biochemical Parameters, Immunity Indices, Antioxidant Capacity and Metabolomics in Early Weaned Yak Calves, Animals, 12, 17, 2022. Crossref

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