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Critical Reviews™ in Immunology

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ISSN Druckformat: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Immunological Mechanisms Involved In Experimental Peptide Immunotherapy of T-Cell-Mediated Diseases

Volumen 20, Ausgabe 6, 2000, 20 pages
DOI: 10.1615/CritRevImmunol.v20.i6.20
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ABSTRAKT

Current therapies for autoimmune diseases and allergy involve general immune suppression. However, the ideal therapy should specifically eliminate or modulate the (auto)pathogenic immune response or, alternatively, it should reinforce the regulatory response, without affecting the overall function of the immune system. This could be achieved by antigen-specific immunotherapy. Antigen-specific immunotherapy has received ample attention in the last years, and several clinical trials attempting to treat autoimmune diseases or allergy through the induction of antigen-specific tolerance or immune deviation have been conducted, albeit with varying success. Recent advances in our understanding of peripheral tolerance, regulatory T cells, and routes of antigen administration have resulted in better insight into the different working mechanisms and potential target molecules of antigen-specific immunotherapy. The experimental animal models and new technological developments force the pace in the development of these immunotherapies. The current review addresses several aspects of antigen-specific immunotherapies and focuses on the mechanisms of the different approaches in experimental autoimmune and allergy models.

REFERENZIERT VON
  1. Yang Lin, Jiang Hua, Shi Bizhi, Wang Huamao, Li Jinjun, Wang Hai, Yao Ming, Li Zonghai, Identification and characterization of Ch806 mimotopes, Cancer Immunology, Immunotherapy, 59, 10, 2010. Crossref

  2. Massey Emma J, Sundstedt Anette, Day Michael J, Corfield Gaynor, Anderton Stephen, Wraith David C, Intranasal peptide-induced peripheral tolerance: the role of IL-10 in regulatory T cell function within the context of experimental autoimmune encephalomyelitis, Veterinary Immunology and Immunopathology, 87, 3-4, 2002. Crossref

  3. Knittelfelder Regina, Riemer Angelika B, Jensen-Jarolim Erika, Mimotope vaccination – from allergy to cancer, Expert Opinion on Biological Therapy, 9, 4, 2009. Crossref

  4. Prakken Berent J., Roord Sarah, Van Kooten Peter J. S., Wagenaar Jos�e P. A., Van Eden Willem, Albani Salvatore, Wauben Marca H. M., Inhibition of adjuvant-induced arthritis by interleukin-10-driven regulatory cells induced via nasal administration of a peptide analog of an arthritis-related heat-shock protein 60 T cell epitope, Arthritis & Rheumatism, 46, 7, 2002. Crossref

  5. Riemer Angelika B., Kurz Harald, Klinger Markus, Scheiner Otto, Zielinski Christoph C., Jensen-Jarolim Erika, Vaccination With Cetuximab Mimotopes and Biological Properties of Induced Anti–Epidermal Growth Factor Receptor Antibodies, JNCI: Journal of the National Cancer Institute, 97, 22, 2005. Crossref

  6. Shi Xiao-Lian, Wang Li-Ping, Feng Xuan, Fan Dan-Dan, Zang Wei-Jin, Wang Bing, Zhou Jun, Inhibition of adjuvant-induced arthritis by nasal administration of novel synthetic peptides from heat shock protein 65, BMC Musculoskeletal Disorders, 15, 1, 2014. Crossref

  7. Angelini Giovanni, Bonamonte Domenico, Lucchese Alberta, Favia Gianfranco, Serpico Rosario, Mittelman Abraham, Simone Simone, Sinha Animesh A, Kanduc Darja, Preliminary data on Pemphigus vulgaris treatment by a proteomics-defined peptide: a case report, Journal of Translational Medicine, 4, 1, 2006. Crossref

  8. GARMAN R D, MUNROE K, RICHARDS S M, Methotrexate reduces antibody responses to recombinant human α-galactosidase A therapy in a mouse model of Fabry disease, Clinical and Experimental Immunology, 137, 3, 2004. Crossref

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