Abo Bibliothek: Guest
Critical Reviews™ in Immunology

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Enzymatic and Extraenzymatic Role of Adenosine Deaminase 1 in T-Cell-Dendritic Cell Contacts and in Alterations of the Immune Function

Volumen 27, Ausgabe 6, 2007, pp. 495-509
DOI: 10.1615/CritRevImmunol.v27.i6.10
Get accessGet access

ABSTRAKT

Adenosine deaminase 1 (ADA1) is an enzyme of the purine metabolism whose congenital defect leads to severe combined immunodeficiency (SCID). Although classically considered a cytosolic enzyme, early evidence from work in brain synaptosomes suggested that the enzyme could be an ectoenzyme. In lymphoid cells, ectoenzymatic activity of ADA1 was also found. The obvious role of this enzyme located on the cell surface of lymphocytes and monocytes was to deaminate adenosine, making it less available for uptaking and metabolism, and also for adenosine-receptor activation. Quite unexpectedly, ADA1 was shown to act extraenzymatically. In addition, cell surface ADA1-binding proteins have been identified. Interestingly, the interaction of ADA1 with these anchoring proteins leads to costimulation of T-cell activation. Recent studies performed with professional antigen-presenting cells and T lymphocytes have shown that ADA1 can bridge the two cell types together by a “cross-linking” established between different anchoring molecules in each cell. Some aspects of ADA action are similar to that of growth factors. In fact, ADA1 is a member of the adenosine deaminase growth factor (ADGF) family. Some molecular mechanisms that occur in ADA-related SCID and the role ADA1 may play in acquired immunodeficiency are also reviewed here.

REFERENZIERT VON
  1. Pimentel Victor Camera, Gomes Jéssica Lopes, Zanini Daniela, Abdalla Fátima Husein, da Costa Pauline, Gonçalves Jamile Fabbrin, Duarte Marta Maria Medeiros Frescura, Moretto Maria Beatriz, Morsch Vera Maria, Schetinger Maria Rosa Chitolina, Evaluation of acetylcholinesterase and adenosine deaminase activities in brain and erythrocytes and proinflammatory cytokine levels in rats submitted to neonatal hypoxia-ischemia model, Molecular and Cellular Biochemistry, 378, 1-2, 2013. Crossref

  2. Seo J., Osorio J.S., Loor J.J., Purinergic signaling gene network expression in bovine polymorphonuclear neutrophils during the peripartal period, Journal of Dairy Science, 96, 12, 2013. Crossref

  3. Pimentel Victor Camera, Zanini Daniela, Cardoso Andréia Machado, Schmatz Roberta, Bagatini Margarete Dulce, Gutierres Jessié Martins, Carvalho Fabiano, Gomes Jéssica Lopes, Rubin Maribel, Morsch Vera Maria, Moretto Maria Beatriz, Colino-Oliveira Mariana, Sebastião Ana Maria, Schetinger Maria Rosa Chitolina, Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats, Neurochemical Research, 38, 4, 2013. Crossref

  4. Napolioni Valerio, Carpi Francesco M., Giannì Paola, Sacco Roberto, Di Blasio Luca, Mignini Fiorenzo, Lucarini Nazzareno, Persico Antonio M., Age- and gender-specific epistasis between ADA and TNF-α influences human life-expectancy, Cytokine, 56, 2, 2011. Crossref

  5. Yadav Sarika, Saxena Jitendra Kumar, Dwivedi U.N., Purification and characterization of Plasmodium yoelii adenosine deaminase, Experimental Parasitology, 129, 4, 2011. Crossref

  6. Climent Núria, Martinez‐Navio José M, Gil Cristina, Garcia Felipe, Rovira Cristina, Hurtado Carmen, Miralles Laia, Gatell José M, Gallart Teresa, Mallol Josefa, Lluis Carme, Franco Rafael, Adenosine deaminase enhances T‐cell response elicited by dendritic cells loaded with inactivated HIV, Immunology & Cell Biology, 87, 8, 2009. Crossref

  7. Junger Wolfgang G., Immune cell regulation by autocrine purinergic signalling, Nature Reviews Immunology, 11, 3, 2011. Crossref

  8. Bopp A., De Bona K.S., Bellé L.P., Moresco R.N., Moretto M.B., Syzygium cuminiinhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients, Fundamental & Clinical Pharmacology, 23, 4, 2009. Crossref

  9. Cortés Antoni, Gracia Eduard, Moreno Estefania, Mallol Josefa, Lluís Carme, Canela Enric I., Casadó Vicent, Moonlighting Adenosine Deaminase: A Target Protein for Drug Development, Medicinal Research Reviews, 35, 1, 2015. Crossref

  10. Napolioni Valerio, Lucarini Nazzareno, Gender-specific association of ADA genetic polymorphism with human longevity, Biogerontology, 11, 4, 2010. Crossref

  11. Pimentel Victor Camera, Moretto Maria Beatriz, Oliveira Mariana Colino, Zanini Daniela, Sebastião Ana Maria, Schetinger Maria Rosa Chitolina, Neuroinflammation after neonatal hypoxia–ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult, Molecular and Cellular Biochemistry, 403, 1-2, 2015. Crossref

  12. Spina C., Saccucci P., Cozzoli E., Bottini E., Gloria-Bottini F., A Study of Three Polymorphic Sites of ADA Gene in Colon Cancer, Cancer Investigation, 28, 10, 2010. Crossref

  13. Koch-Nolte Friedrich, Fischer Stefan, Haag Friedrich, Ziegler Mathias, Compartmentation of NAD+-dependent signalling, FEBS Letters, 585, 11, 2011. Crossref

  14. Martinez‐Navio Jose M, Climent Nuria, Gallart Teresa, Lluis Carme, Franco Rafael, An old enzyme for current needs: adenosine deaminase and a dendritic cell vaccine for HIV, Immunology & Cell Biology, 90, 6, 2012. Crossref

  15. Gloria-Bottini F., Magrini A., Cozzoli E., Bergamaschi A., Bottini E., ADA genetic polymorphism and the effect of smoking on neonatal bilirubinemia and developmental parameters, Early Human Development, 84, 11, 2008. Crossref

  16. Pimentel V.C., Bellé L.P., Pinheiro F.V., De Bona K.S., Da Luz S.C.A., Moretto M.B., Adenosine deaminase activity, lipid peroxidation and astrocyte responses in the cerebral cortex of rats after neonatal hypoxia ischemia, International Journal of Developmental Neuroscience, 27, 8, 2009. Crossref

  17. Gong Quan, Rajagopalan Sanjay, Zhong Jixin, Dpp4 inhibition as a therapeutic strategy in cardiometabolic disease: Incretin-dependent and -independent function, International Journal of Cardiology, 197, 2015. Crossref

  18. Gloria-Bottini Fulvia, Nicotra Maria, Amante Ada, Ambrosi Sara, Cozzoli Eliana, Saccucci Patrizia, Bottini Egidio, Magrini Andrea, Effect of ADA1 mother-fetus and wife-husband phenotypic differences on the ratio birth weight/placental weight in fertile women and on reproductive success in couples with RSA, American Journal of Human Biology, 24, 2, 2012. Crossref

  19. Kaljas Yuliia, Liu Chengqian, Skaldin Maksym, Wu Chengxiang, Zhou Qing, Lu Yuanan, Aksentijevich Ivona, Zavialov Andrey V., Human adenosine deaminases ADA1 and ADA2 bind to different subsets of immune cells, Cellular and Molecular Life Sciences, 74, 3, 2017. Crossref

  20. Legger G. Elizabeth, Frenkel J., Autoinflammatory Disorders in Children, in Pediatrics in Systemic Autoimmune Diseases, 11, 2016. Crossref

  21. Casanova Víctor, Naval-Macabuhay Isaac, Massanella Marta, Rodríguez-García Marta, Blanco Julià, Gatell José M., García Felipe, Gallart Teresa, Lluis Carme, Mallol Josefa, Franco Rafael, Climent Núria, McCormick Peter J., Ahuja Sunil K., Adenosine Deaminase Enhances the Immunogenicity of Human Dendritic Cells from Healthy and HIV-Infected Individuals, PLoS ONE, 7, 12, 2012. Crossref

  22. Orlova Marianna, Cobat Aurélie, Huong Nguyen Thu, Ba Nguyen Ngoc, Van Thuc Nguyen, Spencer John, Nédélec Yohann, Barreiro Luis, Thai Vu Hong, Abel Laurent, Alcaïs Alexandre, Schurr Erwin, Sirugo Giorgio, Gene Set Signature of Reversal Reaction Type I in Leprosy Patients, PLoS Genetics, 9, 7, 2013. Crossref

  23. Yegutkin Gennady G., Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities, Critical Reviews in Biochemistry and Molecular Biology, 49, 6, 2014. Crossref

  24. Zavialov Anton V., Yu Xiaodi, Spillmann Dorothe, Lauvau Grégoire, Zavialov Andrey V., Structural Basis for the Growth Factor Activity of Human Adenosine Deaminase ADA2, Journal of Biological Chemistry, 285, 16, 2010. Crossref

  25. Moreno Estefanía, Canet Júlia, Gracia Eduard, Lluís Carme, Mallol Josefa, Canela Enric I., Cortés Antoni, Casadó Vicent, Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins, Frontiers in Pharmacology, 9, 2018. Crossref

  26. Meyts Isabelle, Aksentijevich Ivona, Deficiency of Adenosine Deaminase 2 (DADA2): Updates on the Phenotype, Genetics, Pathogenesis, and Treatment, Journal of Clinical Immunology, 38, 5, 2018. Crossref

  27. Moens Leen, Hershfield Michael, Arts Katrijn, Aksentijevich Ivona, Meyts Isabelle, Human adenosine deaminase 2 deficiency: A multi-faceted inborn error of immunity, Immunological Reviews, 287, 1, 2019. Crossref

  28. Martinez-Navio José M., Casanova Víctor, Pacheco Rodrigo, Naval-Macabuhay Isaac, Climent Núria, Garcia Felipe, Gatell José M., Mallol Josefa, Gallart Teresa, Lluis Carme, Franco Rafael, Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+T cells, Journal of Leukocyte Biology, 89, 1, 2011. Crossref

  29. Lauri Natalia, Bazzi Zaher, Alvarez Cora L., Denis María F. Leal, Schachter Julieta, Herlax Vanesa, Ostuni Mariano A., Schwarzbaum Pablo J., ATPe Dynamics in Protozoan Parasites. Adapt or Perish, Genes, 10, 1, 2018. Crossref

  30. Tardif Virginie, Muir Roshell, Cubas Rafael, Chakhtoura Marita, Wilkinson Peter, Metcalf Talibah, Herro Rana, Haddad Elias K., Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV, Nature Communications, 10, 1, 2019. Crossref

  31. Kutryb-Zajac Barbara, Mierzejewska Paulina, Slominska Ewa M., Smolenski Ryszard T., Therapeutic Perspectives of Adenosine Deaminase Inhibition in Cardiovascular Diseases, Molecules, 25, 20, 2020. Crossref

  32. Franco Rafael, Rivas-Santisteban Rafael, Navarro Gemma, Reyes-Resina Irene, Adenosine Receptor Antagonists to Combat Cancer and to Boost Anti-Cancer Chemotherapy and Immunotherapy, Cells, 10, 11, 2021. Crossref

  33. Martinez-Navio Jose, Neurological complications during HIV infection, Exploration of Neuroprotective Therapy, 2021. Crossref

  34. Kutryb-Zajac Barbara, Harasim Gabriela, Jedrzejewska Agata, Krol Oliwia, Braczko Alicja, Jablonska Patrycja, Mierzejewska Paulina, Zielinski Jacek, Slominska Ewa M., Smolenski Ryszard. T., Macrophage-Derived Adenosine Deaminase 2 Correlates with M2 Macrophage Phenotype in Triple Negative Breast Cancer, International Journal of Molecular Sciences, 22, 7, 2021. Crossref

  35. Senger Mario Roberto, Rosemberg Denis Broock, Seibt Kelly Juliana, Dias Renato Dutra, Bogo Maurício Reis, Bonan Carla Denise, Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain, NeuroToxicology, 31, 3, 2010. Crossref

  36. Jiang Zhuoran, Wang Chao, Wu Zixin, Chen Kun, Yang Wei, Deng Hexiang, Song Heng, Zhou Xiang, Enzymatic deamination of the epigenetic nucleoside N6-methyladenosine regulates gene expression, Nucleic Acids Research, 49, 21, 2021. Crossref

  37. Rawat Ravindra Singh, Kumar Sanjit, Understanding the mode of inhibition and molecular interaction of taxifolin with human adenosine deaminase, Journal of Biomolecular Structure and Dynamics, 2021. Crossref

  38. Gillerman Irina, Fischer Bilha, Investigations into the Origin of the Molecular Recognition of Several Adenosine Deaminase Inhibitors, Journal of Medicinal Chemistry, 54, 1, 2011. Crossref

  39. Chakhtoura Marita, Fang Mike, Cubas Rafael, O’Connor Margaret H., Nichols Carmen N., Richardson Brian, Talla Aarthi, Moir Susan, Cameron Mark J., Tardif Virginie, Haddad Elias K., Silvestri Guido, Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling, PLOS Pathogens, 17, 7, 2021. Crossref

  40. Dyakova M. E., Serebryanaya N. B., Kiryukhina L. D., Esmedlyaeva D. S., Yablonskiy P. K., Adenosine-regulated mechanisms in the pathogenesis of ventilation disorders in patients with pulmonary tuberculosis, Russian Journal of Infection and Immunity, 11, 4, 2021. Crossref

  41. Thammavongsa Vilasack, Missiakas Dominique M., Schneewind Olaf, Staphylococcus aureus Degrades Neutrophil Extracellular Traps to Promote Immune Cell Death , Science, 342, 6160, 2013. Crossref

  42. Liu Jingchun, Hong Shasha, Yang Jiang, Zhang Xiaoyi, Wang Ying, Wang Haoyu, Peng Jiaxin, Hong Li, Targeting purine metabolism in ovarian cancer, Journal of Ovarian Research, 15, 1, 2022. Crossref

  43. Kutryb-Zajac Barbara, Kawecka Ada, Caratis Fionä, Urbanowicz Krzysztof, Braczko Alicja, Furihata Tomomi, Karaszewski Bartosz, Smolenski Ryszard T., Rutkowska Aleksandra, The impaired distribution of adenosine deaminase isoenzymes in multiple sclerosis plasma and cerebrospinal fluid, Frontiers in Molecular Neuroscience, 15, 2022. Crossref

Zukünftige Artikel

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen Preise und Aborichtlinien Begell House Kontakt Language English 中文 Русский Português German French Spain