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Critical Reviews™ in Oncogenesis

Erscheint 4 Ausgaben pro Jahr

ISSN Druckformat: 0893-9675

ISSN Online: 2162-6448

SJR: 0.395 SNIP: 0.322 CiteScore™:: 2.5 H-Index: 54

Indexed in

Therapeutic Potential of Nitric Oxide Donors in Cancer: Focus on Angiogenesis

Volumen 21, Ausgabe 5-6, 2016, pp. 447-458
DOI: 10.1615/CritRevOncog.2017021114
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ABSTRAKT

A new challenge to overcoming tumor resistance to conventional treatment is represented by the development of novel nitric oxide (NO) donors. It is now clear that while low doses of NO have proneoplastic properties, high doses exert antitumor/antiangiogenic activities through multiple mechanisms. This review focuses on the role of exogenous NO in cancer therapy and reports the state of the art regarding different NO-donating agents in cancer treatment, particularly in relation to angiogenesis inhibition.

REFERENZIERT VON
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  2. Ciccone Valerio, Morbidelli Lucia, Antitumor Effect of a Metal-Nonoate Through Angiogenesis Impairment, in Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders, 2019. Crossref

  3. Amedei Amedeo, Morbidelli Lucia, Circulating Metabolites Originating from Gut Microbiota Control Endothelial Cell Function, Molecules, 24, 21, 2019. Crossref

  4. Morbidelli Lucia, Genah Shirley, Cialdai Francesca, Effect of Microgravity on Endothelial Cell Function, Angiogenesis, and Vessel Remodeling During Wound Healing, Frontiers in Bioengineering and Biotechnology, 9, 2021. Crossref

  5. Ciccone Valerio, Filippelli Arianna, Bacchella Chiara, Monzani Enrico, Morbidelli Lucia, The Nitric Oxide Donor [Zn(PipNONO)Cl] Exhibits Antitumor Activity through Inhibition of Epithelial and Endothelial Mesenchymal Transitions, Cancers, 14, 17, 2022. Crossref

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