Abo Bibliothek: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

A New Transcription Factor Family Associated with Human Leukemias

Volumen 5, Ausgabe 3-4, 1995, pp. 337-364
DOI: 10.1615/CritRevEukarGeneExpr.v5.i3-4.60
Get accessGet access

ABSTRAKT

The proteins known as the polyoma enhancer binding protein 2 or core-binding factor (PEBP2/CBF) are heterodimeric transcription factors that contain a DNA-binding subunit (CBFα), and a subunit that does not bind DNA independently (CBFβ). PEBP2 and CBF were identified independently as proteins that regulate transcription of viral and cellular enhancers, and also as proteins whose genes are disrupted by chromosomal abnormalities in human leukemias. This review traces the history of the discovery of the PEBP2 and CBF protein family and describes the biochemical properties of the normal and oncogenic forms of these proteins.

SCHLÜSSELWÖRTER: CBF, PEBP2, AML1, CBFB, t(8, 21), t(3, 21), t(12, 21), inv(16).
REFERENZIERT VON
  1. Lian Jane B., Stein Gary S., Stein Janet L., Van Wijnen Andre J., , 55, 1998. Crossref

  2. Tsai Chih-Cheng, Kramer Sunita G., Gergen J. Peter, Pair-rule generunt restrictsorthodenticle expression to the presumptive head of theDrosophila embryo, Developmental Genetics, 23, 1, 1998. Crossref

  3. Suad Oded, Eyal Eran, Blumenzweig Immanuel, Kessler Naama, Levanon Ditsa, Groner Yoram, Shakked Zippora, RUN-CBFβ Interaction inC. elegans: Computational Prediction and Experimental Verification, Journal of Biomolecular Structure and Dynamics, 24, 4, 2007. Crossref

  4. KARSENTY GERARD, KRONENBERG HENRY M., Postnatal Bone Growth, in Pediatric Bone, 2003. Crossref

  5. Robins Diane M, , 78, 2004. Crossref

  6. Raveh Eli, Cohen Shulamit, Levanon Ditsa, Groner Yoram, Gat Uri, Runx3 is involved in hair shape determination, Developmental Dynamics, 233, 4, 2005. Crossref

  7. Khan Aneal, Hyde R. Katherine, Dutra Amalia, Mohide Patrick, Liu Paul, Core binding factor beta (CBFB) haploinsufficiency due to an interstitial deletion at 16q21q22 resulting in delayed cranial ossification, cleft palate, congenital heart anomalies, and feeding difficulties but favorable outcome, American Journal of Medical Genetics Part A, 140A, 21, 2006. Crossref

  8. Prince Michelle, Banerjee Chaitali, Javed Amjad, Green Jack, Lian Jane B., Stein Gary S., Bodine Peter V.N., Komm Barry S., Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts, Journal of Cellular Biochemistry, 80, 3, 2001. Crossref

  9. Ardura Juan A, Sanz Ana B, Ortiz Alberto, Esbrit Pedro, Parathyroid hormone–related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2, Kidney International, 83, 5, 2013. Crossref

  10. Yamashiro Takashi, Runx signaling and dental stem cells, Journal of Oral Biosciences, 55, 1, 2013. Crossref

  11. Banerjee Chaitali, McCabe Laura R., Choi Je-Yong, Hiebert Scott W., Stein Janet L., Stein Gary S., Lian Jane B., Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex, Journal of Cellular Biochemistry, 66, 1, 1997. Crossref

  12. Lian Jane B., Stein Gary S., Stein Janet L., van Wijnen André J., Osteocalcin gene promoter: Unlocking the secrets for regulation of osteoblast growth and differentiation, Journal of Cellular Biochemistry, 72, S30-31, 1998. Crossref

  13. McNeil Sandra, Javed Amjad, Harrington Kimberly S., Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies, Journal of Cellular Biochemistry, 79, 1, 2000. Crossref

  14. Schmitt John M., Hwang Kun, Winn Shelley R., Hollinger Jeffrey O., Bone morphogenetic proteins: An update on basic biology and clinical relevance, Journal of Orthopaedic Research, 17, 2, 1999. Crossref

  15. Nasiadka Andrzej, Dietrich Bruce H., Krause Henry M., Anterior-posterior patterning in the Drosophila embryo, in Gene Expression at the Beginning of Animal Development, 12, 2002. Crossref

  16. Ducy Patricia, CBFA1: A molecular switch in osteoblast biology, Developmental Dynamics, 219, 4, 2000. Crossref

  17. Meyers Shari, Hiebert Scott W., Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia, Journal of Cellular Biochemistry, 79, S35, 2000. Crossref

  18. Gordon Jeffrey A., Pockwinse Shirwin M., Stewart F. Marc, Quesenberry Peter J., Nakamura Tatsuya, Croce Carlo M., Lian Jane B., Stein Janet L., van Wijnen Andr� J., Stein Gary S., Modified intranuclear organization of regulatory factors in human acute leukemias: Reversal after treatment, Journal of Cellular Biochemistry, 77, 1, 2000. Crossref

  19. Fenrick Randy, Hiebert Scott W., Role of histone deacetylases in acute leukemia, Journal of Cellular Biochemistry, 72, S30-31, 1998. Crossref

  20. Okuda Tsukasa, Nishimura Motohiro, Nakao Mitsushige, Fujitaa Yasuko, RUNX1/AML1: A Central Player in Hematopoiesis, International Journal of Hematology, 74, 3, 2001. Crossref

  21. Le Xiao-Feng, Claxton David, Kornblau Steve, Fan You-Hong, Mu Zhao-Mei, Chang Kun-Sang, Characterization of the ETO and AML1-ETO proteins involved in the 8;21 translocation in acute myelogenous leukemia, European Journal of Haematology, 60, 4, 2009. Crossref

  22. Jaster Robert, Baek Kwang-Hyun, D’Andrea Alan D., Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the DUB-1 gene, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1446, 3, 1999. Crossref

  23. Bowers Sarion R., Calero-Nieto Fernando J., Valeaux Stephanie, Fernandez-Fuentes Narcis, Cockerill Peter N., Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer, Nucleic Acids Research, 38, 18, 2010. Crossref

  24. Ohshima Hayato, Oral biosciences: The annual review 2013, Journal of Oral Biosciences, 56, 1, 2014. Crossref

  25. Solh Melhem, Yohe Sophia, Weisdorf Daniel, Ustun Celalettin, Core-binding factor acute myeloid leukemia: Heterogeneity, monitoring, and therapy, American Journal of Hematology, 89, 12, 2014. Crossref

  26. Graves Barbara J., Petersen Jeannine M., , 75, 1998. Crossref

  27. Tian Fei, Wu Mengrui, Deng Lianfu, Zhu Guochun, Ma Junqing, Gao Bo, Wang Lin, Li Yi-Ping, Chen Wei, Core Binding Factor Beta (Cbfβ) Controls the Balance of Chondrocyte Proliferation and Differentiation by Upregulating Indian hedgehog (Ihh) Expression and Inhibiting Parathyroid Hormone-Related Protein Receptor (PPR) Expression in Postnatal Cartilage and, Journal of Bone and Mineral Research, 29, 7, 2014. Crossref

  28. LACAUD GEORGES, ROBERTSON SCOTT, PALIS JAMES, KENNEDY MARION, KELLER GORDON, Regulation of Hemangioblast Development, Annals of the New York Academy of Sciences, 938, 1, 2006. Crossref

  29. Andreasson Patrik, Schwaller Juerg, Anastasiadou Ema, Aster Jon, Gilliland D.Gary, The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo, Cancer Genetics and Cytogenetics, 130, 2, 2001. Crossref

  30. Nagata Takashi, Werner Milton H, Functional mutagenesis of AML1/RUNX1 and PEBP2β/CBFβ define distinct, non-overlapping sites for DNA recognition and heterodimerization by the runt domain1 1Edited by M. Yaniv, Journal of Molecular Biology, 308, 2, 2001. Crossref

  31. Tahirov Tahir H., Inoue-Bungo Taiko, Morii Hisayuki, Fujikawa Atsushi, Sasaki Motoko, Kimura Kazumi, Shiina Masaaki, Sato Ko, Kumasaka Takashi, Yamamoto Masaki, Ishii Shunsuke, Ogata Kazuhiro, Structural Analyses of DNA Recognition by the AML1/Runx-1 Runt Domain and Its Allosteric Control by CBFβ, Cell, 104, 5, 2001. Crossref

  32. Dittmer Jürgen, Nordheim Alfred, Ets transcription factors and human disease, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1377, 2, 1998. Crossref

  33. Lian Jane B., Stein Gary S., Stein Janet L., Wijnen AndrÉ Van, Mccabe Laura, Banerjee Chaitali, Hoffmann Heidi, The Osteocalcin Gene Promoter Provides a Molecular Blueprint for Regulatory Mechanisms Controlling Bone Tissue Formation: Role of Transcription Factors Involved in Development, Connective Tissue Research, 35, 1-4, 1996. Crossref

  34. Kang Chang-Joong, Sheridan Colleen, Koshland Marian Elliott, A Stage-Specific Enhancer of Immunoglobulin J Chain Gene Is Induced by Interleukin-2 in a Presecretor B Cell Stage, Immunity, 8, 3, 1998. Crossref

  35. Denkinger Diane J, Kawahara Rodney S, Mutex: a method for simultaneous footprinting and determination of base pair specificity for transcription factor binding sites, Analytical Biochemistry, 321, 1, 2003. Crossref

  36. Karsenty Gerard, Role of Cbfa1 in osteoblast differentiation and function, Seminars in Cell & Developmental Biology, 11, 5, 2000. Crossref

  37. Adya N, Castilla L.H, Liu P.P, Function of CBFβ/Bro proteins, Seminars in Cell & Developmental Biology, 11, 5, 2000. Crossref

  38. Park Sung-Kyun, Lim Jung-Hyun, Kang Chang-Joong, Crlz1 activates transcription by mobilizing cytoplasmic CBFβ into the nucleus, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1789, 11-12, 2009. Crossref

  39. San Martin Inga A., Varela Nelson, Gaete Marcia, Villegas Karina, Osorio Mariana, Tapia Julio C., Antonelli Marcelo, Mancilla Edna E., Pereira Barry P., Nathan Saminathan S., Lian Jane B., Stein Janet L., Stein Gary S., van Wijnen Andre J., Galindo Mario, Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfβ in osteosarcoma cells, Journal of Cellular Physiology, 221, 3, 2009. Crossref

  40. Otto Florian, Thornell Anders P, Crompton Tessa, Denzel Angela, Gilmour Kimberly C, Rosewell Ian R, Stamp Gordon W.H, Beddington Rosa S.P, Mundlos Stefan, Olsen Bjorn R, Selby Paul B, Owen Michael J, Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development, Cell, 89, 5, 1997. Crossref

  41. Ducy Patricia, Zhang Rui, Geoffroy Valérie, Ridall Amy L, Karsenty Gérard, Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation, Cell, 89, 5, 1997. Crossref

  42. Cho Sun-Jung, Kang Chang-Joong, A Stat5-overlapping site is critical for the IgJ enhancer activity in the plasma cells and bound by a ubiquitous protein, Biochemical and Biophysical Research Communications, 338, 4, 2005. Crossref

  43. Wolff Linda, Contribution of oncogenes and tumor suppressor genes to myeloid leukemia, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1332, 3, 1997. Crossref

  44. Bartfeld Deborah, Shimon Linda, Couture Graeme C., Rabinovich Dov, Frolow Felix, Levanon Ditsa, Groner Yoram, Shakked Zippora, DNA Recognition by the RUNX1 Transcription Factor Is Mediated by an Allosteric Transition in the RUNT Domain and by DNA Bending, Structure, 10, 10, 2002. Crossref

  45. Browne Gillian, Taipaleenmäki Hanna, Bishop Nicole M., Madasu Sharath C., Shaw Leslie M., van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion, Journal of Cellular Physiology, 230, 10, 2015. Crossref

  46. Raveh Eli, Cohen Shulamit, Levanon Ditsa, Negreanu Varda, Groner Yoram, Gat Uri, Dynamic expression of Runx1 in skin affects hair structure, Mechanisms of Development, 123, 11, 2006. Crossref

  47. Karsenty Gerard, Structural differences between runx1 and runx2 account for the hierarchy of function for Cbfa1beta, BoneKEy-Osteovision, 2003. Crossref

  48. Lim Kyung-Eun, Park Na-Rae, Che Xiangguo, Han Min-Su, Jeong Jae-Hwan, Kim Shin-Yoon, Park Clara Yongjoo, Akiyama Haruhiko, Kim Jung-Eun, Ryoo Hyun-Mo, Stein Janet L, Lian Jane B, Stein Gary S, Choi Je-Yong, Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass via Stabilization of Runx2 in Mice, Journal of Bone and Mineral Research, 30, 4, 2015. Crossref

  49. Wang Qing, Stacy Terryl, Miller Janelle D, Lewis Amy F, Gu Ting-Lei, Huang Xuemei, Bushweller John H, Bories Jean-Christophe, Alt Frederick W, Ryan Gabriella, Liu Pu Paul, Wynshaw-Boris Anthony, Binder Michael, Marín-Padilla Miguel, Sharpe Arlene H, Speck Nancy A, The CBFβ Subunit Is Essential for CBFα2 (AML1) Function In Vivo, Cell, 87, 4, 1996. Crossref

  50. Levanon Ditsa, Eisenstein Miriam, Groner Yoram, Site-directed mutagenesis supports a three-dimensional model of the runt domain 1 1Edited by A. Klug, Journal of Molecular Biology, 277, 3, 1998. Crossref

  51. Elefanty Andrew G., Robb Lorraine, Glenn Begley C., 10 Factors involved in leukaemogenesis and haemopoiesis, Baillière's Clinical Haematology, 10, 3, 1997. Crossref

  52. Lamoureux Jason S., Maynes Jason T., Mark Glover J.N., Recognition of 5′-YpG-3′ Sequences by Coupled Stacking/Hydrogen Bonding Interactions with Amino Acid Residues, Journal of Molecular Biology, 335, 2, 2004. Crossref

  53. Park Na-Rae, Lim Kyung-Eun, Han Min-Su, Che Xiangguo, Park Clara Yongjoo, Kim Jung-Eun, Taniuchi Ichiro, Bae Suk-Chul, Choi Je-Yong, Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiation, Journal of Cellular Physiology, 231, 1, 2016. Crossref

  54. Cherry Athena M, Bangs Charles D, Jones Patty, Hall Scott, Natkunam Yasodha, A unique AML1 (CBF2A) rearrangement, t(1;21)(p32;q22), observed in a patient with acute myelomonocytic leukemia, Cancer Genetics and Cytogenetics, 129, 2, 2001. Crossref

  55. Unnikrishnan Ashwin, Guan Yi F., Huang Yizhou, Beck Dominik, Thoms Julie A. I., Peirs Sofie, Knezevic Kathy, Ma Shiyong, de Walle Inge V., de Jong Ineke, Ali Zara, Zhong Ling, Raftery Mark J., Taghon Tom, Larsson Jonas, MacKenzie Karen L., Van Vlierberghe Pieter, Wong Jason W. H., Pimanda John E., A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of anERG-driven transcriptional network, Nucleic Acids Research, 44, 22, 2016. Crossref

  56. Nakamura Takayuki, Ohno Tetsuya, Hirota Kiichi, Nishiyama Akira, Nakamura Hajime, Wada Hiromi, Yodoi Junji, Mouse glutaredoxin — cDNA cloning, high level expression inE. coliand its possible implication in redox regulation of the DNA binding activity in transcription factor PEBP2, Free Radical Research, 31, 4, 1999. Crossref

  57. Browne Gillian, Dragon Julie A., Hong Deli, Messier Terri L., Gordon Jonathan A. R., Farina Nicholas H., Boyd Joseph R., VanOudenhove Jennifer J., Perez Andrew W., Zaidi Sayyed K., Stein Janet L., Stein Gary S., Lian Jane B., MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells, Tumor Biology, 37, 7, 2016. Crossref

  58. Barutcu A. Rasim, Hong Deli, Lajoie Bryan R., McCord Rachel Patton, van Wijnen Andre J., Lian Jane B., Stein Janet L., Dekker Job, Imbalzano Anthony N., Stein Gary S., RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1859, 11, 2016. Crossref

  59. Karsli-Ceppioglu Seher, Dagdemir Aslihan, Judes Gaëlle, Lebert André, Penault-Llorca Frédérique, Bignon Yves-Jean, Bernard-Gallon Dominique, The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer, Scientific Reports, 7, 1, 2017. Crossref

  60. Varshney Bhavna, Agnihotram Sudhakar, Tan Yee-Joo, Baric Ralph, Lal Sunil K., Sambhara Suryaprakash, SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b, PLoS ONE, 7, 1, 2012. Crossref

  61. Rubnitz Jeffrey E., Look A. Thomas, Molecular Genetics of Childhood Leukemias, Journal of Pediatric Hematology/Oncology, 20, 1, 1998. Crossref

  62. Shi Meng-Jiao, Park Seok-Rae, Kim Pyeung-Hyeun, Stavnezer Janet, Roles of Ets proteins, NF-κB and nocodazole in regulating induction of transcription of mouse germline Ig α RNA by transforming growth factor-β1, International Immunology, 13, 6, 2001. Crossref

  63. Shiraha Hidenori, Horiguchi Shigeru, Okada Hiroyuki, RUNX3, in Encyclopedia of Signaling Molecules, 2016. Crossref

  64. Shiraha Hidenori, Horiguchi Shigeru, Okada Hiroyuki, RUNX3, in Encyclopedia of Signaling Molecules, 2018. Crossref

  65. Lymar Elena S., Clark Ann M., Reeves Raymond, Griswold Michael D., Clusterin Gene in Rat Sertoli Cells Is Regulated by a Core-Enhancer Element, Biology of Reproduction, 63, 5, 2000. Crossref

  66. Mahlknecht Ulrich, Hoelzer Dieter, Histone Acetylation Modifiers in the Pathogenesis of Malignant Disease, Molecular Medicine, 6, 8, 2000. Crossref

  67. Hantel Andrew, Stock Wendy, Kosuri Satyajit, Molecular Minimal Residual Disease Testing in Acute Myeloid Leukemia: A Review for the Practicing Clinician, Clinical Lymphoma Myeloma and Leukemia, 18, 10, 2018. Crossref

  68. Reginato Anthony M., Wang WenFang, Olsen Bjorn R., Developmental Biology of Bone, in Osteoporosis, 2001. Crossref

  69. Lian Jane B., Stein Gary S., Osteoblast Biology, in Osteoporosis, 2001. Crossref

  70. Bartolo Claire, Viswanatha David S., Molecular Diagnosis in Pediatric Acute Leukemias, Clinics in Laboratory Medicine, 20, 1, 2000. Crossref

  71. Engel Michael E., Hiebert Scott W., Proleukemic RUNX1 and CBFβ Mutations in the Pathogenesis of Acute Leukemia, in Acute Myelogenous Leukemia, 145, 2009. Crossref

  72. Lim Jung-Hyun, Cho Sun-Jung, Park Sung-Kyun, Kim Jiyoung, Cho Daeho, Lee Wang Jae, Kang Chang-Joong, Stage-Specific Expression of Two NeighboringCrlz1andIgJGenes during B Cell Development Is Regulated by Their Chromatin Accessibility and Histone Acetylation, The Journal of Immunology, 177, 8, 2006. Crossref

  73. Okuda Tsukasa, Cai Zhongling, Yang Shouli, Lenny Noel, Lyu Chuhl-joo, van Deursen Jan M.A., Harada Hironori, Downing James R., Expression of a Knocked-In AML1-ETO Leukemia Gene Inhibits the Establishment of Normal Definitive Hematopoiesis and Directly Generates Dysplastic Hematopoietic Progenitors, Blood, 91, 9, 1998. Crossref

  74. Telfer Janice C., Hedblom Emmett E., Anderson Michele K., Laurent Micheline N., Rothenberg Ellen V., Localization of the Domains in Runx Transcription Factors Required for the Repression of CD4 in Thymocytes, The Journal of Immunology, 172, 7, 2004. Crossref

  75. Stavnezer J., Molecular Processes that Regulate Class Switching, in Signal Transduction and the Coordination of B Lymphocyte Development and Function II, 245/2, 2000. Crossref

  76. Guidez Fabien, Petrie Kevin, Ford Anthony M., Lu Huafeng, Bennett Caroline A., MacGregor Angus, Hannemann Jürgen, Ito Yoshiaki, Ghysdael Jacques, Greaves Mel, Wiedemann Leanne M., Zelent Arthur, Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein, Blood, 96, 7, 2000. Crossref

  77. Stulberg Jennifer, Kamel-Reid Suzanne, Chun Kathy, Tokunaga Jason, Wells Richard A., Molecular Analysis of a New Variant of the CBFβ - MYH11 Gene Fusion, Leukemia & Lymphoma, 43, 10, 2002. Crossref

  78. Okuda Tsukasa, Cai Zhongling, Yang Shouli, Lenny Noel, Lyu Chuhl-joo, van Deursen Jan M.A., Harada Hironori, Downing James R., Expression of a Knocked-In AML1-ETO Leukemia Gene Inhibits the Establishment of Normal Definitive Hematopoiesis and Directly Generates Dysplastic Hematopoietic Progenitors, Blood, 91, 9, 1998. Crossref

  79. Guidez Fabien, Petrie Kevin, Ford Anthony M., Lu Huafeng, Bennett Caroline A., MacGregor Angus, Hannemann Jürgen, Ito Yoshiaki, Ghysdael Jacques, Greaves Mel, Wiedemann Leanne M., Zelent Arthur, Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein, Blood, 96, 7, 2000. Crossref

  80. Zhang Yanming, Rowley Janet D., Chromatin structural elements and chromosomal translocations in leukemia, DNA Repair, 5, 9-10, 2006. Crossref

  81. Carvajal Irvith M., Sen Ranjan, Functional Analysis of the Murine TCRβ-Chain Gene Enhancer, The Journal of Immunology, 164, 12, 2000. Crossref

  82. Kundu Mondira, Chen Amy, Anderson Stacie, Kirby Martha, Xu LiPing, Castilla Lucio H., Bodine David, Liu Pu Paul, Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11, Blood, 100, 7, 2002. Crossref

  83. Ito Yoshiaki, Bae Suk-Chul, The Runt Domain Transcription Factor, PEBP2/CBF, and its Involvement in Human Leukemia, in Oncogenes as Transcriptional Regulators, 1997. Crossref

  84. GANLY PETER, WALKER LOGAN C, MORRIS CHRISTINE M, Familial Mutations of the Transcription Factor RUNX1 (AML1, CBFA2) Predispose to Acute Myeloid Leukemia, Leukemia & Lymphoma, 45, 1, 2004. Crossref

  85. Banerjee Chaitali, Javed Amjad, Choi Je-Yong, Green Jack, Rosen Vicki, van Wijnen André J., Stein Janet L., Lian Jane B., Stein Gary S., Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype, Endocrinology, 142, 9, 2001. Crossref

  86. Inoue Ken-ichi, Shiga Takashi, Ito Yoshiaki, Runx transcription factors in neuronal development, Neural Development, 3, 1, 2008. Crossref

  87. Tracey W.D., Pepling M.E., Horb M.E., Thomsen G.H., Gergen J.P., A Xenopus homologue of aml-1 reveals unexpected patterning mechanisms leading to the formation of embryonic blood, Development, 125, 8, 1998. Crossref

  88. Aronson B D, Fisher A L, Blechman K, Caudy M, Gergen J P, Groucho-dependent and -independent repression activities of Runt domain proteins, Molecular and Cellular Biology, 17, 9, 1997. Crossref

  89. Li L.H., Gergen J.P., Differential interactions between Brother proteins and Runt domain proteins in the Drosophila embryo and eye, Development, 126, 15, 1999. Crossref

  90. Kramer S.G., Jinks T.M., Schedl P., Gergen J.P., Direct activation of Sex-lethal transcription by the Drosophila runt protein, Development, 126, 1, 1999. Crossref

  91. Fisher Alfred L., Caudy Michael, Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates, Genes & Development, 12, 13, 1998. Crossref

  92. Rowley Janet D., THE CRITICAL ROLE OF CHROMOSOME TRANSLOCATIONS IN HUMAN LEUKEMIAS, Annual Review of Genetics, 32, 1, 1998. Crossref

  93. Crute Barbara E., Lewis Amy F., Wu Zining, Bushweller John H., Speck Nancy A., Biochemical and Biophysical Properties of the Core-binding Factor α2 (AML1) DNA-binding Domain, Journal of Biological Chemistry, 271, 42, 1996. Crossref

  94. Tang Lei, Guo Bo, Javed Amjad, Choi Je-Yong, Hiebert Scott, Lian Jane B., van Wijnen André J., Stein Janet L., Stein Gary S., Zhou G. Wayne, Crystal Structure of the Nuclear Matrix Targeting Signal of the Transcription Factor Acute Myelogenous Leukemia-1/Polyoma Enhancer-binding Protein 2αB/Core Binding Factor α2, Journal of Biological Chemistry, 274, 47, 1999. Crossref

  95. Gutiérrez José, Sierra José, Medina Ricardo, Puchi Marcia, Imschenetzky María, van Wijnen Andre, Lian Jane, Stein Gary, Stein Janet, Montecino Martin, Interaction of CBFα/AML/PEBP2α Transcription Factors with Nucleosomes Containing Promoter Sequences Requires Flexibility in the Translational Positioning of the Histone Octamer and Exposure of the CBFα Site, Biochemistry, 39, 44, 2000. Crossref

  96. Javed A., Guo B., Hiebert S., Choi J.Y., Green J., Zhao S.C., Osborne M.A., Stifani S., Stein J.L., Lian J.B., van Wijnen A.J., Stein G.S., Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription, Journal of Cell Science, 113, 12, 2000. Crossref

  97. Hanai Jun-ichi, Chen Lin Feng, Kanno Tomohiko, Ohtani-Fujita Naoko, Kim Woo Young, Guo Wei-Hui, Imamura Takeshi, Ishidou Yasuhiro, Fukuchi Minoru, Shi Meng-Jiao, Stavnezer Janet, Kawabata Masahiro, Miyazono Kohei, Ito Yoshiaki, Interaction and Functional Cooperation of PEBP2/CBF with Smads, Journal of Biological Chemistry, 274, 44, 1999. Crossref

  98. Pozner Amir, Goldenberg Dalia, Negreanu Varda, Le Shu-Yun, Elroy-Stein Orna, Levanon Ditsa, Groner Yoram, Transcription-Coupled Translation Control of AML1/RUNX1 Is Mediated by Cap- and Internal Ribosome Entry Site-Dependent Mechanisms, Molecular and Cellular Biology, 20, 7, 2000. Crossref

  99. Marshall Leslie J., Moore Amy C., Ohki Misao, Kitabayashi Issay, Patterson David, Ornelles David A., RUNX1 Permits E4orf6-Directed Nuclear Localization of the Adenovirus E1B-55K Protein and Associates with Centers of Viral DNA and RNA Synthesis, Journal of Virology, 82, 13, 2008. Crossref

  100. Akamatsu Yoshiko, Ohno Tetsuya, Hirota Kiichi, Kagoshima Hiroshi, Yodoi Junji, Shigesada Katsuya, Redox Regulation of the DNA Binding Activity in Transcription Factor PEBP2, Journal of Biological Chemistry, 272, 23, 1997. Crossref

  101. Zhang Yu-Wen, Yasui Natsuo, Ito Kosei, Huang Gang, Fujii Makiko, Hanai Jun-ichi, Nogami Hiroshi, Ochi Takahiro, Miyazono Kohei, Ito Yoshiaki, A RUNX2/PEBP2 αA/ CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia , Proceedings of the National Academy of Sciences, 97, 19, 2000. Crossref

  102. Hess Jochen, Porte Dominique, Munz Christine, Angel Peter, AP-1 and Cbfa/Runt Physically Interact and Regulate Parathyroid Hormone-dependent MMP13 Expression in Osteoblasts through a New Osteoblast-specific Element 2/AP-1 Composite Element, Journal of Biological Chemistry, 276, 23, 2001. Crossref

  103. Zhang Yu-Wen, Yasui Natsuo, Kakazu Naoki, Abe Tatsuo, Takada Kenzo, Imai Shosuke, Sato Motohiko, Nomura Shintaro, Ochi Takahiro, Okuzumi Shigeharu, Nogami Hiroshi, Nagai Toshiro, Ohashi Hirohumi, Ito Yoshiaki, PEBP2αA/CBFA1 mutations in Japanese cleidocranial dysplasia patients, Gene, 244, 1-2, 2000. Crossref

  104. Okuda Tsukasa, Takeda Kiyoshi, Fujita Yasuko, Nishimura Motohiro, Yagyu Shigeki, Yoshida Makie, Akira Shizuo, Downing James R., Abe Tatsuo, Biological Characteristics of the Leukemia-Associated Transcriptional Factor AML1 Disclosed by Hematopoietic Rescue of AML1 -Deficient Embryonic Stem Cells by Using a Knock-in Strategy , Molecular and Cellular Biology, 20, 1, 2000. Crossref

  105. Davis J Nathan, Williams B Jill, Herron Jeffrey T, Galiano Floyd J, Meyers Shari, ETO-2, a new member of the ETO-family of nuclear proteins, Oncogene, 18, 6, 1999. Crossref

  106. Zeng Congmei, McNeil Sandra, Pockwinse Shirwin, Nickerson Jeffrey, Shopland Lindsay, Lawrence Jeanne B., Penman Sheldon, Hiebert Scott, Lian Jane B., van Wijnen André J., Stein Janet L., Stein Gary S., Intranuclear targeting of AML/CBFα regulatory factors to nuclear matrix-associated transcriptional domains, Proceedings of the National Academy of Sciences, 95, 4, 1998. Crossref

  107. van der Reijden Bert A, Dauwerse Hans G, Giles Rachel H, Jagmohan-Changur Shantie, Wijmenga Cisca, Liu P Paul, Smit Bep, Wessels Hans W, Beverstock Geoff C, Jotterand-Bellomo Martine, Martinet Danielle, Mühlematter Dominique, Lafage-Pochitaloff Marina, Gabert Jean, Reiffers Josy, Bilhou-Nabera Chrystèle, Ommen Gert-Jan B van, Hagemeijer Anne, Breuning Martijn H, Genomic acute myeloid leukemia-associated inv(16)(p13q22) breakpoints are tightly clustered, Oncogene, 18, 2, 1999. Crossref

  108. Goetz Tamara L., Gu Ting-Lei, Speck Nancy A., Graves Barbara J., Auto-Inhibition of Ets-1 Is Counteracted by DNA Binding Cooperativity with Core-Binding Factor α2, Molecular and Cellular Biology, 20, 1, 2000. Crossref

  109. Gu Ting-Lei, Goetz Tamara L., Graves Barbara J., Speck Nancy A., Auto-Inhibition and Partner Proteins, Core-Binding Factor β (CBFβ) and Ets-1, Modulate DNA Binding by CBFα2 (AML1), Molecular and Cellular Biology, 20, 1, 2000. Crossref

  110. Kanno Yuka, Kanno Tomohiko, Sakakura Chohei, Bae Suk-Chul, Ito Yoshiaki, Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation, Molecular and Cellular Biology, 18, 7, 1998. Crossref

  111. Fujita Yasuko, Nishimura Motohiro, Taniwaki Masafumi, Abe Tatsuo, Okuda Tsukasa, Identification of an Alternatively Spliced Form of the Mouse AML1/RUNX1 Gene Transcript AML1c and Its Expression in Early Hematopoietic Development, Biochemical and Biophysical Research Communications, 281, 5, 2001. Crossref

  112. Stein Gary S, Lian Jane B, Wijnen Andre J van, Stein Janet L, Montecino Martin, Javed Amjad, Zaidi Sayyed K, Young Daniel W, Choi Je-Yong, Pockwinse Shirwin M, Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression, Oncogene, 23, 24, 2004. Crossref

  113. Jiménez Maria J. G., Balbín Milagros, López José M., Alvarez Jesús, Komori Toshihisa, López-Otín Carlos, Collagenase 3 Is a Target of Cbfa1, a Transcription Factor of the runt Gene Family Involved in Bone Formation , Molecular and Cellular Biology, 19, 6, 1999. Crossref

  114. Thirunavukkarasu Kannan, Mahajan Muktar, McLarren Keith W., Stifani Stefano, Karsenty Gerard, Two Domains Unique to Osteoblast-Specific Transcription Factor Osf2/Cbfa1 Contribute to Its Transactivation Function and Its Inability To Heterodimerize with Cbfβ, Molecular and Cellular Biology, 18, 7, 1998. Crossref

  115. Javed Amjad, Gutierrez Soraya, Montecino Martin, van Wijnen André J., Stein Janet L., Stein Gary S., Lian Jane B., Multiple Cbfa/AML Sites in the Rat Osteocalcin Promoter Are Required for Basal and Vitamin D-Responsive Transcription and Contribute to Chromatin Organization, Molecular and Cellular Biology, 19, 11, 1999. Crossref

  116. Ning Yang-Min, Robins Diane M., AML3/CBFα1 Is Required for Androgen-specific Activation of the Enhancer of the Mouse Sex-limited Protein (Slp) Gene, Journal of Biological Chemistry, 274, 43, 1999. Crossref

  117. Harada Hironori, Harada Yuka, O’Brien Darin P., Rice Dennis S., Naeve Clayton W., Downing James R., HERF1, a Novel Hematopoiesis-Specific RING Finger Protein, Is Required for Terminal Differentiation of Erythroid Cells, Molecular and Cellular Biology, 19, 5, 1999. Crossref

  118. Ducy Patricia, Schinke Thorsten, Karsenty Gerard, The Osteoblast: A Sophisticated Fibroblast under Central Surveillance, Science, 289, 5484, 2000. Crossref

  119. Odaka Yoshinobu, Mally Anirudh, Elliott Liza T, Meyers Shari, Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8), Oncogene, 19, 32, 2000. Crossref

  120. Svaren John, Ehrig Torsten, Abdulkadir Sarki A., Ehrengruber Markus U., Watson Mark A., Milbrandt Jeffrey, EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis, Journal of Biological Chemistry, 275, 49, 2000. Crossref

  121. Yamaguchi Yuko, Kurokawa Mineo, Imai Yoichi, Izutsu Koji, Asai Takashi, Ichikawa Motoshi, Yamamoto Go, Nitta Eriko, Yamagata Tetsuya, Sasaki Kazuki, Mitani Kinuko, Ogawa Seishi, Chiba Shigeru, Hirai Hisamaru, AML1 Is Functionally Regulated through p300-mediated Acetylation on Specific Lysine Residues, Journal of Biological Chemistry, 279, 15, 2004. Crossref

  122. Mao Shifeng, Frank Richard C., Zhang Jin, Miyazaki Yasushi, Nimer Stephen D., Functional and Physical Interactions between AML1 Proteins and an ETS Protein, MEF: Implications for the Pathogenesis of t(8;21)-Positive Leukemias, Molecular and Cellular Biology, 19, 5, 1999. Crossref

  123. Le Xiao-Feng, Groner Yoram, Kornblau Steve M., Gu Yun, Hittelman Walter N., Levanon Ditsa, Mehta Kapil, Arlinghaus Ralph B., Chang Kun-Sang, Regulation of AML2/CBFA3 in Hematopoietic Cells through the Retinoic Acid Receptor α-Dependent Signaling Pathway, Journal of Biological Chemistry, 274, 31, 1999. Crossref

  124. Kanno Tomohiko, Kanno Yuka, Chen Lin-Feng, Ogawa Eiko, Kim Woo-Young, Ito Yoshiaki, Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit, Molecular and Cellular Biology, 18, 5, 1998. Crossref

  125. Kohzaki Hidetsugu, Ito Kosei, Huang Gang, Wee Hee-Jun, Murakami Yota, Ito Yoshiaki, Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2, Oncogene, 18, 28, 1999. Crossref

  126. McNeil Sandra, Zeng Congmei, Harrington Kimberly S., Hiebert Scott, Lian Jane B., Stein Janet L., van Wijnen André J., Stein Gary S., The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFα2 transcription factor, Proceedings of the National Academy of Sciences, 96, 26, 1999. Crossref

  127. Kurosaka Hiroshi, Islam Md. Nurul, Kuremoto Koh-ichi, Hayano Satoru, Nakamura Masahiro, Kawanabe Noriaki, Yanagita Takeshi, Rice David P.C., Harada Hidemitsu, Taniuchi Ichiro, Yamashiro Takashi, Core Binding Factor Beta Functions in the Maintenance of Stem Cells and Orchestrates Continuous Proliferation and Differentiation in Mouse Incisors, Stem Cells, 29, 11, 2011. Crossref

  128. Look A. Thomas, Oncogenic Transcription Factors in the Human Acute Leukemias, Science, 278, 5340, 1997. Crossref

  129. Huang Xuemei, Crute Barbara E., Sun Chaohong, Tang Yen-Yee, Kelley John J., Lewis Amy F., Hartman Kari L., Laue Thomas M., Speck Nancy A., Bushweller John H., Overexpression, Purification, and Biophysical Characterization of the Heterodimerization Domain of the Core-binding Factor β Subunit, Journal of Biological Chemistry, 273, 4, 1998. Crossref

  130. Bae Suk-Chul, Lee Junho, cDNA cloning of run, a Caenorhabditis elegans Runt domain encoding gene, Gene, 241, 2, 2000. Crossref

  131. Levanon Ditsa, Goldstein Robert E., Bernstein Yael, Tang Hua, Goldenberg Dalia, Stifani Stefano, Paroush Ze’ev, Groner Yoram, Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors, Proceedings of the National Academy of Sciences, 95, 20, 1998. Crossref

  132. McLarren Keith W., Lo Rita, Grbavec Diane, Thirunavukkarasu Kannan, Karsenty Gerard, Stifani Stefano, The Mammalian Basic Helix Loop Helix Protein HES-1 Binds to and Modulates the Transactivating Function of the Runt-related Factor Cbfa1, Journal of Biological Chemistry, 275, 1, 2000. Crossref

  133. Shi Meng-Jiao, Stavnezer Janet, CBFα3 (AML2) Is Induced by TGF-β1 to Bind and Activate the Mouse Germline Ig α Promoter, The Journal of Immunology, 161, 12, 1998. Crossref

Zukünftige Artikel

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen Preise und Aborichtlinien Begell House Kontakt Language English 中文 Русский Português German French Spain