International Journal of Physiology and Pathophysiology
Erscheint 4 Ausgaben pro Jahr
ISSN Druckformat: 2155-014X
ISSN Online: 2155-0158
SJR:
0.116
Voltage-Gated Calcium Channels: Classification and Pharmacological Properties
Volumen 9,
Ausgabe 1, 2018,
pp. 85-97
DOI: 10.1615/IntJPhysPathophys.v9.i1.100
ABSTRAKT
Calcium influx though voltage-gated calcium channels mediates a huge number of physiological events and cellular responses. Numerous scientific reports indicate that calcium channels are involved in synaptic transmission, neurotransmitter release, regulation of gene expression, cellular membrane voltage oscillations, pacemaker activity, secretion of specific substances from nerve and secretory cells, morphological differentiation, activation of calcium-dependent enzymes, etc. This review represents physiological and pharmacological properties of voltage-gated calcium channels expressed in mammalian cells.
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