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Critical Reviews™ in Therapeutic Drug Carrier Systems

Published 6 issues per year

ISSN Print: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

Indexed in

Emerging Potential of Nanosuspension-Enabled Drug Delivery: An Overview

Volume 32, Issue 6, 2015, pp. 535-557
DOI: 10.1615/CritRevTherDrugCarrierSyst.2015012271
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ABSTRACT

Poor aqueous solubility is one of the key concerns of the majority of new drug molecules. One of the important problems associated with such drugs is that they often lead to low bioavailability. Researchers have used various techniques, but little success has been achieved due to poor stability and industrial viability, including technique cost. Of the numerous techniques, nanosuspensions (NSs) have drawn interest in improving solubility. NSs are dispersions of nanosized drug particles stabilized with the aid of appropriate agents. Stabilizers for NSs are generally recognized as safe (GRAS) excipients that can be chosen from a number of surfactants and/or polymers to food proteins. The commonly used techniques for preparation of NSs including top-down and bottom-up methods, along with new fabrication techniques based on supercritical (SC) fluids, are reviewed. This review also includes preparatory techniques, characterization, potential applications, and recent advancements in the field of NSs.

CITED BY
  1. Feng Xiaozhou, Liu Juanjuan, Fan Shuai, Liu Fan, Li Yadong, Jin Yuanyuan, Bai Liping, Yang Zhaoyong, The identification of goat peroxiredoxin-5 and the evaluation and enhancement of its stability by nanoparticle formation, Scientific Reports, 6, 1, 2016. Crossref

  2. Shah Sanket, Date Abhijit, Holm Renè, Strategies for the Formulation Development of Poorly Soluble Drugs via Oral Route, in Innovative Dosage Forms, 2019. Crossref

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