Published 6 issues per year
ISSN Print: 0278-940X
ISSN Online: 1943-619X
Indexed in
The State of Head Injury Biomechanics: Past, Present, and Future: Part 1
ABSTRACT
This article is the first of two parts of a comprehensive survey of the biomechanics of head injury since its inception in 1939 in the United States, the separation being made for temporal and spatial reasons. The second portion of this material will be published at a later time in this journal. The discussion will be almost exclusively limited to nonpenetrating events. The topics presented in the following sections include an introduction that discusses the magnitude of the problem, the basic tools of biomechanics, and significant major reference sources covering this subject. This is succeeded by a brief description of the components of the head, classification of head injuries, early experimental investigations and human tolerance considerations, measurement techniques of kinetic parameters, and head motion and head injury investigations prior to 1966. A Head Injury Conference sponsored by the National Institutes of Neurological Diseases and Stroke in 1966 changed the landscape of investigations in this area. While informal collaboration between neurosurgeons and engineers had existed prior to this time, the conference established a permanent mechanism ofsynergism between these disciplines, produced the first zero-order realistic model of biomechanical head injury investigation, and established a 4-year program of federally funded research into the mechanical properties of the tissues of the cranium. While a recession precluded a continuation of the national sponsorship of such work, this 4-year period of intensive research resulted in a nationwide individual effort to develop further knowledge in this area. The current presentation, then, covers the mechanical and structural properties of solid and fluid tissues of the head, emphasizing progress during the past 3 decades; fetal cranial properties; analytical and numerical head injury models; experimental cranial loads applied to human volunteers and cadaver heads, dynamic loading of surrogate heads; and, finally, head injury mechanisms. The future publication will encompass experimental, analytical, and some numerical and regulatory information and that will be divided into the following sections:
- head injury experimentation involving translatory and rotational motion: equipment, subjects and mechanical and physiological consequences
- diffuse axonal injury: production and traumatic effects; mechanical properties at the axonal and neuronal level
- vehicular crash investigation and simulation: reconstruction methodologies, staging, surrogate validation, and occupant protection, including vehicular design
- injury thresholds and tolerances, including skull and vessel failure and brain and brainstem damage, including consideration of loading directions
- criteria for head injury: governmental and industry regulations, including effects of combined motion- and tissue-level loading
- further discussions of cranial component properties and injury mechanisms
- sports head injury considerations: boxing, baseball, softball, football, ice hockey, and skiing activities; protective head devices for these activities
- vehicular protective devices: design, efficacy, standards, and limitations; models for helmets and experimental validation
This presentation is based on my nearly 4 decades of head injury research, continuous collaboration and discussions with prominent members of the neurosurgical and orthopedic community, and an exhaustive, 2-year search of the literature. While every effort has been made to include all relevant information, it is inevitable that some important research has not come to my attention, and I apologize for any such omissions.
It is hoped that this survey will serve as a resource for researchers and practitioners in the area of traumatic head injury and provide a roadmap for further investigations that are urgently needed. For example, this could include a determination of the rate of absorption of blood emitted from broken vessels, and, hopefully, some correlation between mechanical failure and physiological dysfunction of the various relevant tissues of the head. Although a good beginning has been initiated, additional information at the neuronal and axonal level concerning the effect of loading on function as well as age-related changes in geometry and tissue properties is also needed.
-
Goldsmith Werner, Plunkett John, A Biomechanical Analysis of the Causes of Traumatic Brain Injury in Infants and Children, American Journal of Forensic Medicine & Pathology, 25, 2, 2004. Crossref
-
Long James, Yang James, Lei Zhipeng, Liang Daan, Simulation-based assessment for construction helmets, Computer Methods in Biomechanics and Biomedical Engineering, 18, 1, 2015. Crossref
-
Leestma Jan, Thibault Kirk, Physical Injury to the Nervous System, in Forensic Neuropathology, Third Edition, 2014. Crossref
-
Ivancevic Vladimir G., New mechanics of traumatic brain injury, Cognitive Neurodynamics, 3, 3, 2009. Crossref
-
Young G Bryan, Traumatic brain injury: The continued quest for early prognostic determination*, Critical Care Medicine, 38, 1, 2010. Crossref
-
Goriely Alain, Geers Marc G. D., Holzapfel Gerhard A., Jayamohan Jayaratnam, Jérusalem Antoine, Sivaloganathan Sivabal, Squier Waney, van Dommelen Johannes A. W., Waters Sarah, Kuhl Ellen, Mechanics of the brain: perspectives, challenges, and opportunities, Biomechanics and Modeling in Mechanobiology, 14, 5, 2015. Crossref
-
Liang Zhaoyang, Luo Yunhua, A QCT-Based Nonsegmentation Finite Element Head Model for Studying Traumatic Brain Injury, Applied Bionics and Biomechanics, 2015, 2015. Crossref
-
Wennberg Richard A., Cohen Howard B., Walker Stephanie R., Neurologic Injuries in Hockey, Neurologic Clinics, 26, 1, 2008. Crossref
-
Yunhua Luo , Zhaoyang Liang , Sport helmet design and virtual impact test by image-based finite element modeling, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013. Crossref
-
Hong Y., Sarntinoranont M., Subhash G., Canchi S., King M. A., Localized Tissue Surrogate Deformation due to Controlled Single Bubble Cavitation, Experimental Mechanics, 56, 1, 2016. Crossref
-
Franceschini G., Bigoni D., Regitnig P., Holzapfel G.A., Brain tissue deforms similarly to filled elastomers and follows consolidation theory, Journal of the Mechanics and Physics of Solids, 54, 12, 2006. Crossref
-
Li X.Y., Li J., Feng D.F., Gu L., Diffuse axonal injury induced by simultaneous moderate linear and angular head accelerations in rats, Neuroscience, 169, 1, 2010. Crossref
-
Brennen Christopher Earls, Cavitation in medicine, Interface Focus, 5, 5, 2015. Crossref
-
Breedlove Evan L., Robinson Meghan, Talavage Thomas M., Morigaki Katherine E., Yoruk Umit, O'Keefe Kyle, King Jeff, Leverenz Larry J., Gilger Jeffrey W., Nauman Eric A., Biomechanical correlates of symptomatic and asymptomatic neurophysiological impairment in high school football, Journal of Biomechanics, 45, 7, 2012. Crossref
-
Meaney David F., Olvey Stephen E., Gennarelli Thomas A., Biomechanical Basis of Traumatic Brain Injury, in Youmans Neurological Surgery, 2011. Crossref
-
Drapaca Corina S., An electromechanical model of neuronal dynamics using Hamilton's principle, Frontiers in Cellular Neuroscience, 9, 2015. Crossref
-
Wennberg Richard A., Cohen Howard B., Walker Stephanie R., Neurologic Injuries in Hockey, Physical Medicine and Rehabilitation Clinics of North America, 20, 1, 2009. Crossref
-
Evans D., Drapaca C., Cusumano J. P., A Mechano-Hydraulic Model of Intracranial Pressure Dynamics, in Mechanics of Biological Systems and Materials, Volume 6, 2017. Crossref
-
Mukerji N., Soh C., Mitchell P., In-vivomeasurement of brain relaxation after lobectomies, British Journal of Neurosurgery, 20, 3, 2006. Crossref
-
Evans D., Drapaca C., Cusumano J. P., Dynamics and Bifurcations in Low-Dimensional Models of Intracranial Pressure, in Mathematical and Computational Approaches in Advancing Modern Science and Engineering, 2016. Crossref
-
Kumaria A., Tolias C. M., In vitromodels of neurotrauma, British Journal of Neurosurgery, 22, 2, 2008. Crossref
-
Drapaca Corina, Fractional calculus in neuronal electromechanics, Journal of Mechanics of Materials and Structures, 12, 1, 2017. Crossref
-
Li Y.Q., Gao X.-L., Horner S.E., Zheng J.Q., Analytical models for the impact of a solid sphere on a fluid-filled spherical shell incorporating the stress wave propagation effect and their applications to blunt head impacts, International Journal of Mechanical Sciences, 130, 2017. Crossref
-
Luo Yunhua, Li Zhaoxia, Chen Hongxi, Finite-element study of cerebrospinal fluid in mitigating closed head injuries, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 226, 7, 2012. Crossref
-
King Albert I., Head Injury Research: Experimental Studies, in The Biomechanics of Impact Injury, 2018. Crossref
-
Luo Yunhua, Liang Zhaoyang, Understanding how a sport-helmet protects the head from closed injury by virtual impact tests, Bio-Medical Materials and Engineering, 28, 3, 2017. Crossref
-
Pittella José Eymard Homem, Gusmão Sebastião Nataniel da Silva, The conformation of the brain plays an important role in the distribution of diffuse axonal injury in fatal road traffic accident, Arquivos de Neuro-Psiquiatria, 62, 2b, 2004. Crossref
-
Yu Zhe, Morrison Barclay, Experimental Mild Traumatic Brain Injury Induces Functional Alteration of the Developing Hippocampus, Journal of Neurophysiology, 103, 1, 2010. Crossref
-
Cernak Ibolja, Vink Robert, Zapple David N., Cruz Maria I., Ahmed Farid, Chang Taeun, Fricke Stanley T., Faden Alan I., The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats, Neurobiology of Disease, 17, 1, 2004. Crossref
-
Drapaca Corina, Sivaloganathan Siv, Modeling Traumatic Brain Injuries, Aneurysms, and Strokes, in Mathematical Modelling and Biomechanics of the Brain, 37, 2019. Crossref
-
Cummiskey Brian, Sankaran Goutham N, McIver Kevin G, Shyu Daniel, Markel Justin, Talavage Thomas M, Leverenz Larry, Meyer Janette J, Adams Douglas, Nauman Eric A, Quantitative evaluation of impact attenuation by football helmets using a modal impulse hammer, Proceedings of the Institution of Mechanical Engineers, Part P: Journal of Sports Engineering and Technology, 233, 2, 2019. Crossref
-
Eliasson Veronica, Koumlis Stylianos, Traumatic Brain Injury: Models and Mechanisms of Traumatic Brain Injury, in Biomechanical Principles and Applications in Sports, 2019. Crossref
-
Eliasson Veronica, Koumlis Stylianos, Traumatic Brain Injury: Introduction to Anatomy of the Human Head and Basic Mechanical Principles, in Biomechanical Principles and Applications in Sports, 2019. Crossref
-
Kendall Marshall, Anna Oeur , Brien Susan E, Cusimano Michael, Marshall Shawn, Gilchrist Michael D, Hoshizaki Thomas B, Accident reconstructions of falls, collisions, and punches in sports, Journal of Concussion, 4, 2020. Crossref
-
McNamara Eileen H., Grillakis Antigone A., Tucker Laura B., McCabe Joseph T., The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: A status report, Experimental Neurology, 333, 2020. Crossref
-
Tan X. Gary, Sajja Venkata Siva Sai Sujith, D’Souza Maria M., Gupta Raj K., Long Joseph B., Singh Ajay K., Bagchi Amit, A Methodology to Compare Biomechanical Simulations With Clinical Brain Imaging Analysis Utilizing Two Blunt Impact Cases, Frontiers in Bioengineering and Biotechnology, 9, 2021. Crossref
-
Kim Chunghwan, Choi Won June, Ng Yisha, Kang Wonmo, Mechanically Induced Cavitation in Biological Systems, Life, 11, 6, 2021. Crossref
-
Berger Stanley A., King Albert I., Lewis Jack L., Werner Goldsmith: Life and Work (1924–2003), Annual Review of Biomedical Engineering, 7, 1, 2005. Crossref
-
Li Yongqiang, Fan Hualin, Gao Xin-Lin, Ballistic helmets: Recent advances in materials, protection mechanisms, performance, and head injury mitigation, Composites Part B: Engineering, 238, 2022. Crossref
-
Kennedy Karen A.M., Ostrakhovitch Elena A., Sandiford Shelley D.E., Dayarathna Thamara, Xie Xiaojun, Waese Elaine Y.L., Chang Wing Y., Feng Qingping, Skerjanc Ilona S., Stanford William L., Li Shawn S.C., Mammalian Numb-interacting Protein 1/Dual Oxidase Maturation Factor 1 Directs Neuronal Fate in Stem Cells, Journal of Biological Chemistry, 285, 23, 2010. Crossref
-
Margulies Susan S., Coats Brittany, Biomechanics of pediatric TBI, in Pediatric Traumatic Brain Injury, 2010. Crossref
-
Ghuman Harmanvir, Mauney Carrinton, Donnelly Julia, Massensini Andre R., Badylak Stephen F., Modo Michel, Biodegradation of ECM hydrogel promotes endogenous brain tissue restoration in a rat model of stroke, Acta Biomaterialia, 80, 2018. Crossref
-
Ghuman Harmanvir, Gerwig Madeline, Nicholls Francesca J., Liu Jessie R., Donnelly Julia, Badylak Stephen F., Modo Michel, Long-term retention of ECM hydrogel after implantation into a sub-acute stroke cavity reduces lesion volume, Acta Biomaterialia, 63, 2017. Crossref
-
Alfasi Abdulghader M., Shulyakov Alexander V., Del Bigio Marc R., Intracranial biomechanics following cortical contusion in live rats, Journal of Neurosurgery, 119, 5, 2013. Crossref