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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats

Volume 21, Issue 1, 2019, pp. 79-88
DOI: 10.1615/IntJMedMushrooms.2018029348
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ABSTRACT

Recent interest in diet-induced modulation of the gut microbiome has led to research on the impact that dietary fibers can have on host health. Lentinus edodes mushroom-derived fibers may act as an appropriate substrate for gut microbe digestion and metabolism. The metabolites that gut microbes excrete can modulate host energy balance, gut absorption, appetite, and lipid metabolism. In the present study, we explored the dynamics of the gut microbiome of hypercholesterolemic rats supplemented with L. edodes. Wistar rats were offered a chow maintenance diet (CMD; CON group) or the same CMD ration with cholesterol (1.5% w/w) and cholic acid (0.5% w/w) added to induce hypercholesterolemia (day 1 to day 24). Hypercholesterolemic rats were subsequently offered either the same cholesterol-cholic acid diet (HC-CON group) or were supplemented with L. edodes (5% w/w; LE group) for 42 days (day 25 to day 66). At the end of the experiment, serum triglycerides, total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol concentrations were determined. Colon digesta were subjected to DNA extraction and subsequent 16S rRNA gene sequencing. Raw sequences were quality filtered and statistically analyzed using QIIME and LEfSe tools. Triglyceride concentrations were lower (P = 0.002) in the LE group than in the CON and HC-CON groups. Total cholesterol and LDL cholesterol concentrations were slightly decreased, whereas HDL cholesterol concentrations were increased by L. edodes supplementation compared with the HC-CON group. The gut microbiome of the LE group had higher species richness characterized by increased abundance of Clostridium and Bacteroides spp. Linear discriminant analysis identified bacterial clades that were statistically different among treatment groups. In conclusion, manipulation of gut microbiota through the administration of L. edodes could manage dyslipidemia.

CITED BY
  1. Sohail Muhammad U., Elrayess Mohamed A., Al Thani Asma A., Al-Asmakh Maha, Yassine Hadi M., Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar, Microorganisms, 7, 12, 2019. Crossref

  2. Spim Sara Rosicler Vieira, Castanho Nathalia Roberta Cardoso Mendes, Pistila Ana Maria Holtz, Jozala Angela Faustino, Oliveira Júnior José Martins, Grotto Denise, Lentinula edodes mushroom as an ingredient to enhance the nutritional and functional properties of cereal bars, Journal of Food Science and Technology, 58, 4, 2021. Crossref

  3. Lindenwald Dimitri Leonid, Lepenies Bernd, C-Type Lectins in Veterinary Species: Recent Advancements and Applications, International Journal of Molecular Sciences, 21, 14, 2020. Crossref

  4. Khursheed Rubiya, Singh Sachin Kumar, Wadhwa Sheetu, Gulati Monica, Awasthi Ankit, Therapeutic potential of mushrooms in diabetes mellitus: Role of polysaccharides, International Journal of Biological Macromolecules, 164, 2020. Crossref

  5. Yadav Divya, Negi Pradeep Singh, Bioactive components of mushrooms: Processing effects and health benefits, Food Research International, 148, 2021. Crossref

  6. Li Miaoyu, Yu Leilei, Zhao Jianxin, Zhang Hao, Chen Wei, Zhai Qixiao, Tian Fengwei, Role of dietary edible mushrooms in the modulation of gut microbiota, Journal of Functional Foods, 83, 2021. Crossref

  7. Sohail Muhammad U, Hedin Lars, Al-Asmakh Maha, Dysbiosis of the Salivary Microbiome is Associated with Hypertension and Correlated with Metabolic Syndrome Biomarkers, Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume 14, 2021. Crossref

  8. Anwar Haseeb, Hussain Ghulam, Rasul Azhar, Ali Shah Syed Muhammad, Naqvi Syed Ali Raza, Bukhari Shazia Anwer, Sohail Muhammad Umar, Faisal Muhammad Naeem, Mustafa Imtiaz, Munir Naveed, Nisar Jaweria, Shaukat Arslaan, Muzaffer Humaira, Potential role of probiotic species in ameliorating oxidative stress, effect on liver profile and hormones in male albino rat model, European Journal of Inflammation, 19, 2021. Crossref

  9. Al-Asmakh Maha, Sohail Muhammad Umar, Al-Jamal Ola, Shoair Banan Mosaad, Al-Baniali Asmaa Yousef, Bouabidi Salma, Nasr Shahd, Bawadi Hiba, The Effects of Gum Acacia on the Composition of the Gut Microbiome and Plasma Levels of Short-Chain Fatty Acids in a Rat Model of Chronic Kidney Disease, Frontiers in Pharmacology, 11, 2020. Crossref

  10. Mustafa Imtiaz, Anwar Haseeb, Irfan Shahzad, Muzaffar Humaira, Ijaz Muhammad Umar, Attenuation of carbohydrate metabolism and lipid profile by methanolic extract of Euphorbia helioscopia and improvement of beta cell function in a type 2 diabetic rat model, BMC Complementary Medicine and Therapies, 22, 1, 2022. Crossref

  11. Soroko Maria, Górniak Wanda, Zielińska Paulina, Górniak Aleksander, Śniegucka Karolina, Nawrot Karolina, Korczyński Mariusz, Effect of Lentinula edodes on Morphological and Biochemical Blood Parameters of Horses, Animals, 12, 9, 2022. Crossref

  12. Soroko-Dubrovina Maria, Górniak Wanda, Zielińska Paulina, Górniak Aleksander, Čebulj-Kadunc Nina, Korczyński Mariusz, Evaluation of Shiitake Mushroom (Lentinula edodes) Supplementation on the Blood Parameters of Young Thoroughbred Racehorses, Animals, 12, 22, 2022. Crossref

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