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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antitumor and Immunomodulating Activities of Exopolysaccharide Produced by Big Cup Culinary- Medicinal Mushroom Clitocybe maxima (Higher Basidiomycetes) in Liquid Submerged Culture

Volume 17, Issue 9, 2015, pp. 891-901
DOI: 10.1615/IntJMedMushrooms.v17.i9.90
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ABSTRACT

Water-soluble polysaccharides extracted from mushrooms have been found to have some physiological effects. In this study, exopolysaccharides (EPSs) were extracted by alcohol precipitation from cultivated broth of the mushroom Clitocybe maxima. EPSs with molecular weights of 104 and 105 Da were obtained by ultrafiltration; they are referred to as EPA and EPB, respectively. The major components of these EPSs were glucose, galactose, mannose, rhamnose, and arabinose. ICR mice with artificially induced metastatic pulmonary tumors were fed a daily diet containing EPA or EPB at doses of 8, 20, or 50 mg/kg. Results showed that the proliferation of pulmonary sarcoma lesions was lower in the groups fed EPS. In addition, the numbers of total T cells, CD4+ cells, CD8+ cells, and macrophages significantly increased in EPS-fed mice compared with the negative control group. The antitumor and immunomodulating effects observed in the EPB-fed groups were higher than those of EPA-fed groups. These results demonstrate the ability of EPSs of C. maxima to inhibit tumor cells while enhancing immune response.

CITED BY
  1. Lima Cristiane U.J.O., Gris Eliana F., Karnikowski Margô G.O., Antimicrobial properties of the mushroom Agaricus blazei – integrative review, Revista Brasileira de Farmacognosia, 26, 6, 2016. Crossref

  2. Friedman Mendel, Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans, Foods, 5, 4, 2016. Crossref

  3. Yu Zhidan, Song Ge, Liu Jing, Wang Jiayue, Zhang Pengying, Chen Kaoshan, Beneficial effects of extracellular polysaccharide from Rhizopus nigricans on the intestinal immunity of colorectal cancer mice, International Journal of Biological Macromolecules, 115, 2018. Crossref

  4. Ramesh Sindhu, Majrashi Mohammed, Almaghrabi Mohammed, Govindarajulu Manoj, Fahoury Eddie, Fadan Maali, Buabeid Manal, Deruiter Jack, Clark Randall, Mulabagal Vanisree, Agrawal Dinesh Chandra, Moore Timothy, Dhanasekaran Muralikrishnan, Overview of Therapeutic Efficacy of Mushrooms, in Medicinal Mushrooms, 2019. Crossref

  5. Song Ge, Zhou Nan, Lu Yan, Yu Zhidan, Chen Kaoshan, Zhang Pengying, The anti-gastritis activity of an exopolysaccharide from Rhizopus nigricans, Food Bioscience, 29, 2019. Crossref

  6. Chen Qi, Li Meng-shuang, Ding Wei, Tao Ming-min, Li Meng-ru, Qi Qi, Li Yu-huan, Li Juan, Zhang Liang, Effects of high N2/CO2 in package treatment on polyamine-derived 4-Aminobutyrate (GABA) biosynthesis in cold-stored white mushrooms (Agaricus bisporus), Postharvest Biology and Technology, 162, 2020. Crossref

  7. Chun Sechul, Gopal Judy, Muthu Manikandan, Antioxidant Activity of Mushroom Extracts/Polysaccharides—Their Antiviral Properties and Plausible AntiCOVID-19 Properties, Antioxidants, 10, 12, 2021. Crossref

  8. Guo Dongdong, Lei Jiayu, Xu Lijing, Cheng Yanfen, Feng Cuiping, Meng Junlong, Chang Mingchang, Geng Xueran, Two Novel Polysaccharides From Clitocybe squamulosa: Their Isolation, Structures, and Bioactivities, Frontiers in Nutrition, 9, 2022. Crossref

  9. Shin Hyun Young, Kim Hoon, Jeong Eun-Jin, Kim Hyun-Gyeong, Shin Jung-Cheul, Choi Sang-Young, Suh Hyung Joo, Moon Sung-Kwon, Yu Kwang-Won, Immunostimulatory Polysaccharide Fractionated from a Liquid Culture by Phellinus linteus Mycelium, Journal of the Korean Society of Food Science and Nutrition, 51, 1, 2022. Crossref

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