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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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MT-α-Glucan from the Fruit Body of the Maitake Medicinal Mushroom Grifola frondosa (Higher Basidiomyetes) Shows Protective Effects for Hypoglycemic Pancreatic β-Cells

Volume 15, Issue 4, 2013, pp. 373-381
DOI: 10.1615/IntJMedMushr.v15.i4.50
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ABSTRACT

The hypoglycemic effect of an α-glucan (designated here as MT-α-glucan) from the fruit body of the Maitake medicinal mushroom, Grifola frondosa, on a murine type 2 diabetes mellitus (T2DM) model was evaluated. Body weight and levels of fasting plasma glucose, glycosylated hemoglobin, triglycerides, cholesterol, free fatty acid, nitric oxide (NO), NO synthase, inducible NO synthase, and hepatic malondialdehyde content decreased significantly when MT-α-glucan was administered to T2DM mice. The content of serum insulin, hepatic glycogen, and reduced glutathione and the activity of superoxide dismutase and glutathione peroxidase increased significantly when MT-α-glucan was administered to T2DM mice. Histopathological changes of the pancreas were ameliorated in the treatment group. These data suggest that MT-α-glucan has a hypoglycemic effect on T2DM mice, which might be related to its protective effect of pancreatic β-cells exerted by decreasing levels of factors that destroy β-cells, such as oxidative stress and NO synthesis.

CITED BY
  1. Rahman Mohammad Azizur, Abdullah Noorlidah, Aminudin Norhaniza, Inhibitory Effect onIn VitroLDL Oxidation and HMG Co-A Reductase Activity of the Liquid-Liquid Partitioned Fractions ofHericium erinaceus(Bull.) Persoon (Lion’s Mane Mushroom), BioMed Research International, 2014, 2014. Crossref

  2. Wu Jianjun, Shi Songshan, Wang Huijun, Wang Shunchun, Mechanisms underlying the effect of polysaccharides in the treatment of type 2 diabetes: A review, Carbohydrate Polymers, 144, 2016. Crossref

  3. Islam Md. Asiful, Alam Fahmida, Solayman Md., Khalil Md. Ibrahim, Kamal Mohammad Amjad, Gan Siew Hua, Dietary Phytochemicals: Natural Swords Combating Inflammation and Oxidation-Mediated Degenerative Diseases, Oxidative Medicine and Cellular Longevity, 2016, 2016. Crossref

  4. Friedman Mendel, Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans, Foods, 5, 4, 2016. Crossref

  5. Zhao Chao, Yang Chengfeng, Wai Sydney Tang Chi, Zhang Yanbo, P. Portillo Maria, Paoli Paolo, Wu Yijing, San Cheang Wai, Liu Bin, Carpéné Christian, Xiao Jianbo, Cao Hui, Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus, Critical Reviews in Food Science and Nutrition, 59, 6, 2019. Crossref

  6. Turło Jadwiga, The biotechnology of higher fungi - current state and perspectives, Folia Biologica et Oecologica, 10, 2014. Crossref

  7. Morales Diego, Rutckeviski Renata, Villalva Marisol, Abreu Hellen, Soler-Rivas Cristina, Santoyo Susana, Iacomini Marcello, Smiderle Fhernanda Ribeiro, Isolation and comparison of α- and β-D-glucans from shiitake mushrooms (Lentinula edodes) with different biological activities, Carbohydrate Polymers, 229, 2020. Crossref

  8. Zhang Min, Yun Liyuan, Effects of Polysaccharides on Reducing Blood Glucose Based on Gut Microbiota Alteration, in Structure and Health Effects of Natural Products on Diabetes Mellitus, 2021. Crossref

  9. Arunachalam Karuppusamy, Sreeja Puthanpura Sasidharan, Yang Xuefei, The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance, Frontiers in Pharmacology, 13, 2022. Crossref

  10. Das Somenath, Prakash Bhanu, Edible mushrooms: Nutritional composition and medicinal benefits for improvement in quality life, in Research and Technological Advances in Food Science, 2022. Crossref

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