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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Immunomodulatory Effect of Polysaccharides Extracted from the Medicinal Mushroom Antrodia camphorata (Higher Basidiomycetes) in Specific Pathogen-Free Chickens

Volume 16, Issue 1, 2014, pp. 95-103
DOI: 10.1615/IntJMedMushr.v16.i1.90
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ABSTRACT

The immunomodulatory effect of polysaccharides extracted from mycelia of the medicinal mushroom Antrodia camphorata in submerged culture was studied in 100 specific pathogen-free (SPF) chickens. The chickens were randomly divided into 2 groups (50 per group). For the treated group, each kilogram of SPF chickens was fed 5 mg of A. camphorata extract (ACE) for 35 consecutive days. Chickens were killed on days 7, 14, 21, 28, and 35, and lymphocytes were separated from the blood, spleen, thymus, bursa, kidney, and pancreas of the chickens. The results showed that, compared to the control group, the immune organ indices (except for the thymus) were higher after 14 days (P < 0.05), and the contents of globulin in blood were significantly increased on the 21st day (P < 0.05). The most of biochemical indices did not significantly changed within 35 days of treatment. Moreover, the response of proliferation and the rates of positive T lymphocytes in blood were higher than in the control group (P < 0.05).The results presented herein indicate that ACE could enhance the immune functions of the organs in SPF chickens and could be an attractive application of nutraceuticals and pharmaceuticals.

CITED BY
  1. Zheng Junping, Jiao Siming, Li Qiongyu, Jia Peiyuan, Yin Heng, Zhao Xiaoming, Du Yuguang, Liu Hongtao, Antrodia cinnamomea Oligosaccharides Suppress Lipopolysaccharide-Induced Inflammation through Promoting O-GlcNAcylation and Repressing p38/Akt Phosphorylation, Molecules, 23, 1, 2017. Crossref

  2. Zhang Yutian, Wang Zhuo, Li Diying, Zang Wanting, Zhu Hai, Wu Pengyu, Mei Yuxia, Liang Yunxiang, A polysaccharide from Antrodia cinnamomea mycelia exerts antitumor activity through blocking of TOP1/TDP1-mediated DNA repair pathway, International Journal of Biological Macromolecules, 120, 2018. Crossref

  3. Wang Caicheng, Zhang Weiwei, Wong Jack Ho, Ng Tzibun, Ye Xiujuan, Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata, Applied Microbiology and Biotechnology, 103, 19, 2019. Crossref

  4. Chen Wan-Jing, Chang Fung-Wei, A Pilot Study to Assess Food Safety and Potential Cholesterol-Lowering Efficacy of Antrodia cinnamomea Solid-State Cultivated Mycelium in Healthy Adults, Evidence-Based Complementary and Alternative Medicine, 2020, 2020. Crossref

  5. Chung Yuan‑Chiang, Tzeng Chung‑Yuh, Chen Ying‑I, Chang Shu‑Wei, Hsu Tai‑Hao, Ho Wai‑Jane, Kuo Yueh‑Hsiung, Hung Pei‑Hsiu, Chang Shih‑Liang, Improving insulin resistance with Antrodia cinnamomea mycelium powder to induce a hypoglycemic effect in dexamethasone‑induced insulin‑resistant rats, Molecular Medicine Reports, 2017. Crossref

  6. Chen Yun-Yu, Lo Chiu-Ping, Lin Chin-Chung, Hsieh Yi-Hsuan, Effects of Taiwanofungus camphoratus on non-specific and specific immune activities in mice, Mycology, 9, 2, 2018. Crossref

  7. Kothari Damini, Patel Seema, Kim Soo-Ki, Anticancer and other therapeutic relevance of mushroom polysaccharides: A holistic appraisal, Biomedicine & Pharmacotherapy, 105, 2018. Crossref

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