Library Subscription: Guest
International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy

Volume 20, Issue 11, 2018, pp. 1047-1063
DOI: 10.1615/IntJMedMushrooms.2018028595
Get accessGet access

ABSTRACT

Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radical scavenging activity and antimicrobial and anticancer potential of methanol extracts of F. pinicola from central Italy. Molecular identification confirmed that the samples were F. pinicola; a Basic Local Alignment Search Tool search showed a close match (99% sequence identity) with European isolates of this species. The free radical scavenging capacities, measured by DPPH assay, showed that the extract activity was 3.5% that of Trolox. The MTT test, evaluated after 72 hours of treatment with increasing doses of extract (5-500 μg · mL-1), considerably inhibited proliferation in a dose-dependent manner in 2 human tumor cell lines. This reduction was coupled with a relevant induction of apoptosis in the human leukemia THP-1 cell line after 24 hours of treatment, but a relevant toxic effect occurred in the human colon adenocarcinoma HT29 cell line. The genotoxic potential of the methanol extracts was studied by single-cell gel electrophoresis of normal human leukocytes exposed to 20 μg extract at 37°C for 30 minutes; no DNA damage was observed. The F. pinicola methanol extract was found to have varying degrees of antifungal effects against the pathogenic fungi tested (minimum inhibitory concentration from 23.63 to 66.81 μg · mL-1). The results show that the tested F. pinicola extract has strong antimicrobial and chemo-preventive activities, but is a poor antioxidant.

CITED BY
  1. Venanzoni Roberto, Bini Enrico, Bricchi Emma, Angelini Paola, Contribution to the knowledge of fungal diversity of the Marmore Waterfalls (Umbria, central Italy), Italian Botanist, 7, 2019. Crossref

  2. Angelini Paola, Girometta Carolina, Tirillini Bruno, Moretti Simone, Covino Stefano, Cipriani Melania, D’Ellena Eleonora, Angeles Giancarlo, Federici Ermanno, Savino Elena, Cruciani Gabriele, Venanzoni Roberto, A comparative study of the antimicrobial and antioxidant activities of Inonotus hispidus fruit and their mycelia extracts, International Journal of Food Properties, 22, 1, 2019. Crossref

  3. Angelini Paola, Venanzoni Roberto, Angeles Flores Giancarlo, Tirillini Bruno, Orlando Giustino, Recinella Lucia, Chiavaroli Annalisa, Brunetti Luigi, Leone Sheila, Di Simone Simonetta Cristina, Ciferri Maria Chiara, Zengin Gokhan, Ak Gunes, Menghini Luigi, Ferrante Claudio, Evaluation of Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Extracts from Tricholosporum goniospermum, an Edible Wild Mushroom, Antibiotics, 9, 8, 2020. Crossref

  4. Angelini Paola, Matei Florentina, Flores Giancarlo Angeles, Pellegrino Roberto Maria, Vuguziga Lydie, Venanzoni Roberto, Tirillini Bruno, Emiliani Carla, Orlando Giustino, Menghini Luigi, Ferrante Claudio, Metabolomic Profiling, Antioxidant and Antimicrobial Activity of Bidens pilosa, Processes, 9, 6, 2021. Crossref

  5. Kurchenko V., Sushinskaya N., Maiorava K., Tarun E., Kiseleva I., Biologically Active Substances of Extracts from Various Wood-Decay Fungi and Their Antioxidant Activity, in Intelligent Biotechnologies of Natural and Synthetic Biologically Active Substances, 408, 2022. Crossref

  6. Angelini Paola, Girometta Carolina Elena, Venanzoni Roberto, Bertuzzi Gianluigi, Anti-Aging Properties of Medicinal Mushrooms in Systemic Aesthetic Medicine, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref

1633 Article views 33 Article downloads Metrics
1633 VIEWS 33 DOWNLOADS 6 Crossref CITATIONS Google
Scholar
CITATIONS

Articles with similar content:

Submerged Cultured Mycelium Extracts of Higher Basidiomycetes Mushrooms Selectively Inhibit Proliferation and Induce Differentiation of K562 Human Chronic Myelogenous Leukemia Cells International Journal of Medicinal Mushrooms, Vol.5, 2003, issue 3
Majed Yassin, Jamal A. Mahajna
Antiproliferative Activity and Cytotoxicity of Some Medicinal Wood-Destroying Mushrooms from Russia International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 1
Cesar Espinoza, Alla V. Shnyreva, Ángel Trigos, José M. Padrón, Anastasia A. Shnyreva
Biological Activities of Different Strains of the Genus Ganoderma spp. (Agaricomycetes) from Mexico International Journal of Medicinal Mushrooms, Vol.23, 2021, issue 2
Alla V. Shnyreva, Ángel Trigos, Victoria Espinosa-García, José M. Padrón, Guillermo Mendoza
Antimicrobial, Cytotoxic, Anti-Inflammatory, and Antioxidant Activity of Culinary Processed Shiitake Medicinal Mushroom (Lentinus edodes, Agaricomycetes) and Its Major Sulfur Sensory-Active Compound−Lenthionine International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 2
Iveta Stefanova, Roman Kubec, Pavel Hrouzek, Jan Hosek, Zuzana Plavcova, Kristyna Kupcova
Dichloromethane Extract of Fermentation Broth by Co-Culture of Morchella esculenta and Coprinus comatus Induces Apoptosis in U251 Cells via Mitochondrial Intrinsic Pathway International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 10
Huiguo Wang, Xianwei Zou, Liya Li, Xuan Liu, Qian Li, Xiaohong Zhao, Xu Cai, Benke Chen, Hongkun Xue, Linyu Jia, Hongzhu Yu, Xue Zhong, Hua Wang, Jintian Tang
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain