Publicado 4 números por año
ISSN Imprimir: 0731-8898
ISSN En Línea: 2162-6537
Indexed in
Different Advanced Therapeutic Approaches to Treat Vitiligo
SINOPSIS
Vitiligo is a hypopigmentation disorder that is caused by the loss of melanocyte activity for melanin pigment generation. Vitiligo is distinguished by the existence of white macules. Vitiligo affects 0.1%−2% of individuals of different populations, irrespective of skin color, ethnic origin, race, or age. Although the actual mechanism behind this disease is not yet known, it is thought to be caused by a cumulative effect of various mechanisms (e.g., neurohormonal, genetic, cytotoxic, oxidative stress, autoimmune, and biochemical). This article reviews the published literature on various treatment modalities that might be effective in successfully treating patients with vitiligo, including phototherapies or some photochemotherapies, vitamin D analogs, topical and systemic corticosteroids, zinc treatment, anti-tumor necrosis factor agents, calcineurin inhibitors (tacrolimus, pimecrolimus), and surgical methods. This critical review also discusses a few herbal medications that may be worthy of future investigation because they have no significant side effects.
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Fatima Sakeena, Abbas Tazeen, Refat Maggi A., Harris John E., Lim Henry W., Hamzavi Iltefat H., Mohammad Tasneem F., Systemic therapies in vitiligo: a review, International Journal of Dermatology, 2022. Crossref
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Hu Mengjie, Liao Kexin, Lei Wenyi, Zhang Rongxin, Tu Caixia, The addition of topical calcipotriol to phototherapy enhance the efficacy of treatment in patients with vitiligo: A systematic review and meta-analysis, International Immunopharmacology, 98, 2021. Crossref