Suscripción a Biblioteca: Guest
Critical Reviews™ in Immunology

Publicado 6 números por año

ISSN Imprimir: 1040-8401

ISSN En Línea: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Regulation of Antigen-Specific Regulatory T-Cell Induction via Nasal and Oral Mucosa

Volumen 24, Edición 3, 2004, 22 pages
DOI: 10.1615/CritRevImmunol.v24.i3.10
Get accessGet access

SINOPSIS

With the identification of regulatory T cells (Tr), the hunt for ways to specifically intervene in ongoing inflammatory responses has grown exponentially. Tr are attractive for therapy because they have the potential to control deleterious responses while preserving normal immune function. It has long been known that application of soluble antigen via the mucosa induces mucosal Tr that preserve systemic tolerance upon challenge with the same antigen. Mucosal Tr exhibit three major properties that allow selective control of immune responses. They are (1) adaptive—that is, they differentiate from naive T cells in the periphery; (2) antigen-specific—that is, specific for the (exogenous) antigen applied via the mucosa; and (3) versatile—that is, suppress, irrespective of ongoing Th1 or Th2 cytokine polarization. These powerful characteristics provide mucosal Tr with all requirements necessary to selectively interfere in an unbalanced immune system, as occurs in diseases ranging from autoimmunity to transplant rejection and allergy. Until now, however, translation into clinical applications has led to moderate success. This is primarily due to limited knowledge about the fundamental characteristics of these cells because of the lack of a differential marker. The initial stages of mucosal Tr induction, which may hold the key to discovering the identity of mucosal Tr and unraveling their function, are discussed in this review.

CITADO POR
  1. Luna E., Postol E., Caldas C., Benvenuti L. A., Rodrigues J. M., Lima K., Kalil J., Coelho V., Treatment with Encapsulated Hsp60 Peptide (p277) Prolongs Skin Graft Survival in a Murine Model of Minor Antigen Disparity, Scandinavian Journal of Immunology, 66, 1, 2007. Crossref

  2. Orson Frank M., Kinsey Berma M., Densmore Charles L., Nguyen Tina, Wu Yan, Mbawuike Innocent N., Wyde Philip R., Protection against influenza infection by cytokine-enhanced aerosol genetic immunization, The Journal of Gene Medicine, 8, 4, 2006. Crossref

  3. van Wijk F., Wehrens E. J. M., Nierkens S., Boon L., Kasran A., Pieters R., Knippels L. M. J., CD4+CD25+T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization, Clinical & Experimental Allergy, 37, 4, 2007. Crossref

  4. Kraal Georg, Samsom Janneke N., Mebius Reina E., The importance of regional lymph nodes for mucosal tolerance, Immunological Reviews, 213, 1, 2006. Crossref

  5. Bailey M., Haverson K., Inman C., Harris C., Jones P., Corfield G., Miller B., Stokes C., The development of the mucosal immune system pre- and post-weaning: balancing regulatory and effector function, Proceedings of the Nutrition Society, 64, 4, 2005. Crossref

  6. Novak Natalija, Haberstok Jörg, Bieber Thomas, Allam Jean-Pierre, The immune privilege of the oral mucosa, Trends in Molecular Medicine, 14, 5, 2008. Crossref

  7. Kabelitz Dieter, Geissler Edward K., Soria Bernat, Schroeder Insa S., Fändrich Fred, Chatenoud Lucienne, Toward cell-based therapy of type I diabetes, Trends in Immunology, 29, 2, 2008. Crossref

  8. Li Haiyu, Ding Yanping, Yi Guiwen, Zeng Qiutang, Yang Wenkai, Establishment of nasal tolerance to heat shock protein-60 alleviates atherosclerosis by inducing TGF-β-dependent regulatory T cells, Journal of Huazhong University of Science and Technology [Medical Sciences], 32, 1, 2012. Crossref

  9. Kraal Georg, Mebius Reina, , 250, 2006. Crossref

  10. Birmingham Janette M., Patil Sangita, Li Xiu-Min, Busse Paula J., The Effect of Oral Tolerance on the Allergic Airway Response in Younger and Aged Mice, Journal of Asthma, 50, 2, 2013. Crossref

  11. Slütter Bram, Jiskoot Wim, Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination, Journal of Controlled Release, 148, 1, 2010. Crossref

  12. Rossi Oriana, van Berkel Lisette A., Chain Florian, Tanweer Khan M., Taverne Nico, Sokol Harry, Duncan Sylvia H., Flint Harry J., Harmsen Hermie J. M., Langella Philippe, Samsom Janneke N., Wells Jerry M., Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses, Scientific Reports, 6, 1, 2016. Crossref

  13. van Wijk F., Roord S. T., Vastert B., de Kleer I, Wulffraat N., Prakken B. J., Regulatory T cells in autologous stem cell transplantation for autoimmune disease, Autoimmunity, 41, 8, 2008. Crossref

  14. Howe Savannah, Sowa Gavin, Konjufca Vjollca, Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally, Antibodies, 5, 4, 2016. Crossref

  15. Li Xinhui, Johnson Kory R., Bryant Mark, Elkahloun Abdel G., Amar Marcelo, Remaley Alan T., De Silva Ranil, Hallenbeck John M., Quandt Jacqueline A., Zernecke Alma, Intranasal Delivery of E-Selectin Reduces Atherosclerosis in ApoE−/− Mice, PLoS ONE, 6, 6, 2011. Crossref

  16. Chebotareva Natalia, Bobkova Irina, Shilov Evgeniy, Heat shock proteins and kidney disease: perspectives of HSP therapy, Cell Stress and Chaperones, 22, 3, 2017. Crossref

  17. Allam Jean-Pierre, Novak Natalija, Mucosal Homeostasis of the Oral Mucosa, in Oral Mucosa in Health and Disease, 2018. Crossref

  18. Lund Kaare, Kito Hirokazu, Skydtsgaard Mette Blem, Nakazawa Hiroshi, Ohashi-Doi Katsuyo, Lawton Simon, The Importance of Tablet Formulation on Allergen Release Kinetics and Efficiency: Comparison of Freeze-dried and Compressed Grass Pollen Sublingual Allergy Immunotherapy Tablet Formulations, Clinical Therapeutics, 41, 4, 2019. Crossref

  19. Broere Femke, Wieten Lotte, Klein Koerkamp Elles I., van Roon Joel A. G., Guichelaar Teun, Lafeber Floris P. J. G., van Eden Willem, Oral or Nasal Antigen Induces Regulatory T Cells That Suppress Arthritis and Proliferation of Arthritogenic T Cells in Joint Draining Lymph Nodes, The Journal of Immunology, 181, 2, 2008. Crossref

  20. Samsom Janneke N., van der Marel Arnold P. J., van Berkel Lisette A., van Helvoort Joop M. L. M., Simons-Oosterhuis Ytje, Jansen Wendy, Greuter Mascha, Nelissen Rob L. H., Meeuwisse Cees M. L., Nieuwenhuis Edward E. S., Mebius Reina E., Kraal Georg, Secretory Leukoprotease Inhibitor in Mucosal Lymph Node Dendritic Cells Regulates the Threshold for Mucosal Tolerance, The Journal of Immunology, 179, 10, 2007. Crossref

  21. Hasselberg Annemarie, Ekman Lena, Yrlid Linda Fahlén, Schön Karin, Lycke Nils Y., ADP-Ribosylation Controls the Outcome of Tolerance or Enhanced Priming Following Mucosal Immunization, The Journal of Immunology, 184, 6, 2010. Crossref

  22. Chu K-H, Chiang B-L, Characterization and functional studies of forkhead box protein 3− lymphocyte activation gene 3+ CD4+ regulatory T cells induced by mucosal B cells, Clinical and Experimental Immunology, 180, 2, 2015. Crossref

  23. van Eden Willem, van der Zee Ruurd, Prakken Berent, Heat-shock proteins induce T-cell regulation of chronic inflammation, Nature Reviews Immunology, 5, 4, 2005. Crossref

Próximos Artículos

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones Precios y Políticas de Suscripcione Begell House Contáctenos Language English 中文 Русский Português German French Spain